MolNFT v1 · #137158 · protein
Nucleotide-driven triple-state remodeling of the aaa-ATPase channel in the activated human 26S proteasome
5VFR: “Nucleotide-driven triple-state remodeling of the aaa-ATPase channel in the activated human 26S proteasome”. Electron microscopy, 2 ligands (AGS, ZN). MolNFT v1 #137158 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5VFR
- Type
- protein
- Length
- 12,868 residues
- Chains
- 46
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q99460, O43242, O00232, O00231, Q15008, P51665, Q9UNM6, P55036, O00487, P48556, P60900, P25787, P25789, O14818, P28066, P25786, P25788, P28072, Q99436, P49720, P49721, P28074, P20618, P28070, P35998, P62191, P62195, P43686, P62333, P17980, Q13200
- Ligands
- AGS, ZN
Structure
electron microscopy · 35 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| U | — | protein | 806 | — | Q99460 |
| V | — | protein | 472 | — | O43242 |
| W | — | protein | 456 | — | O00232 |
| X | — | protein | 241 | — | O00231 |
| Y | — | protein | 378 | — | Q15008 |
| Z | — | protein | 286 | — | P51665 |
| a | — | protein | 373 | — | Q9UNM6 |
| b | — | protein | 191 | — | P55036 |
| c | — | protein | 278 | — | O00487 |
| d | — | protein | 257 | — | P48556 |
| e | — | protein | 40 | — | — |
| G | — | protein | 239 | — | P60900 |
| H | — | protein | 230 | — | P25787 |
| I | — | protein | 248 | — | P25789 |
| J, j | — | protein | 239 | — | O14818 |
| K, k | — | protein | 228 | — | P28066 |
| L, l | — | protein | 238 | — | P25786 |
| M, m | — | protein | 240 | — | P25788 |
| N, n | — | protein | 191 | — | P28072 |
| O, o | — | protein | 220 | — | Q99436 |
| P, p | — | protein | 204 | — | P49720 |
| Q, q | — | protein | 199 | — | P49721 |
| R, r | — | protein | 201 | — | P28074 |
| S, s | — | protein | 213 | — | P20618 |
| T, t | — | protein | 215 | — | P28070 |
| g | — | protein | 240 | — | P60900 |
| h | — | protein | 232 | — | P25787 |
| i | — | protein | 250 | — | P25789 |
| A | — | protein | 342 | — | P35998 |
| B | — | protein | 350 | — | P62191 |
| C | — | protein | 363 | — | P62195 |
| D | — | protein | 380 | — | P43686 |
| E | — | protein | 375 | — | P62333 |
| F | — | protein | 376 | — | P17980 |
| f | — | protein | 689 | — | Q13200 |
Ligands and binding sites
- AGS · Phosphothiophosphoric acid-adenylate ester · ligand · 4 copies · chains A, B, C, D, E, F
- ZN · Zinc ion · metal · chains c
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5VFR · Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated… · the same entry in another collection · chain e against e, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99460
- Every structure of UniProt O43242
- Every structure of UniProt O00232
- Every structure of UniProt O00231
- Every structure of UniProt Q15008
- Every structure of UniProt P51665
- Every structure of UniProt Q9UNM6
- Every structure of UniProt P55036
- Every structure of UniProt O00487
- Every structure of UniProt P48556
- Every structure of UniProt P60900
- Every structure of UniProt P25787
- Every structure of UniProt P25789
- Every structure of UniProt O14818
- Every structure of UniProt P28066
- Every structure of UniProt P25786
- Every structure of UniProt P25788
- Every structure of UniProt P28072
- Every structure of UniProt Q99436
- Every structure of UniProt P49720
- Every structure of UniProt P49721
- Every structure of UniProt P28074
- Every structure of UniProt P20618
- Every structure of UniProt P28070
- Every structure of UniProt P35998
- Every structure of UniProt P62191
- Every structure of UniProt P62195
- Every structure of UniProt P43686
- Every structure of UniProt P62333
- Every structure of UniProt P17980
- Every structure of UniProt Q13200
- Elsewhere: RCSB PDB 5VFR · PDBe 5VFR · UniProt Q99460 · UniProt O43242 · UniProt O00232 · UniProt O00231 · UniProt Q15008 · UniProt P51665 · UniProt Q9UNM6 · UniProt P55036 · UniProt O00487 · UniProt P48556 · UniProt P60900 · UniProt P25787 · UniProt P25789 · UniProt O14818 · UniProt P28066 · UniProt P25786 · UniProt P25788 · UniProt P28072 · UniProt Q99436 · UniProt P49720 · UniProt P49721 · UniProt P28074 · UniProt P20618 · UniProt P28070 · UniProt P35998 · UniProt P62191 · UniProt P62195 · UniProt P43686 · UniProt P62333 · UniProt P17980 · UniProt Q13200
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