UniProt P51665
26S proteasome non-ATPase regulatory subunit 7 (P51665)
26S proteasome non-ATPase regulatory subunit 7 (UniProt P51665): 31 experimental structures and 1 predicted model on GenesisL1, 30 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P51665
- Protein
- 26S proteasome non-ATPase regulatory subunit 7
- Experimental structures
- 31
- Predicted models
- 1
- Pockets
- 30 · 8 records with a druggable one
Structures
32 records of P51665 in the MolNFT archive: 31 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2O95 | Crystal Structure of the Metal-Free Dimeric Human Mov34 MPN domain (residues 1-186) | x-ray diffraction | A, B | — | — |
| 2O95 | Crystal structure of the metal-free dimeric human MOV34 mpn domain (residues 1-186) | x-ray diffraction | A, B | — | — |
| 2O96 | Crystal Structure of the Metal-Free Dimeric Human Mov34 MPN domain (residues 1-177) | x-ray diffraction | A, B | — | — |
| 2O96 | Crystal structure of the metal-free dimeric human MOV34 mpn domain (residues 1-177) | x-ray diffraction | A, B | — | — |
| 5GJQ | Structure of the human 26S proteasome bound to USP14-ubal | electron microscopy | U | — | — |
| 5GJR | An atomic structure of the human 26S proteasome | electron microscopy | U, 8 | — | — |
| 5L4K | The human 26S proteasome lid | electron microscopy | U | — | — |
| 5LN3 | The human 26S proteasome at 6.8 ang. | electron microscopy | U | — | — |
| 5M32 | Human 26S proteasome in complex with oprozomib | electron microscopy | n | — | — |
| 5T0G | Structural basis for dynamic regulation of the human 26S proteasome | electron microscopy | Z | — | 4 (best 0.84) |
| 5T0G | Structural basis for dynamic regulation of the human 26S proteasome | electron microscopy | Z | — | — |
| 5T0H | Structural basis for dynamic regulation of the human 26S proteasome | electron microscopy | Z | — | — |
| 5T0I | Structural basis for dynamic regulation of the human 26S proteasome | electron microscopy | Z | — | — |
| 5T0J | Structural basis for dynamic regulation of the human 26S proteasome | electron microscopy | Z | — | — |
| 5VFR | Nucleotide-driven triple-state remodeling of the aaa-ATPase channel in the activated human 26S… | electron microscopy | Z | — | — |
| 5VFT | Nucleotide-driven triple-state remodeling of the aaa-ATPase channel in the activated human 26S… | electron microscopy | Z | — | — |
| 5VFU | Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S… | electron microscopy | Z | — | — |
| 5VGZ | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | electron microscopy | Z | — | 5 (best 0.86) |
| 5VGZ | Conformational landscape of the P28-bound human proteasome regulatory particle | electron microscopy | Z | — | — |
| 5VHF | Conformational landscape of the P28-bound human proteasome regulatory particle | electron microscopy | Z | — | — |
| 5VHH | Conformational landscape of the P28-bound human proteasome regulatory particle | electron microscopy | Z | — | — |
| 5VHI | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | electron microscopy | Z | — | 4 (best 0.89) |
| 5VHI | Conformational landscape of the P28-bound human proteasome regulatory particle | electron microscopy | Z | — | — |
| 5VHS | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | electron microscopy | Z | — | 4 (best 0.88) |
| 5VHS | Conformational landscape of the P28-bound human proteasome regulatory particle | electron microscopy | Z | — | — |
| 6MSD | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome | electron microscopy | Z | — | 2 (best 0.80) |
| 6WJN | Sd-like state of human 26S proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin… | electron microscopy | Z | — | — |
| 7W39 | Structure of USP14-bound human 26S proteasome in state EA2.1_UBL | electron microscopy | Z | — | 3 (best 0.80) |
| 7W3I | Structure of USP14-bound human 26S proteasome in substrate-inhibited state SB_USP14 | electron microscopy | Z | — | — |
| 8JRI | Cryo-EM structure of human 26S proteasomal RP subcomplex (Ea state) without any bound substrate. | electron microscopy | Z | — | 2 (best 0.78) |
| 9E8Q | Nub1/Fat10-processing human 26S proteasome with Rpt2 at top of spiral staircase | electron microscopy | Z | — | 3 (best 0.79) |
| P51665 | AlphaFold monomer V2.0 prediction for 26S proteasome non-ATPase regulatory subunit 7 (P51665) | predicted | A | — | 3 (best 0.33) |
Experiment against prediction
- 2O96 chain A against the predicted model P51665: TM-score 0.94, RMSD 1.38 Å
- 2O96 chain A against the predicted model P51665: TM-score 0.94, RMSD 1.38 Å
- 2O96 chain B against the predicted model P51665: TM-score 0.93, RMSD 1.39 Å
- 2O96 chain B against the predicted model P51665: TM-score 0.93, RMSD 1.39 Å
- 2O95 chain B against the predicted model P51665: TM-score 0.90, RMSD 1.92 Å
- 2O95 chain B against the predicted model P51665: TM-score 0.90, RMSD 1.92 Å
- 2O95 chain A against the predicted model P51665: TM-score 0.88, RMSD 1.92 Å
- 2O95 chain A against the predicted model P51665: TM-score 0.88, RMSD 1.92 Å
- 9E8Q chain Z against the predicted model P51665: TM-score 0.81, RMSD 3.10 Å
- 7W39 chain Z against the predicted model P51665: TM-score 0.81, RMSD 3.25 Å
Elsewhere
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