Families & evolution
Couplings (DCA)
Run mean-field direct coupling analysis on an alignment or a chain's homologs and compare the strongest co-evolving residue pairs with the contacts of the structure.
Find co-evolving residue pairs with mean-field direct coupling analysis and compare them with the structure's contacts.
- APC-corrected couplings and direct information
- Precision of the top L/5, L/2 and L pairs as contacts
- From an alignment or a chain's homologs
Equal to the reference dca.m to 10⁻⁶.
Families, evolution and variants · free, no account; also through the API and the MCP server.
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