UniProt Q9UNM6
26S proteasome non-ATPase regulatory subunit 13 (Q9UNM6)
26S proteasome non-ATPase regulatory subunit 13 (UniProt Q9UNM6): 26 experimental structures and 1 predicted model on GenesisL1, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UNM6
- Protein
- 26S proteasome non-ATPase regulatory subunit 13
- Experimental structures
- 26
- Predicted models
- 1
- Pockets
- 21 · 7 records with a druggable one
Structures
27 records of Q9UNM6 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GJQ | Structure of the human 26S proteasome bound to USP14-ubal | electron microscopy | O | — | — |
| 5GJR | An atomic structure of the human 26S proteasome | electron microscopy | O, 2 | — | — |
| 5L4K | The human 26S proteasome lid | electron microscopy | O | — | — |
| 5LN3 | The human 26S proteasome at 6.8 ang. | electron microscopy | O | — | — |
| 5M32 | Human 26S proteasome in complex with oprozomib | electron microscopy | o | — | — |
| 5T0G | Structural basis for dynamic regulation of the human 26S proteasome | electron microscopy | a | — | 2 (best 0.82) |
| 5T0G | Structural basis for dynamic regulation of the human 26S proteasome | electron microscopy | a | — | — |
| 5T0H | Structural basis for dynamic regulation of the human 26S proteasome | electron microscopy | a | — | — |
| 5T0I | Structural basis for dynamic regulation of the human 26S proteasome | electron microscopy | a | — | — |
| 5T0J | Structural basis for dynamic regulation of the human 26S proteasome | electron microscopy | a | — | — |
| 5VFR | Nucleotide-driven triple-state remodeling of the aaa-ATPase channel in the activated human 26S… | electron microscopy | a | — | — |
| 5VFU | Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S… | electron microscopy | a | — | — |
| 5VGZ | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | electron microscopy | a | — | 4 (best 0.86) |
| 5VGZ | Conformational landscape of the P28-bound human proteasome regulatory particle | electron microscopy | a | — | — |
| 5VHF | Conformational landscape of the P28-bound human proteasome regulatory particle | electron microscopy | a | — | — |
| 5VHH | Conformational landscape of the P28-bound human proteasome regulatory particle | electron microscopy | a | — | — |
| 5VHI | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | electron microscopy | a | — | 4 (best 0.89) |
| 5VHI | Conformational landscape of the P28-bound human proteasome regulatory particle | electron microscopy | a | — | — |
| 5VHS | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | electron microscopy | a | — | 5 (best 0.88) |
| 5VHS | Conformational landscape of the P28-bound human proteasome regulatory particle | electron microscopy | a | — | — |
| 6MSD | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome | electron microscopy | a | — | 1 (best 0.80) |
| 6WJN | Sd-like state of human 26S proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin… | electron microscopy | a | — | — |
| 7W39 | Structure of USP14-bound human 26S proteasome in state EA2.1_UBL | electron microscopy | a | — | — |
| 7W3I | Structure of USP14-bound human 26S proteasome in substrate-inhibited state SB_USP14 | electron microscopy | a | — | — |
| 8JRI | Cryo-EM structure of human 26S proteasomal RP subcomplex (Ea state) without any bound substrate. | electron microscopy | a | — | — |
| 9E8Q | Nub1/Fat10-processing human 26S proteasome with Rpt2 at top of spiral staircase | electron microscopy | a | — | 1 (best 0.79) |
| Q9UNM6 | AlphaFold monomer V2.0 prediction for 26S proteasome non-ATPase regulatory subunit 13 (Q9UNM6) | predicted | A | — | 4 (best 0.60) |
Experiment against prediction
- 5L4K chain O against the predicted model Q9UNM6: TM-score 0.91, RMSD 2.35 Å
- 5GJR chain O against the predicted model Q9UNM6: TM-score 0.91, RMSD 2.47 Å
- 5GJQ chain O against the predicted model Q9UNM6: TM-score 0.91, RMSD 2.49 Å
- 7W39 chain a against the predicted model Q9UNM6: TM-score 0.89, RMSD 2.53 Å
- 8JRI chain a against the predicted model Q9UNM6: TM-score 0.89, RMSD 2.57 Å
- 5T0G chain a against the predicted model Q9UNM6: TM-score 0.89, RMSD 2.58 Å
- 5T0G chain a against the predicted model Q9UNM6: TM-score 0.89, RMSD 2.58 Å
- 6MSD chain a against the predicted model Q9UNM6: TM-score 0.89, RMSD 2.55 Å
- 5VFU chain a against the predicted model Q9UNM6: TM-score 0.89, RMSD 2.56 Å
- 5T0I chain a against the predicted model Q9UNM6: TM-score 0.89, RMSD 2.56 Å
Elsewhere
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