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Bovine complex I in lipid nanodisc, active-Q10

Analyse Bovine complex I in lipid nanodisc, active-Q10 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7QSK
Type
protein
Length
8,291 residues
Chains
45
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q7JAS9, P42026, P23709, P17694, P04394, P25708, P15690, P03887, P42028, P03924, P03902, P03920, P03910, P03892, P34942, P34943, Q02375, P23934, Q02370, P52505, P23935, Q02366, P42029, Q8HXG6, Q95KV7, Q02377, Q02371, Q02376, Q02827, Q02379, Q02378, Q8HXG5, Q02380, Q02367, Q02374, Q02365, Q02372, P48305, Q02369, Q02368, Q02373, O97725, Q05752, P25712
Ligands
3PE, PC1, CDL, SF4, FES, EHZ, U10, FMN, GTP, NDP, CHD, MYR, K, MG, ZN

Structure

electron microscopy · 45 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein115—Q7JAS9
B—protein155—P42026
C—protein209—P23709
D—protein430—P17694
E—protein214—P04394
F—protein432—P25708
G—protein699—P15690
H—protein318—P03887
I—protein176—P42028
J—protein175—P03924
K—protein98—P03902
L—protein606—P03920
M—protein459—P03910
N—protein347—P03892
O—protein320—P34942
P—protein342—P34943
Q—protein129—Q02375
R—protein96—P23934
S—protein87—Q02370
T—protein85—P52505
U—protein86—P52505
V—protein115—P23935
W—protein115—Q02366
X—protein171—P42029
Y—protein140—Q8HXG6
Z—protein141—Q95KV7
a—protein70—Q02377
b—protein83—Q02371
c—protein49—Q02376
d—protein120—Q02827
e—protein99—Q02379
f—protein57—Q02378
g—protein100—Q8HXG5
h—protein138—Q02380
i—protein127—Q02367
j—protein71—Q02374
k—protein81—Q02365
l—protein156—Q02372
m—protein128—P48305
n—protein172—Q02369
o—protein122—Q02368
p—protein173—Q02373
q—protein145—O97725
r—protein95—Q05752
s—protein45—P25712

Ligands and binding sites

  • 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · ligand · 19 copies · chains A, H, b, J, K, L, M, l, i, j, o, D, N, m, Y, O, d, P, e
  • PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · ligand · 14 copies · chains A, H, P, J, e, B, D, I, Z, b, r, M, Y, L, m, a, N, d, g, h, p, q
  • CDL · Cardiolipin · ligand · 7 copies · chains H, J, P, L, M, h, N, O, X, d, f, c, g, i, p, a, q, r
  • SF4 · Iron/sulfur cluster · ligand · 6 copies · chains B, D, F, G, I
  • FES · Fe2/s2 (inorganic) cluster · ligand · 2 copies · chains E, G
  • EHZ · ~{S}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{S})-3-oxidanyltetradecanethioate · ligand · 2 copies · chains T, W, L, U, n
  • U10 · Ubiquinone-10 · ligand · chains B, D, H
  • FMN · Flavin mononucleotide · ligand · chains F
  • GTP · Guanosine-5'-triphosphate · ligand · chains O
  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · ligand · chains B, P
  • CHD · Cholic acid · ligand · chains L, i
  • MYR · Myristic acid · ligand · chains L, l, o
  • K · Potassium ion · metal · chains G
  • MG · Magnesium ion · metal · chains O
  • ZN · Zinc ion · metal · chains R

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7QSK · Bovine complex I in lipid nanodisc, Active-Q10 · the same entry in another collection · chain J against J, TM-score 1.00

Analyse

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