UniProt Q7JAS9
NADH-ubiquinone oxidoreductase chain 3 (Q7JAS9)
NADH-ubiquinone oxidoreductase chain 3 (UniProt Q7JAS9), EC 7.1.1.2: 38 experimental structures on GenesisL1, 6 ligands bound, 88 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q7JAS9
- Protein
- NADH-ubiquinone oxidoreductase chain 3
- EC
- 7.1.1.2
- Experimental structures
- 38
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 88 · 29 records with a druggable one
Structures
38 records of Q7JAS9 in the MolNFT archive: 38 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7QSD | Bovine complex I in the active state at 3.1 A | electron microscopy | A | PC1, 3PE | 2 (best 0.85) |
| 7QSD | Bovine complex I in the active state at 3.1 a | electron microscopy | A | PC1, 3PE | — |
| 7QSK | Bovine complex I in lipid nanodisc, Active-Q10 | electron microscopy | A | 3PE, PC1, U10 | 3 (best 0.87) |
| 7QSK | Bovine complex I in lipid nanodisc, active-Q10 | electron microscopy | A | 3PE, PC1 | — |
| 7QSL | Bovine complex I in lipid nanodisc, active-apo | electron microscopy | A | 3PE, PC1 | — |
| 7QSM | Bovine complex I in lipid nanodisc, Deactive-ligand (composite) | electron microscopy | A | 3PE, PC1 | 3 (best 0.86) |
| 7QSM | Bovine complex I in lipid nanodisc, deactive-ligand (composite) | electron microscopy | A | 3PE, PC1 | — |
| 7QSN | Bovine complex I in lipid nanodisc, Deactive-apo | electron microscopy | A | PC1, 3PE | 3 (best 0.88) |
| 7QSN | Bovine complex I in lipid nanodisc, deactive-apo | electron microscopy | A | PC1, 3PE | — |
| 7QSO | Bovine complex I in lipid nanodisc, State 3 (Slack) | electron microscopy | A | 3PE, PC1 | — |
| 7QSO | Bovine complex I in lipid nanodisc, state 3 (slack) | electron microscopy | A | 3PE, PC1 | — |
| 7R41 | Bovine complex I in the presence of IM1761092, active class i (Composite map) | electron microscopy | A | PC1, 3PE, CDL | 4 (best 0.87) |
| 7R42 | Bovine complex I in the presence of IM1761092, active class ii (Composite map) | electron microscopy | A | PC1, 3PE | 3 (best 0.92) |
| 7R43 | Bovine complex I in the presence of IM1761092, active class iii (Composite map) | electron microscopy | A | PC1, 3PE | — |
| 7R44 | Bovine complex I in the presence of IM1761092, active class iv (Composite map) | electron microscopy | A | PC1, 3PE, CDL | 4 (best 0.90) |
| 7R45 | Bovine complex I in the presence of IM1761092, deactive class i (Composite map) | electron microscopy | A | 3PE, NDP | 3 (best 0.87) |
| 7R46 | Bovine complex I in the presence of IM1761092, deactive class ii (Composite map) | electron microscopy | A | 3PE | 5 (best 0.89) |
| 7R47 | Bovine complex I in the presence of IM1761092, deactive class iii (Composite map) | electron microscopy | A | 3PE, NDP | — |
| 7R48 | Bovine complex I in the presence of IM1761092, deactive class iv (Composite map) | electron microscopy | A | 3PE, NDP | 4 (best 0.89) |
| 7R4C | Bovine complex I in the presence of IM1761092, deactive class v (Composite map) | electron microscopy | A | 3PE, NDP | 3 (best 0.86) |
| 7R4D | Bovine complex I in the presence of IM1761092, deactive class vi (Composite map) | electron microscopy | A | 3PE, NDP | 5 (best 0.89) |
| 7R4F | Bovine complex I in the presence of IM1761092, slack class i (Composite map) | electron microscopy | A | PC1, 3PE | 4 (best 0.88) |
| 7R4G | Bovine complex I in the presence of IM1761092, slack class ii (Composite map) | electron microscopy | A | 3PE | 2 (best 0.88) |
| 8Q0A | Inward-facing, closed proteoliposome complex I at 3.1 A. Initially purified in DDM. | electron microscopy | A | 3PE, PC1, PLC | 4 (best 0.88) |
| 8Q0F | Inward-facing, open2 proteoliposome complex I at 3.1 A. Initially purified in DDM. | electron microscopy | A | 3PE, PC1, PLC | 2 (best 0.88) |
| 8Q0J | Inward-facing, slack proteoliposome complex I at 3.8 A. Initially purified in DDM. | electron microscopy | A | 3PE, PC1 | 3 (best 0.90) |
| 8Q0M | Outward-facing, closed proteoliposome complex I at 3.1 A. Initially purified in DDM. | electron microscopy | A | 3PE, PC1, PLC, CDL | 2 (best 0.86) |
| 8Q0O | Outward-facing, open2 proteoliposome complex I at 3.1 A. Initially purified in DDM. | electron microscopy | A | 3PE, PC1, PLC | 2 (best 0.88) |
| 8Q0Q | Outward-facing, slack proteoliposome complex I at 3.6 A. Initially purified in DDM | electron microscopy | A | 3PE, PC1 | 2 (best 0.90) |
| 8Q1P | Inward-facing, open2 proteoliposome complex I at 2.9 A, after deactivation treatment. Initially… | electron microscopy | A | 3PE, PC1, PLC | 2 (best 0.90) |
| 8Q1U | Inward-facing, open1 proteoliposome complex I at 3.3 A, after deactivation treatment. Initially… | electron microscopy | A | 3PE, PC1, PLC | 3 (best 0.86) |
| 8Q1Y | Outward-facing, open2 proteoliposome complex I at 2.6 A, after deactivation treatment. Initially… | electron microscopy | A | 3PE, PC1, PLC | 3 (best 0.86) |
| 8Q25 | Outward-facing, open1 proteoliposome complex I at 2.8 A, after deactivation treatment. Initially… | electron microscopy | A | 3PE, PC1, CDL, PLC | 3 (best 0.87) |
| 8Q46 | Inward-facing, open2 proteoliposome complex I at 2.6 A. Initially purified in LMNG. | electron microscopy | A | 3PE, PC1, PLC | 2 (best 0.89) |
| 8Q47 | Inward-facing, open1 proteoliposome complex I at 2.9 A. Initially purified in LMNG. | electron microscopy | A | PC1, 3PE, PLC | 4 (best 0.87) |
| 8Q48 | Outward-facing, closed proteoliposome complex I at 2.5 A. Initially purified in LMNG. | electron microscopy | A | PC1, 3PE, PLC, CDL | 2 (best 0.90) |
| 8Q49 | Outward-facing, open2 proteoliposome complex I at 2.6 A. Initially purified in LMNG. | electron microscopy | A | PC1, 3PE, PLC | 2 (best 0.87) |
| 8Q4A | Outward-facing, open1 proteoliposome complex I at 2.6 A. Initially purified in LMNG. | electron microscopy | A | 3PE, PC1, PLC, CDL | 4 (best 0.89) |
Ligands
- 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · in 38 records
- PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · in 31 records
- PLC · Diundecyl phosphatidyl choline · in 13 records
- CDL · Cardiolipin · in 6 records
- NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · in 5 records
- U10 · Ubiquinone-10 · in 1 record
Elsewhere
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