GL1X · GenesisL1 explorer

MolNFT v2 · #192194 · protein

Bovine complex I in lipid nanodisc, State 3 (Slack)

7QSO: “Bovine complex I in lipid nanodisc, State 3 (Slack)”. Electron microscopy at 3.02, 15 ligands (3PE, PC1, SF4). MolNFT v2 #192194 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7QSO
Type
protein
Length
8,018 residues
Chains
45
Method
electron microscopy
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
3.02
Source
Bos taurus
UniProt
Q7JAS9, P42026, P23709, P17694, P04394, P25708, P15690, P03887, P42028, P03924, P03902, P03920, P03910, P03892, P34942, P34943, Q02375, P23934, Q02370, P52505, P23935, Q02366, P42029, Q8HXG6, Q95KV7, Q02377, Q02371, Q02376, Q02827, Q02379, Q02378, Q8HXG5, Q02380, Q02367, Q02374, Q02365, Q02372, P48305, Q02369, Q02368, Q02373, O97725, Q05752, P25712
Ligands
3PE, PC1, SF4, CDL, FES, CHD, EHZ, FMN, U10, GTP, NDP, MYR, K, MG, ZN

Structure

electron microscopy · resolution 3.02 · 45 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein107—Q7JAS9
B—protein158—P42026
C—protein210—P23709
D—protein388—P17694
E—protein214—P04394
F—protein432—P25708
G—protein700—P15690
H—protein318—P03887
I—protein176—P42028
J—protein161—P03924
K—protein86—P03902
L—protein547—P03920
M—protein459—P03910
N—protein347—P03892
O—protein320—P34942
P—protein320—P34943
Q—protein125—Q02375
R—protein96—P23934
S—protein87—Q02370
T—protein84—P52505
U—protein88—P52505
V—protein113—P23935
W—protein115—Q02366
X—protein171—P42029
Y—protein33—Q8HXG6
Z—protein142—Q95KV7
a—protein70—Q02377
b—protein83—Q02371
c—protein48—Q02376
d—protein120—Q02827
e—protein99—Q02379
f—protein57—Q02378
g—protein90—Q8HXG5
h—protein143—Q02380
i—protein127—Q02367
j—protein70—Q02374
k—protein81—Q02365
l—protein156—Q02372
m—protein127—P48305
n—protein171—Q02369
o—protein120—Q02368
p—protein173—Q02373
q—protein145—O97725
r—protein96—Q05752
s—protein45—P25712

Ligands and binding sites

  • 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · ligand · 14 copies · chains A, b, H, J, N, D, I, Z, r, L, M, l, i, d, c, e, Y, h, p
  • PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · ligand · 6 copies · chains A, B, H, P, q, J, Z, a, L, M, g, N, d, e
  • SF4 · Iron/sulfur cluster · ligand · 6 copies · chains B, D, F, G, I
  • CDL · Cardiolipin · ligand · 6 copies · chains L, M, g, h, N, O, X, d, f, c, i, p, H, a, q, r
  • FES · Fe2/s2 (inorganic) cluster · ligand · 2 copies · chains E, G
  • CHD · Cholic acid · ligand · 2 copies · chains B, H, L, i
  • EHZ · ~{S}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{S})-3-oxidanyltetradecanethioate · ligand · 2 copies · chains T, W, L, U, n
  • FMN · Flavin mononucleotide · ligand · chains F
  • U10 · Ubiquinone-10 · ligand · chains M, N
  • GTP · Guanosine-5'-triphosphate · ligand · chains O
  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · ligand · chains B, P
  • MYR · Myristic acid · ligand · chains L, o
  • K · Potassium ion · metal · chains G
  • MG · Magnesium ion · metal · chains O
  • ZN · Zinc ion · metal · chains R

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7QSO · Bovine complex I in lipid nanodisc, state 3 (slack) · the same entry in another collection · chain K against K, TM-score 1.00

Analyse

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