GTP · Guanosine-5'-triphosphate

Binding sites

GTP in 1,059 structures; the first of them:

• 4X1K · Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications · GTP A600 · binds GLY10, GLN11, ALA12, GLN15, ILE16, ASP69, LEU70, GLU71 and 18 more
• 4XUL · Crystal structure of M. chilensis Mg662 protein complexed with GTP · GTP A404 · binds GLY50, SER51, THR60, ASP61, ASP63, GLN229, LEU232, ALA233 and 7 more
• 4Y1J · Lactococcus lactis yybP-ykoY Mn riboswitch A41U binding site mutant in presence of Mn2+ · GTP A201 · binds A3, U100, C101
• 4Y1M · An Escherichia coli yybP-ykoY Mn riboswitch in the Mn2+-free state · GTP B212 · binds G2, C107, C108
• 4ZHQ · Crystal structure of Tubulin-Stathmin-TTL-MMAE Complex · GTP A501 · binds GLY10, GLN11, ALA12, GLN15, ILE16, ASP69, ASP98, ALA99 and 21 more
• 4ZI7 · Crystal structure of tubulin-stathmin-ttl-HTI286 complex · GTP A501 · binds VAL9, GLY10, GLN11, ALA12, GLN15, ILE16, ASP69, ASP98 and 23 more
• 4ZOL · Crystal Structure of Tubulin-Stathmin-TTL-Tubulysin M Complex · GTP A501 · binds GLY10, GLN11, ALA12, GLN15, ILE16, ASP69, ASP98, ALA99 and 20 more
• 5AXL · Crystal structure of Thg1 like protein (TLP) with GTP · GTP A301 · binds ASP21, GLY22, ARG23, ASN24, PHE25, LYS26, LEU29, PHE34 and 8 more
• 5BMV · CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-Vinblastine COMPLEX · GTP A501 · binds GLY10, GLN11, ALA12, GLN15, ILE16, ASP69, ASP98, ALA99 and 20 more
• 5C1T · Crystal structure of the GTP-bound wild type EhRabX3 from Entamoeba histolytica · GTP A401 · binds SER28, SER29, GLY30, VAL31, GLY32, LYS33, THR34, THR35 and 7 more
• 5C8Y · Crystal structure of T2R-TTL-Plinabulin complex · GTP A501 · binds GLY10, GLN11, ALA12, GLN15, ILE16, ASP69, ASP98, ALA99 and 18 more
• 5CA0 · Crystal structure of T2R-TTL-Lexibulin complex · GTP A501 · binds GLY10, GLN11, ALA12, GLN15, ILE16, ASP69, ASP98, ALA99 and 18 more
• 5CB4 · Crystal structure of T2R-TTL-Tivantinib complex · GTP A501 · binds GLY10, GLN11, ALA12, GLN15, ILE16, ASP69, ASP98, ALA99 and 20 more
• 5D0E · Crystal Structure of an adenylyl cyclase Ma1120-Cat in complex with GTP and calcium from… · GTP A302 · binds PHE111, LYS153, GLN155, GLY156, VAL215, ALA216, ALA219, ARG220 and 9 more
• 5D0G · Crystal structure of triple mutant (KDA to EGY) of adenylyl cyclase Ma1120 from… · GTP A301 · binds ASP113, ILE114, GLU115, GLU116, SER117, THR118, SER154, GLN155 and 15 more
• 5DIS · Crystal structure of a CRM1-RanGTP-SPN1 export complex bound to a 113 amino acid… · GTP B201 · binds ASP18, GLY19, GLY20, THR21, GLY22, LYS23, THR24, THR25 and 20 more
• 5DLQ · Crystal structure of RanGTP-Exportin 4-eIF5A complex · GTP C217 · binds PRO974, ASP18, GLY19, GLY20, THR21, GLY22, LYS23, THR24 and 20 more
• 5EFC · Structure of Influenza B Lee PB2 cap-binding domain bound to GTP · GTP A501 · binds GLN325, PHE327, ARG334, LYS341, TRP359, GLU363, PHE365, LYS378 and 2 more
• 5EIB · Crystal structure of CPAP PN2-3 C-terminal loop-helix in complex with DARPin-tubulin · GTP C501 · binds GLY10, GLN11, ALA12, GLN15, ILE16, ASP69, ASP98, ALA99 and 20 more
• 5EXY · Crystal structure of in cellulo recombinant CPV1 Polyhedra · GTP A307 · binds HIS170, TYR172, ASN173
• 5EXZ · Crystal structure of purified recombinant CPV1 Polyhedra · GTP A307 · binds HIS170, TYR172, ASN173
• 5EY0 · Crystal structure of CodY from Staphylococcus aureus with GTP and Ile · GTP B302 · binds ALA21, VAL22, ASP23, PHE24, SER43, ARG44, ARG45, LYS47 and 7 more
• 5EYP · Tubulin-darpin complex · GTP A501 · binds GLY10, GLN11, ALA12, GLN15, ILE16, ASP69, ASP98, ALA99 and 20 more

Residues it binds most

GLY 3196, ASN 2939, ALA 2866, THR 3039, GLN 2884, ASP 3082, LYS 2861, ILE 2370, SER 2620, GLU 2629 (residue and the binding sites it lines).

Found with

• MG · Magnesium ion
• GDP · Guanosine-5'-diphosphate
• CA · Calcium ion
• MES · 2-(N-morpholino)-ethanesulfonic acid
• ACP · Phosphomethylphosphonic acid adenylate ester
• ZN · Zinc ion
• GOL · Glycerol
• TA1 · Taxol
• CL · Chloride ion
• NA · Sodium ion
• ANP · Phosphoaminophosphonic acid-adenylate ester
• IHP · Inositol hexakisphosphate