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Tfiid-based intermediate pic on puma promoter

Analyse Tfiid-based intermediate pic on puma promoter in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7EGA
Type
protein + DNA
Length
10,443 residues
Chains
41
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P21675, Q6P1X5, O00268, Q15542, P49848, Q15545, Q7Z7C8, Q16594, Q12962, Q16514, P52657, P20226, P52655, Q00403, P35269, P13984, P29083, P29084, Q5VWG9, Q15544, Q15543, A0A480TA59, A0A4X1TVZ5, A0A481DF93, A0A481BYI6, A0A4X1VTX4, A0A4X1VEK9, A0A4X1ULF2, P60899, A0A4X1UK25, A0A4X1TRS6, A0A4X1VKG7
Ligands
ZN, MG

Structure

electron microscopy · 41 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein602—P21675
B—protein963—Q6P1X5
D—protein164—O00268
E—protein546—Q15542
F—protein404—P49848
G—protein145—Q15545
H—protein209—Q7Z7C8
I—protein120—Q16594
J—protein89—Q12962
L—protein76—Q16514
O—protein97—P52657
P—protein177—P20226
Q—protein122—P52655
R—protein251—Q00403
S—protein108—P35269
T—protein222—P13984
U—protein179—P29083
V—protein172—P29084
c—protein127—Q5VWG9
d—protein158—O00268
e—protein539—Q15542
f—protein403—P49848
i—protein121—Q16594
j—protein95—Q12962
k—protein98—Q15544
l—protein107—Q16514
m—protein87—Q15543
o—protein1427—A0A480TA59
p—protein1134—A0A4X1TVZ5
q—protein257—A0A481DF93
r—protein128—A0A481BYI6
s—protein209—A0A4X1VTX4
t—protein79—A0A4X1VEK9
v—protein148—A0A4X1ULF2
w—protein114—P60899
x—protein64——
y—protein117—A0A4X1UK25
z—protein44—A0A4X1TRS6
X—dna85——
Y—dna85——
u—protein171—A0A4X1VKG7

Ligands and binding sites

  • ZN · Zinc ion · metal · 10 copies · chains R, U, o, p, q, w, x, z
  • MG · Magnesium ion · metal · chains o

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7EGA · TFIID-based intermediate PIC on PUMA promoter · the same entry in another collection · chain O against O, TM-score 1.00

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