UniProt A0A4X1VKG7
DNA-directed RNA polymerase II subunit RPB7 (A0A4X1VKG7)
DNA-directed RNA polymerase II subunit RPB7 (UniProt A0A4X1VKG7): 43 experimental structures on GenesisL1, 54 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A4X1VKG7
- Protein
- DNA-directed RNA polymerase II subunit RPB7
- Experimental structures
- 43
- Predicted models
- 0
- Pockets
- 54 · 32 records with a druggable one
Structures
43 records of A0A4X1VKG7 in the MolNFT archive: 43 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7EDX | p53-bound TFIID-based core PIC on HDM2 promoter | electron microscopy | u | — | 2 (best 0.82) |
| 7EDX | P53-bound tfiid-based core pic on HDM2 promoter | electron microscopy | u | — | — |
| 7EG7 | Tfiid-based core pic on scp promoter | electron microscopy | u | — | — |
| 7EG8 | Tfiid-based core pic on puma promoter | electron microscopy | u | — | — |
| 7EG9 | Tfiid-based intermediate pic on scp promoter | electron microscopy | u | — | — |
| 7EGA | TFIID-based intermediate PIC on PUMA promoter | electron microscopy | u | — | — |
| 7EGA | Tfiid-based intermediate pic on puma promoter | electron microscopy | u | — | — |
| 7EGB | TFIID-based holo PIC on SCP promoter | electron microscopy | u | — | 1 (best 0.82) |
| 7EGC | p53-bound TFIID-based holo PIC on HDM2 promoter | electron microscopy | u | — | — |
| 7ENA | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | electron microscopy | PG | — | — |
| 7ENC | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | electron microscopy | PG | — | — |
| 7F4G | Structure of RPAP2-bound RNA polymerase II | electron microscopy | G | — | — |
| 7UNC | Pol II-DSIF-SPT6-PAF1c-TFIIS complex with rewrapped nucleosome | electron microscopy | G | — | 2 (best 0.78) |
| 7UND | Pol II-DSIF-SPT6-PAF1c-TFIIS-nucleosome complex (stalled at +38) | electron microscopy | G | — | 2 (best 0.77) |
| 7YCX | The structure of INTAC-PEC complex | electron microscopy | k | — | 1 (best 0.81) |
| 8A3Y | Structure of mammalian Pol II-DSIF-SPT6-PAF1-TFIIS-hexasome elongation complex | electron microscopy | G | — | 2 (best 0.78) |
| 8A40 | Structure of mammalian Pol II-TFIIS elongation complex | electron microscopy | G | — | 2 (best 0.78) |
| 8BVW | RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W) | electron microscopy | G | — | 1 (best 0.80) |
| 8BYQ | RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W) | electron microscopy | G | — | 2 (best 0.81) |
| 8GXQ | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | electron microscopy | PG | — | 1 (best 0.81) |
| 8OEU | Structure of the mammalian Pol II-SPT6 complex (composite structure, Structure 4) | electron microscopy | G | — | 4 (best 0.80) |
| 8OF0 | Structure of the mammalian Pol II-SPT6-Elongin complex, Structure 1 | electron microscopy | G | — | 2 (best 0.85) |
| 8P4A | Structural insights into human co-transcriptional capping - structure 1 | electron microscopy | G | — | 2 (best 0.79) |
| 8P4C | Structural insights into human co-transcriptional capping - structure 3 | electron microscopy | G | — | 2 (best 0.77) |
| 8P4D | Structural insights into human co-transcriptional capping - structure 4 | electron microscopy | G | — | 3 (best 0.78) |
| 8P4E | Structural insights into human co-transcriptional capping - structure 5 | electron microscopy | G | — | 3 (best 0.74) |
| 8P4F | Structural insights into human co-transcriptional capping - structure 6 | electron microscopy | G | — | 4 (best 0.81) |
| 8RBX | Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex | electron microscopy | G | — | 1 (best 0.83) |
| 8S51 | RNA polymerase II core initially transcribing complex with an ordered RNA of 8 nt | electron microscopy | G | — | 1 (best 0.77) |
| 8S5N | RNA polymerase II core initially transcribing complex with an ordered RNA of 12 nt | electron microscopy | G | — | 2 (best 0.81) |
| 8UHG | Structure of paused transcription complex Pol II-DSIF-NELF - poised post-translocated | electron microscopy | G | — | 1 (best 0.70) |
| 8UIS | Structure of transcription complex Pol II-DSIF-NELF-TFIIS | electron microscopy | G | — | 1 (best 0.74) |
| 8W8E | human co-transcriptional RNA capping enzyme RNGTT | electron microscopy | G | — | 1 (best 0.77) |
| 8WAK | Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II… | electron microscopy | u | — | 1 (best 0.79) |
| 8WAO | Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II… | electron microscopy | u | — | 1 (best 0.79) |
| 8WAQ | Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II… | electron microscopy | u | — | — |
| 8WAS | Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II… | electron microscopy | u | — | 1 (best 0.79) |
| 8WAZ | De novo transcribing complex 16 (TC16), the early elongation complex with Pol II positioned 16nt… | electron microscopy | u | — | 2 (best 0.69) |
| 9EGX | RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-hexasome, bp +27 | electron microscopy | G | — | 1 (best 0.79) |
| 9EGY | RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-nucleosome, bp +27 | electron microscopy | G | — | 1 (best 0.79) |
| 9EGZ | RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-nucleosome, bp +27 | electron microscopy | G | — | 1 (best 0.79) |
| 9EH2 | RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-FACT nucleosome upstream | electron microscopy | G | — | 2 (best 0.83) |
| 9FD2 | Structure of Pol II-TC-NER-STK19 complex | electron microscopy | G | — | 1 (best 0.80) |
Elsewhere
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