UniProt O00268
Transcription initiation factor tfiid subunit 4 (O00268)
Transcription initiation factor tfiid subunit 4 (UniProt O00268): 24 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O00268
- Protein
- Transcription initiation factor tfiid subunit 4
- Experimental structures
- 24
- Predicted models
- 1
Structures
25 records of O00268 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1H3O | Crystal Structure of the Human TAF4-TAF12 (TAFII135-TAFII20) Complex | x-ray diffraction | A, C | — | — |
| 1H3O | Crystal structure of the human TAF4-TAF12 (TAFII135-TAFII20) complex | x-ray diffraction | A, C | — | — |
| 2P6V | Structure of TAFH domain of the human TAF4 subunit of TFIID | x-ray diffraction | A | — | — |
| 2P6V | Structure of tafh domain of the human TAF4 subunit of tfiid | x-ray diffraction | A | — | — |
| 6MZC | Human tfiid bc core | electron microscopy | E | — | — |
| 6MZD | Human tfiid lobe a canonical | electron microscopy | D | — | — |
| 6MZL | Human tfiid canonical state | electron microscopy | D, E | — | — |
| 6MZM | Human tfiid bound to promoter DNA and tfiia | electron microscopy | D | — | — |
| 7EDX | P53-bound tfiid-based core pic on HDM2 promoter | electron microscopy | D, d | — | — |
| 7EG7 | Tfiid-based core pic on scp promoter | electron microscopy | D, d | — | — |
| 7EG8 | Tfiid-based core pic on puma promoter | electron microscopy | D, d | — | — |
| 7EG9 | Tfiid-based intermediate pic on scp promoter | electron microscopy | D, d | — | — |
| 7EGA | TFIID-based intermediate PIC on PUMA promoter | electron microscopy | D, d | — | — |
| 7EGA | Tfiid-based intermediate pic on puma promoter | electron microscopy | D, d | — | — |
| 7EGC | p53-bound TFIID-based holo PIC on HDM2 promoter | electron microscopy | D, d | — | — |
| 7EGD | Scp promoter-bound tfiid-tfiia in initial tbp-loading state | electron microscopy | D, d | — | — |
| 7EGE | Tfiid in canonical conformation | electron microscopy | D, d | — | — |
| 7EGF | TFIID lobe A subcomplex | electron microscopy | d | — | — |
| 7EGF | Tfiid lobe a subcomplex | electron microscopy | d | — | — |
| 7EGG | Tfiid lobe B subcomplex | electron microscopy | D | — | — |
| 7EGI | Tfiid in rearranged conformation | electron microscopy | D, d | — | — |
| 7EGJ | Scp promoter-bound tfiid-tfiia in post tbp-loading state | electron microscopy | D, d | — | — |
| 7ENA | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | electron microscopy | DD, Dd | — | — |
| 7ENC | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | electron microscopy | DD, Dd | — | — |
| O00268 | AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 4 (O00268) | predicted | A | — | — |
Experiment against prediction
- 2P6V chain A against the predicted model O00268: TM-score 0.98, RMSD 0.98 Å
- 2P6V chain A against the predicted model O00268: TM-score 0.98, RMSD 0.98 Å
- 1H3O chain A against the predicted model O00268: TM-score 0.83, RMSD 1.05 Å
- 1H3O chain A against the predicted model O00268: TM-score 0.83, RMSD 1.05 Å
- 6MZC chain E against the predicted model O00268: TM-score 0.62, RMSD 3.62 Å
- 6MZD chain D against the predicted model O00268: TM-score 0.61, RMSD 3.67 Å
- 6MZL chain D against the predicted model O00268: TM-score 0.61, RMSD 3.67 Å
- 7EGJ chain D against the predicted model O00268: TM-score 0.58, RMSD 4.33 Å
- 7EGD chain d against the predicted model O00268: TM-score 0.58, RMSD 3.35 Å
- 7ENC chain Dd against the predicted model O00268: TM-score 0.57, RMSD 3.44 Å
Elsewhere
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