UniProt A0A4X1VTX4
DNA-directed RNA polymerase II subunit E (A0A4X1VTX4)
DNA-directed RNA polymerase II subunit E (UniProt A0A4X1VTX4): 46 experimental structures on GenesisL1, 79 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A4X1VTX4
- Protein
- DNA-directed RNA polymerase II subunit E
- Experimental structures
- 46
- Predicted models
- 0
- Pockets
- 79 · 37 records with a druggable one
Structures
46 records of A0A4X1VTX4 in the MolNFT archive: 46 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7EDX | p53-bound TFIID-based core PIC on HDM2 promoter | electron microscopy | s | — | 1 (best 0.82) |
| 7EDX | P53-bound tfiid-based core pic on HDM2 promoter | electron microscopy | s | — | — |
| 7EGA | TFIID-based intermediate PIC on PUMA promoter | electron microscopy | s | — | — |
| 7EGA | Tfiid-based intermediate pic on puma promoter | electron microscopy | s | — | — |
| 7EGB | TFIID-based holo PIC on SCP promoter | electron microscopy | s | — | 1 (best 0.80) |
| 7EGC | p53-bound TFIID-based holo PIC on HDM2 promoter | electron microscopy | s | — | — |
| 7ENA | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | electron microscopy | PE | — | — |
| 7ENC | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | electron microscopy | PE | — | — |
| 7F4G | Structure of RPAP2-bound RNA polymerase II | electron microscopy | E | — | 3 (best 0.76) |
| 7F4G | Structure of RPAP2-bound RNA polymerase II | electron microscopy | E | — | — |
| 7UNC | Pol II-DSIF-SPT6-PAF1c-TFIIS complex with rewrapped nucleosome | electron microscopy | E | — | 3 (best 0.79) |
| 7UND | Pol II-DSIF-SPT6-PAF1c-TFIIS-nucleosome complex (stalled at +38) | electron microscopy | E | — | 1 (best 0.78) |
| 7YCX | The structure of INTAC-PEC complex | electron microscopy | 4 | — | 1 (best 0.80) |
| 8A40 | Structure of mammalian Pol II-TFIIS elongation complex | electron microscopy | E | — | 4 (best 0.80) |
| 8GXQ | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | electron microscopy | PE | — | — |
| 8GXS | PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state | electron microscopy | PE | — | — |
| 8UHA | Structure of paused transcription complex Pol II-DSIF-NELF - tilted | electron microscopy | E | — | 3 (best 0.79) |
| 8UHD | Structure of paused transcription complex Pol II-DSIF-NELF - post-translocated | electron microscopy | E | — | 2 (best 0.77) |
| 8UHG | Structure of paused transcription complex Pol II-DSIF-NELF - poised post-translocated | electron microscopy | E | — | 2 (best 0.77) |
| 8UI0 | Structure of poised transcription complex Pol II-DSIF-NELF - pre-translocated | electron microscopy | E | — | 2 (best 0.79) |
| 8UIS | Structure of transcription complex Pol II-DSIF-NELF-TFIIS | electron microscopy | E | — | 3 (best 0.79) |
| 8W8E | human co-transcriptional RNA capping enzyme RNGTT | electron microscopy | E | — | 5 (best 0.81) |
| 8W8F | human co-transcriptional RNA capping enzyme RNGTT-CMTR1 | electron microscopy | E | — | 3 (best 0.81) |
| 8WAK | Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II… | electron microscopy | s | — | 1 (best 0.78) |
| 8WAL | Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II… | electron microscopy | s | — | 1 (best 0.79) |
| 8WAN | Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II… | electron microscopy | s | — | 2 (best 0.80) |
| 8WAO | Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II… | electron microscopy | s | — | 1 (best 0.78) |
| 8WAP | Structure of transcribing complex 6 (TC6), the initially transcribing complex with Pol II… | electron microscopy | s | — | 1 (best 0.79) |
| 8WAQ | Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II… | electron microscopy | s | — | 1 (best 0.79) |
| 8WAR | Structure of transcribing complex 8 (TC8), the initially transcribing complex with Pol II… | electron microscopy | s | — | 1 (best 0.78) |
| 8WAS | Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II… | electron microscopy | s | — | 1 (best 0.79) |
| 8WAT | De novo transcribing complex 10 (TC10), the early elongation complex with Pol II positioned 10nt… | electron microscopy | s | — | 3 (best 0.78) |
| 8WAU | De novo transcribing complex 11 (TC11), the early elongation complex with Pol II positioned 11nt… | electron microscopy | s | — | 2 (best 0.78) |
| 8WAV | De novo transcribing complex 12 (TC12), the early elongation complex with Pol II positioned 12nt… | electron microscopy | s | — | 2 (best 0.79) |
| 8WAW | De novo transcribing complex 13 (TC13), the early elongation complex with Pol II positioned 13nt… | electron microscopy | s | — | 2 (best 0.78) |
| 8WAX | De novo transcribing complex 14 (TC14), the early elongation complex with Pol II positioned 14nt… | electron microscopy | s | — | 3 (best 0.81) |
| 8WAY | De novo transcribing complex 15 (TC15), the early elongation complex with Pol II positioned 15nt… | electron microscopy | s | — | 2 (best 0.78) |
| 8WAZ | De novo transcribing complex 16 (TC16), the early elongation complex with Pol II positioned 16nt… | electron microscopy | s | — | 2 (best 0.78) |
| 8WB0 | De novo transcribing complex 17 (TC17), the early elongation complex with Pol II positioned 17nt… | electron microscopy | s | — | 2 (best 0.78) |
| 9BZ0 | Structure of an STK19-containing TC-NER complex | electron microscopy | E | — | 2 (best 0.81) |
| 9EGX | RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-hexasome, bp +27 | electron microscopy | E | — | 2 (best 0.81) |
| 9EGY | RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-nucleosome, bp +27 | electron microscopy | E | — | 3 (best 0.81) |
| 9EGZ | RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-nucleosome, bp +27 | electron microscopy | E | — | 3 (best 0.81) |
| 9EH0 | RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-nucleosome, 30 bp upstream | electron microscopy | E | — | 3 (best 0.81) |
| 9EH1 | RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-nucleosome, 20 bp upstream | electron microscopy | E | — | 3 (best 0.80) |
| 9EH2 | RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-FACT nucleosome upstream | electron microscopy | E | — | 2 (best 0.78) |
Elsewhere
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