GL1X · GenesisL1 explorer

UniProt A0A4X1TRS6

RPB12 (A0A4X1TRS6)

RPB12 (UniProt A0A4X1TRS6): 51 experimental structures on GenesisL1, 1 ligand bound, 65 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A4X1TRS6
Protein
RPB12
Experimental structures
51
Predicted models
0
Ligands
1
Pockets
65 · 39 records with a druggable one

Structures

51 records of A0A4X1TRS6 in the MolNFT archive: 51 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7EDXp53-bound TFIID-based core PIC on HDM2 promoterelectron microscopyzZN2 (best 0.86)
7EDXP53-bound tfiid-based core pic on HDM2 promoterelectron microscopyzZN—
7EG7TFIID-based core PIC on SCP promoterelectron microscopyzZN1 (best 0.77)
7EG7Tfiid-based core pic on scp promoterelectron microscopyzZN—
7EG8TFIID-based core PIC on PUMA promoterelectron microscopyzZN2 (best 0.84)
7EG8Tfiid-based core pic on puma promoterelectron microscopyzZN—
7EG9TFIID-based intermediate PIC on SCP promoterelectron microscopyzZN1 (best 0.78)
7EG9Tfiid-based intermediate pic on scp promoterelectron microscopyzZN—
7EGATFIID-based intermediate PIC on PUMA promoterelectron microscopyzZN—
7EGATfiid-based intermediate pic on puma promoterelectron microscopyzZN—
7EGBTFIID-based holo PIC on SCP promoterelectron microscopyzZN1 (best 0.77)
7EGCp53-bound TFIID-based holo PIC on HDM2 promoterelectron microscopyzZN—
7ENATFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED)electron microscopyPLZN—
7ENCTFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED)electron microscopyPLZN—
7F4GStructure of RPAP2-bound RNA polymerase IIelectron microscopyLZN2 (best 0.80)
7F4GStructure of RPAP2-bound RNA polymerase IIelectron microscopyLZN—
7UNCPol II-DSIF-SPT6-PAF1c-TFIIS complex with rewrapped nucleosomeelectron microscopyL—2 (best 0.86)
7UNDPol II-DSIF-SPT6-PAF1c-TFIIS-nucleosome complex (stalled at +38)electron microscopyL—2 (best 0.84)
7YCXThe structure of INTAC-PEC complexelectron microscopyaZN2 (best 0.87)
8GXQPIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding stateelectron microscopyPLZN—
8GXSPIC-Mediator in complex with +1 nucleosome (T40N) in H-binding stateelectron microscopyPLZN—
8UHAStructure of paused transcription complex Pol II-DSIF-NELF - tiltedelectron microscopyLZN2 (best 0.86)
8UHDStructure of paused transcription complex Pol II-DSIF-NELF - post-translocatedelectron microscopyLZN2 (best 0.85)
8UHGStructure of paused transcription complex Pol II-DSIF-NELF - poised post-translocatedelectron microscopyLZN2 (best 0.85)
8UI0Structure of poised transcription complex Pol II-DSIF-NELF - pre-translocatedelectron microscopyLZN2 (best 0.85)
8UISStructure of transcription complex Pol II-DSIF-NELF-TFIISelectron microscopyLZN3 (best 0.86)
8W8Ehuman co-transcriptional RNA capping enzyme RNGTTelectron microscopyLZN2 (best 0.85)
8W8Fhuman co-transcriptional RNA capping enzyme RNGTT-CMTR1electron microscopyLZN2 (best 0.87)
8WAKStructure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II…electron microscopyzZN2 (best 0.81)
8WALStructure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II…electron microscopyzZN2 (best 0.87)
8WANStructure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II…electron microscopyzZN2 (best 0.79)
8WAOStructure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II…electron microscopyzZN1 (best 0.78)
8WAPStructure of transcribing complex 6 (TC6), the initially transcribing complex with Pol II…electron microscopyzZN1 (best 0.77)
8WAQStructure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II…electron microscopyzZN1 (best 0.79)
8WARStructure of transcribing complex 8 (TC8), the initially transcribing complex with Pol II…electron microscopyzZN1 (best 0.78)
8WASStructure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II…electron microscopyzZN2 (best 0.78)
8WATDe novo transcribing complex 10 (TC10), the early elongation complex with Pol II positioned 10nt…electron microscopyzZN1 (best 0.78)
8WAUDe novo transcribing complex 11 (TC11), the early elongation complex with Pol II positioned 11nt…electron microscopyzZN1 (best 0.78)
8WAVDe novo transcribing complex 12 (TC12), the early elongation complex with Pol II positioned 12nt…electron microscopyzZN1 (best 0.78)
8WAWDe novo transcribing complex 13 (TC13), the early elongation complex with Pol II positioned 13nt…electron microscopyzZN1 (best 0.78)
8WAXDe novo transcribing complex 14 (TC14), the early elongation complex with Pol II positioned 14nt…electron microscopyzZN1 (best 0.78)
8WAYDe novo transcribing complex 15 (TC15), the early elongation complex with Pol II positioned 15nt…electron microscopyzZN1 (best 0.78)
8WAZDe novo transcribing complex 16 (TC16), the early elongation complex with Pol II positioned 16nt…electron microscopyzZN1 (best 0.78)
8WB0De novo transcribing complex 17 (TC17), the early elongation complex with Pol II positioned 17nt…electron microscopyzZN1 (best 0.78)
9BZ0Structure of an STK19-containing TC-NER complexelectron microscopyLZN1 (best 0.81)
9EGXRNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-hexasome, bp +27electron microscopyLZN3 (best 0.84)
9EGYRNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-nucleosome, bp +27electron microscopyLZN3 (best 0.86)
9EGZRNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-nucleosome, bp +27electron microscopyLZN2 (best 0.84)
9EH0RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-nucleosome, 30 bp upstreamelectron microscopyLZN2 (best 0.84)
9EH2RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-FACT nucleosome upstreamelectron microscopyLZN2 (best 0.84)
9FD2Structure of Pol II-TC-NER-STK19 complexelectron microscopyLZN2 (best 0.89)

Ligands

  • ZN · Zinc ion · in 49 records

Elsewhere

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.