UniProt P49848
Transcription initiation factor TFIID subunit 6 (P49848)
Transcription initiation factor TFIID subunit 6 (UniProt P49848): 43 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 164 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P49848
- Protein
- Transcription initiation factor TFIID subunit 6
- Experimental structures
- 43
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 164 · 20 records with a druggable one
Structures
44 records of P49848 in the MolNFT archive: 43 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5FUR | Structure of human TFIID-IIA bound to core promoter DNA | electron microscopy | J, K | — | 1 (best 0.75) |
| 5FUR | Structure of human tfiid-iia bound to core promoter DNA | electron microscopy | J, K | — | — |
| 6F3T | Crystal structure of the human TAF5-TAF6-TAF9 complex | x-ray diffraction | E, G, I, K | CL | 13 (best 0.86) |
| 6F3T | Crystal structure of the human TAF5-TAF6-TAF9 complex | x-ray diffraction | E, G, I, K | CL | — |
| 6MZC | Human TFIID BC core | electron microscopy | H, I | — | 11 (best 0.87) |
| 6MZC | Human tfiid bc core | electron microscopy | H, I | — | — |
| 6MZD | Human TFIID Lobe A canonical | electron microscopy | H | — | 10 (best 0.87) |
| 6MZD | Human tfiid lobe a canonical | electron microscopy | H | — | — |
| 6MZL | Human TFIID canonical state | electron microscopy | H, I | — | 11 (best 0.89) |
| 6MZL | Human tfiid canonical state | electron microscopy | H, I | — | — |
| 6MZM | Human TFIID bound to promoter DNA and TFIIA | electron microscopy | H, I | — | 9 (best 0.88) |
| 6MZM | Human tfiid bound to promoter DNA and tfiia | electron microscopy | H, I | — | — |
| 7EDX | p53-bound TFIID-based core PIC on HDM2 promoter | electron microscopy | F, f | — | 7 (best 0.86) |
| 7EDX | P53-bound tfiid-based core pic on HDM2 promoter | electron microscopy | F, f | — | — |
| 7EG7 | TFIID-based core PIC on SCP promoter | electron microscopy | F, f | — | 8 (best 0.87) |
| 7EG7 | Tfiid-based core pic on scp promoter | electron microscopy | F, f | — | — |
| 7EG8 | Tfiid-based core pic on puma promoter | electron microscopy | F, f | — | — |
| 7EG9 | TFIID-based intermediate PIC on SCP promoter | electron microscopy | F, f | — | 7 (best 0.88) |
| 7EG9 | Tfiid-based intermediate pic on scp promoter | electron microscopy | F, f | — | — |
| 7EGA | TFIID-based intermediate PIC on PUMA promoter | electron microscopy | F, f | — | — |
| 7EGA | Tfiid-based intermediate pic on puma promoter | electron microscopy | F, f | — | — |
| 7EGB | TFIID-based holo PIC on SCP promoter | electron microscopy | F, f | — | 8 (best 0.86) |
| 7EGC | p53-bound TFIID-based holo PIC on HDM2 promoter | electron microscopy | F, f | — | — |
| 7EGD | Scp promoter-bound tfiid-tfiia in initial tbp-loading state | electron microscopy | F, f | — | — |
| 7EGE | TFIID in canonical conformation | electron microscopy | F, f | — | 13 (best 0.87) |
| 7EGE | Tfiid in canonical conformation | electron microscopy | F, f | — | — |
| 7EGF | TFIID lobe A subcomplex | electron microscopy | f | — | — |
| 7EGF | Tfiid lobe a subcomplex | electron microscopy | f | — | — |
| 7EGG | TFIID lobe B subcomplex | electron microscopy | F | — | 6 (best 0.86) |
| 7EGG | Tfiid lobe B subcomplex | electron microscopy | F | — | — |
| 7EGH | Tfiid lobe C subcomplex | electron microscopy | F, f | — | — |
| 7EGI | TFIID in rearranged conformation | electron microscopy | F, f | — | 12 (best 0.86) |
| 7EGI | Tfiid in rearranged conformation | electron microscopy | F, f | — | — |
| 7EGJ | Scp promoter-bound tfiid-tfiia in post tbp-loading state | electron microscopy | F, f | — | — |
| 7ENA | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | electron microscopy | DF, Df | — | — |
| 7ENC | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | electron microscopy | DF, Df | — | — |
| 8GXQ | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | electron microscopy | Df, DF | — | 6 (best 0.86) |
| 8WAK | Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II… | electron microscopy | F, f | — | 7 (best 0.86) |
| 8WAL | Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II… | electron microscopy | F, f | — | 7 (best 0.87) |
| 8WAO | Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II… | electron microscopy | F, f | — | 6 (best 0.87) |
| 8WAQ | Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II… | electron microscopy | F, f | — | 8 (best 0.86) |
| 8WAR | Structure of transcribing complex 8 (TC8), the initially transcribing complex with Pol II… | electron microscopy | F, f | — | 7 (best 0.87) |
| 8WAS | Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II… | electron microscopy | F, f | — | 6 (best 0.87) |
| P49848 | AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 6 (P49848) | predicted | A | — | 1 (best 0.49) |
Ligands
- CL · Chloride ion · in 2 records
Experiment against prediction
- 7EGH chain f against the predicted model P49848: TM-score 0.96, RMSD 1.26 Å
- 6MZC chain H against the predicted model P49848: TM-score 0.95, RMSD 1.45 Å
- 6MZC chain H against the predicted model P49848: TM-score 0.95, RMSD 1.45 Å
- 6MZM chain H against the predicted model P49848: TM-score 0.95, RMSD 1.47 Å
- 6MZM chain H against the predicted model P49848: TM-score 0.95, RMSD 1.47 Å
- 7EGF chain f against the predicted model P49848: TM-score 0.92, RMSD 1.39 Å
- 7EGF chain f against the predicted model P49848: TM-score 0.92, RMSD 1.39 Å
- 5FUR chain J against the predicted model P49848: TM-score 0.91, RMSD 2.11 Å
- 5FUR chain J against the predicted model P49848: TM-score 0.91, RMSD 2.11 Å
- 7EGH chain F against the predicted model P49848: TM-score 0.91, RMSD 1.83 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.