MolNFT v1 · #457068 · protein
AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 6 (P49848)
P49848: “AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 6 (P49848)”. 1 pocket (best druggability 0.49). MolNFT v1 #457068 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P49848
- Type
- protein
- Length
- 677 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xEa58c7534E5701aA8370E0fAEb19b7e14653e69c
- Molecule
- Transcription initiation factor tfiid subunit 6
- UniProt
- P49848
- Pockets
- 1 · best druggability 0.49
Structure
1 distinct chain · 40% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcription initiation factor tfiid subunit 6 | protein | 677 | 40% helix, 2% strand | P49848 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 238 | 0.49 | 0.74 | 22 | empty |
Compared structures
- 6MZC · Human TFIID BC core · an experimental structure of the same protein · chain A against I, TM-score 0.38
- 6MZL · Human TFIID canonical state · an experimental structure of the same protein · chain A against I, TM-score 0.38
- 6MZC · Human tfiid bc core · an experimental structure of the same protein · chain A against I, TM-score 0.38
- 6MZL · Human tfiid canonical state · an experimental structure of the same protein · chain A against I, TM-score 0.38
- 6MZM · Human tfiid bound to promoter DNA and tfiia · an experimental structure of the same protein · chain A against I, TM-score 0.38
- 6MZM · Human TFIID bound to promoter DNA and TFIIA · an experimental structure of the same protein · chain A against I, TM-score 0.38
- 7EG9 · Tfiid-based intermediate pic on scp promoter · an experimental structure of the same protein · chain A against f, TM-score 0.38
- 7EG9 · TFIID-based intermediate PIC on SCP promoter · an experimental structure of the same protein · chain A against f, TM-score 0.38
- 7EG8 · Tfiid-based core pic on puma promoter · an experimental structure of the same protein · chain A against f, TM-score 0.38
- 7EG8 · TFIID-based core PIC on PUMA promoter · an experimental structure of the same protein · chain A against f, TM-score 0.38
- 7EG7 · Tfiid-based core pic on scp promoter · an experimental structure of the same protein · chain A against f, TM-score 0.38
- 7EG7 · TFIID-based core PIC on SCP promoter · an experimental structure of the same protein · chain A against f, TM-score 0.38
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49848
- Elsewhere: UniProt P49848 · AlphaFold DB P49848
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