UniProt P52655
Transcription initiation factor IIA subunit 1 (P52655)
Transcription initiation factor IIA subunit 1 (UniProt P52655): 61 experimental structures on GenesisL1, 30 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P52655
- Protein
- Transcription initiation factor IIA subunit 1
- Experimental structures
- 61
- Predicted models
- 0
- Pockets
- 30 · 17 records with a druggable one
Structures
61 records of P52655 in the MolNFT archive: 61 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1NVP | Human TFIIA/TBP/DNA complex | x-ray diffraction | B, C | — | — |
| 1NVP | Human TFIIA/TBP/DNA complex | x-ray diffraction | B, C | — | — |
| 5FUR | Structure of human TFIID-IIA bound to core promoter DNA | electron microscopy | B, C | — | 1 (best 0.70) |
| 5FUR | Structure of human tfiid-iia bound to core promoter DNA | electron microscopy | B, C | — | — |
| 5IY6 | Human holo-PIC in the closed state | electron microscopy | N | — | — |
| 5IY6 | Human holo-pic in the closed state | electron microscopy | N | — | — |
| 5IY7 | Human holo-pic in the open state | electron microscopy | N | — | — |
| 5IY8 | Human holo-pic in the initial transcribing state | electron microscopy | N | — | — |
| 5IY9 | Human holo-PIC in the initial transcribing state (no IIS) | electron microscopy | N | — | — |
| 5IY9 | Human holo-pic in the initial transcribing state (no iis) | electron microscopy | N | — | — |
| 5IYA | Human core-PIC in the closed state | electron microscopy | N | — | — |
| 5IYA | Human core-pic in the closed state | electron microscopy | N | — | — |
| 5IYB | Human core-PIC in the open state | electron microscopy | N | — | — |
| 5IYB | Human core-pic in the open state | electron microscopy | N | — | — |
| 5IYC | Human core-PIC in the initial transcribing state | electron microscopy | N | — | 1 (best 0.82) |
| 5IYC | Human core-pic in the initial transcribing state | electron microscopy | N | — | — |
| 5IYD | Human core-PIC in the initial transcribing state (no IIS) | electron microscopy | N | — | — |
| 5IYD | Human core-pic in the initial transcribing state (no iis) | electron microscopy | N | — | — |
| 5M4S | Transcription factor TFIIA as a single chain protein | x-ray diffraction | A | — | — |
| 5M4S | Transcription factor tfiia as a single chain protein | x-ray diffraction | A | — | — |
| 6O9L | Human holo-pic in the closed state | electron microscopy | N | — | — |
| 7EDX | p53-bound TFIID-based core PIC on HDM2 promoter | electron microscopy | Q | — | — |
| 7EDX | P53-bound tfiid-based core pic on HDM2 promoter | electron microscopy | Q | — | — |
| 7EG7 | Tfiid-based core pic on scp promoter | electron microscopy | Q | — | — |
| 7EG8 | Tfiid-based core pic on puma promoter | electron microscopy | Q | — | — |
| 7EG9 | Tfiid-based intermediate pic on scp promoter | electron microscopy | Q | — | — |
| 7EGA | TFIID-based intermediate PIC on PUMA promoter | electron microscopy | Q | — | — |
| 7EGA | Tfiid-based intermediate pic on puma promoter | electron microscopy | Q | — | — |
| 7EGB | TFIID-based holo PIC on SCP promoter | electron microscopy | Q | — | — |
| 7EGC | p53-bound TFIID-based holo PIC on HDM2 promoter | electron microscopy | Q | — | — |
| 7EGD | Scp promoter-bound tfiid-tfiia in initial tbp-loading state | electron microscopy | Q | — | — |
| 7EGI | TFIID in rearranged conformation | electron microscopy | Q | — | 2 (best 0.66) |
| 7EGI | Tfiid in rearranged conformation | electron microscopy | Q | — | — |
| 7EGJ | Scp promoter-bound tfiid-tfiia in post tbp-loading state | electron microscopy | Q | — | — |
| 7NVR | Human Mediator with RNA Polymerase II Pre-initiation complex | electron microscopy | U | — | — |
| 7NVR | Human mediator with RNA polymerase II pre-initiation complex | electron microscopy | U | — | — |
| 7NVS | RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | U | — | 3 (best 0.83) |
| 7NVS | RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | U | — | — |
| 7NVT | RNA polymerase II core pre-initiation complex with closed promoter DNA in distal position | electron microscopy | U | — | 2 (best 0.83) |
| 7NVT | RNA polymerase II core pre-initiation complex with closed promoter DNA in distal position | electron microscopy | U | — | — |
| 7NVU | RNA polymerase II core pre-initiation complex with open promoter DNA | electron microscopy | U | — | 2 (best 0.80) |
| 7NVU | RNA polymerase II core pre-initiation complex with open promoter DNA | electron microscopy | U | — | — |
| 7NVY | RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | U | — | — |
| 7NVZ | RNA polymerase II pre-initiation complex with closed promoter DNA in distal position | electron microscopy | U | — | — |
| 7NW0 | RNA polymerase II pre-initiation complex with open promoter DNA | electron microscopy | U | — | 2 (best 0.80) |
| 7NW0 | RNA polymerase II pre-initiation complex with open promoter DNA | electron microscopy | U | — | — |
| 7ZWC | Structure of SNAPc:TBP-TFIIA-TFIIB sub-complex bound to U5 snRNA promoter | electron microscopy | U | — | 3 (best 0.76) |
| 7ZX7 | Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC) | electron microscopy | U | — | 2 (best 0.85) |
| 7ZX8 | Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC) | electron microscopy | U | — | 1 (best 0.79) |
| 7ZXE | Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC) | electron microscopy | U | — | 5 (best 0.77) |
| 8BVW | RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W) | electron microscopy | U | — | — |
| 8BYQ | RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W) | electron microscopy | U | — | 1 (best 0.81) |
| 8BZ1 | RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W) | electron microscopy | U | — | — |
| 8GXQ | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | electron microscopy | DQ | — | 1 (best 0.81) |
| 8S51 | RNA polymerase II core initially transcribing complex with an ordered RNA of 8 nt | electron microscopy | U | — | 1 (best 0.77) |
| 8S5N | RNA polymerase II core initially transcribing complex with an ordered RNA of 12 nt | electron microscopy | U | — | 1 (best 0.80) |
| 8WAK | Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II… | electron microscopy | Q | — | 1 (best 0.79) |
| 8WAO | Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II… | electron microscopy | Q | — | — |
| 8WAQ | Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II… | electron microscopy | Q | — | 1 (best 0.80) |
| 8WAS | Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II… | electron microscopy | Q | — | — |
1 record more on the page itself.
Elsewhere
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