MolNFT v1 · #183598 · protein + DNA
RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position
7NVY: “RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position”. Electron microscopy, 3 ligands (SF4, ZN, MG). MolNFT v1 #183598 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7NVY
- Type
- protein + DNA
- Length
- 8,218 residues
- Chains
- 32
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P18074, P32780, Q92759, P51948, Q13889, Q6ZYL4, Q13888, P19447, I3LGP4, I3LCH3, A0A287ADR4, I3LSI7, F1SKN8, I3LJZ9, A0A4X1ULF2, P60899, A0A4X1VYD0, A0A4X1UK25, I3LN51, Q00403, P20226, P35269, P13984, P52655, P52657, P29083, P29084
- Ligands
- SF4, ZN, MG
Structure
electron microscopy · 32 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| 0 | — | protein | 714 | — | P18074 |
| 1 | — | protein | 265 | — | P32780 |
| 2 | — | protein | 390 | — | Q92759 |
| 3 | — | protein | 149 | — | P51948 |
| 4 | — | protein | 263 | — | Q13889 |
| 5 | — | protein | 66 | — | Q6ZYL4 |
| 6 | — | protein | 347 | — | Q13888 |
| 7 | — | protein | 605 | — | P19447 |
| A | — | protein | 1423 | — | — |
| B | — | protein | 1136 | — | I3LGP4 |
| C | — | protein | 257 | — | I3LCH3 |
| D | — | protein | 128 | — | A0A287ADR4 |
| E | — | protein | 209 | — | I3LSI7 |
| F | — | protein | 79 | — | F1SKN8 |
| G | — | protein | 171 | — | I3LJZ9 |
| H | — | protein | 148 | — | A0A4X1ULF2 |
| I | — | protein | 114 | — | P60899 |
| J | — | protein | 64 | — | A0A4X1VYD0 |
| K | — | protein | 115 | — | A0A4X1UK25 |
| L | — | protein | 44 | — | I3LN51 |
| M | — | protein | 252 | — | Q00403 |
| N | — | dna | 64 | — | — |
| O | — | protein | 179 | — | P20226 |
| Q | — | protein | 138 | — | P35269 |
| R | — | protein | 222 | — | P13984 |
| T | — | dna | 64 | — | — |
| U | — | protein | 113 | — | P52655 |
| V | — | protein | 99 | — | P52657 |
| W | — | protein | 202 | — | P29083 |
| X | — | protein | 171 | — | P29084 |
| Y | — | protein | 19 | — | — |
| Z | — | protein | 8 | — | — |
Ligands and binding sites
- SF4 · Iron/sulfur cluster · ligand · chains 0
- ZN · Zinc ion · metal · 17 copies · chains 3, 4, 6, A, B, C, I, J, L, M, W
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7NVY · RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P18074
- Every structure of UniProt P32780
- Every structure of UniProt Q92759
- Every structure of UniProt P51948
- Every structure of UniProt Q13889
- Every structure of UniProt Q6ZYL4
- Every structure of UniProt Q13888
- Every structure of UniProt P19447
- Every structure of UniProt I3LGP4
- Every structure of UniProt I3LCH3
- Every structure of UniProt A0A287ADR4
- Every structure of UniProt I3LSI7
- Every structure of UniProt F1SKN8
- Every structure of UniProt I3LJZ9
- Every structure of UniProt A0A4X1ULF2
- Every structure of UniProt P60899
- Every structure of UniProt A0A4X1VYD0
- Every structure of UniProt A0A4X1UK25
- Every structure of UniProt I3LN51
- Every structure of UniProt Q00403
- Every structure of UniProt P20226
- Every structure of UniProt P35269
- Every structure of UniProt P13984
- Every structure of UniProt P52655
- Every structure of UniProt P52657
- Every structure of UniProt P29083
- Every structure of UniProt P29084
- Elsewhere: RCSB PDB 7NVY · PDBe 7NVY · UniProt P18074 · UniProt P32780 · UniProt Q92759 · UniProt P51948 · UniProt Q13889 · UniProt Q6ZYL4 · UniProt Q13888 · UniProt P19447 · UniProt I3LGP4 · UniProt I3LCH3 · UniProt A0A287ADR4 · UniProt I3LSI7 · UniProt F1SKN8 · UniProt I3LJZ9 · UniProt A0A4X1ULF2 · UniProt P60899 · UniProt A0A4X1VYD0 · UniProt A0A4X1UK25 · UniProt I3LN51 · UniProt Q00403 · UniProt P20226 · UniProt P35269 · UniProt P13984 · UniProt P52655 · UniProt P52657 · UniProt P29083 · UniProt P29084
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