UniProt Q92759
General transcription factor IIH subunit 4, p52 (Q92759)
General transcription factor IIH subunit 4, p52 (UniProt Q92759): 29 experimental structures on GenesisL1, 7 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q92759
- Protein
- General transcription factor IIH subunit 4, p52
- Experimental structures
- 29
- Predicted models
- 0
- Pockets
- 7 · 2 records with a druggable one
Structures
29 records of Q92759 in the MolNFT archive: 29 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5IVW | Human core tfiih bound to DNA within the pic | electron microscopy | 2 | — | — |
| 5IY6 | Human holo-pic in the closed state | electron microscopy | 2 | — | — |
| 5IY7 | Human holo-pic in the open state | electron microscopy | 2 | — | — |
| 5IY8 | Human holo-pic in the initial transcribing state | electron microscopy | 2 | — | — |
| 5IY9 | Human holo-PIC in the initial transcribing state (no IIS) | electron microscopy | 2 | — | — |
| 5IY9 | Human holo-pic in the initial transcribing state (no iis) | electron microscopy | 2 | — | — |
| 5OF4 | The cryo-EM structure of human tfiih | electron microscopy | D | — | — |
| 6NMI | Cryo-EM structure of the human TFIIH core complex | electron microscopy | D | — | — |
| 6NMI | Cryo-EM structure of the human tfiih core complex | electron microscopy | D | — | — |
| 6O9L | Human holo-pic in the closed state | electron microscopy | 2 | — | — |
| 6O9M | Structure of the human apo tfiih | electron microscopy | 2 | — | — |
| 6RO4 | Structure of the core TFIIH-XPA-DNA complex | electron microscopy | C | — | — |
| 6RO4 | Structure of the core tfiih-xpa-DNA complex | electron microscopy | C | — | — |
| 7AD8 | Core tfiih-xpa-DNA complex with modelled P62 subunit | electron microscopy | C | — | — |
| 7EGC | p53-bound TFIID-based holo PIC on HDM2 promoter | electron microscopy | 4 | — | — |
| 7ENA | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | electron microscopy | 4 | — | — |
| 7ENC | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | electron microscopy | 4 | — | — |
| 7NVR | Human Mediator with RNA Polymerase II Pre-initiation complex | electron microscopy | 2 | — | — |
| 7NVR | Human mediator with RNA polymerase II pre-initiation complex | electron microscopy | 2 | — | — |
| 7NVV | XPB-containing part of TFIIH in a post-translocated state (with ADP-BeF3) | electron microscopy | 2 | — | — |
| 7NVV | Xpb-containing part of tfiih in a post-translocated state (with ADP- BEF3) | electron microscopy | 2 | — | — |
| 7NVW | Tfiih in a pre-translocated state (without ADP-BEF3) | electron microscopy | 2 | — | — |
| 7NVX | Tfiih in a post-translocated state (with ADP-BEF3) | electron microscopy | 2 | — | — |
| 7NVY | RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | 2 | — | — |
| 7NVZ | RNA polymerase II pre-initiation complex with closed promoter DNA in distal position | electron microscopy | 2 | — | — |
| 7NW0 | RNA polymerase II pre-initiation complex with open promoter DNA | electron microscopy | 2 | — | — |
| 8EBU | XPC release from Core7-XPA-DNA (Cy5) | electron microscopy | D | — | 4 (best 0.83) |
| 8EBW | Initial DNA-lesion (AP) binding by XPC and TFIIH complex2 | electron microscopy | D | — | 3 (best 0.78) |
| Q92759 | AlphaFold monomer V2.0 prediction for general transcription factor iih subunit 4 (Q92759) | — | — | — |
Elsewhere
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