UniProt I3LCH3
DNA-directed RNA polymerase II subunit RPB3 (I3LCH3)
DNA-directed RNA polymerase II subunit RPB3 (UniProt I3LCH3): 34 experimental structures on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- I3LCH3
- Protein
- DNA-directed RNA polymerase II subunit RPB3
- Experimental structures
- 34
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 8 · 2 records with a druggable one
Structures
34 records of I3LCH3 in the MolNFT archive: 34 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6EXV | Structure of mammalian RNA polymerase II elongation complex inhibited by alpha-amanitin | electron microscopy | C | ZN | — |
| 6GMH | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 | electron microscopy | C | ZN | — |
| 6GMH | Structure of activated transcription complex pol II-dsif-paf-SPT6 | electron microscopy | C | ZN | — |
| 6GML | Structure of paused transcription complex pol II-dsif-nelf | electron microscopy | C | ZN | — |
| 6TED | Structure of complete, activated transcription complex pol II-dsif- paf-SPT6 uncovers allosteric… | electron microscopy | C | ZN | — |
| 7B0Y | Structure of a transcribing RNA polymerase II-U1 snrnp complex | electron microscopy | C | ZN | — |
| 7B7U | Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2 | electron microscopy | C | ZN | — |
| 7EDX | P53-bound tfiid-based core pic on HDM2 promoter | electron microscopy | q | ZN | — |
| 7EG7 | Tfiid-based core pic on scp promoter | electron microscopy | q | ZN | — |
| 7EG8 | Tfiid-based core pic on puma promoter | electron microscopy | q | ZN | — |
| 7EG9 | Tfiid-based intermediate pic on scp promoter | electron microscopy | q | ZN | — |
| 7EGC | p53-bound TFIID-based holo PIC on HDM2 promoter | electron microscopy | q | ZN | — |
| 7ENA | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | electron microscopy | PC | ZN | — |
| 7ENC | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | electron microscopy | PC | ZN | — |
| 7F4G | Structure of RPAP2-bound RNA polymerase II | electron microscopy | C | — | — |
| 7NVR | Human Mediator with RNA Polymerase II Pre-initiation complex | electron microscopy | C | ZN | — |
| 7NVR | Human mediator with RNA polymerase II pre-initiation complex | electron microscopy | C | ZN | — |
| 7NVS | RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | C | ZN | — |
| 7NVT | RNA polymerase II core pre-initiation complex with closed promoter DNA in distal position | electron microscopy | C | ZN | — |
| 7NVU | RNA polymerase II core pre-initiation complex with open promoter DNA | electron microscopy | C | ZN | — |
| 7NVY | RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | C | ZN | — |
| 7NVZ | RNA polymerase II pre-initiation complex with closed promoter DNA in distal position | electron microscopy | C | ZN | — |
| 7NW0 | RNA polymerase II pre-initiation complex with open promoter DNA | electron microscopy | C | ZN | — |
| 7OKX | Structure of active transcription elongation complex pol II-dsif (SPT5-KOW5)-ELL2-EAF1 (composite… | electron microscopy | C | ZN | — |
| 7OKY | Structure of active transcription elongation complex pol II-dsif-ELL2- EAF1(COMPOSITE structure) | electron microscopy | C | ZN | — |
| 7OL0 | Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5) | electron microscopy | C | ZN | 5 (best 0.87) |
| 7OL0 | Structure of active transcription elongation complex pol II-dsif (SPT5-KOW5) | electron microscopy | C | ZN | — |
| 7OO3 | Pol II-csb-csa-DDB1-uvssa (STRUCTURE1) | electron microscopy | C | ZN | — |
| 7OOB | Pol II-CSB-CSA-DDB1-UVSSA-ADPBeF3 (Structure2) | electron microscopy | C | ZN | 3 (best 0.83) |
| 7OOB | Pol II-csb-csa-DDB1-uvssa-ADPBEF3 (STRUCTURE2) | electron microscopy | C | ZN | — |
| 7OOP | Pol II-csb-csa-DDB1-uvssa-paf-SPT6 (structure 3) | electron microscopy | C | ZN | — |
| 7OPC | Pol II-csb-CRL4CSA-uvssa-SPT6-paf (structure 4) | electron microscopy | C | ZN | — |
| 7OPD | Pol II-csb-CRL4CSA-uvssa-SPT6-paf (structure 5) | electron microscopy | C | ZN | — |
| 8BZ1 | RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W) | electron microscopy | C | ZN | — |
Ligands
- ZN · Zinc ion · in 33 records
Elsewhere
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