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UniProt P35269

General transcription factor IIF subunit 1 (P35269)

General transcription factor IIF subunit 1 (UniProt P35269): 61 experimental structures on GenesisL1, 44 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P35269
Protein
General transcription factor IIF subunit 1
Experimental structures
61
Predicted models
0
Pockets
44 · 16 records with a druggable one

Structures

61 records of P35269 in the MolNFT archive: 61 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
1F3UCrystal structure of the RAP30/74 interaction domains of human tfiifx-ray diffractionB, D, F, H——
1F3UCrystal structure of the RAP30/74 interaction domains of human tfiifx-ray diffractionB, D, F, H——
1I27Crystal structure of the C-terminal domain of the RAP74 subunit of human transcription factor iif…x-ray diffractionA——
1I27Crystal structure of the C-terminal domain of the RAP74 subunit of human transcription factor iif…x-ray diffractionA——
1J2XCrystal structure of RAP74 C-terminal domain complexed with FCP1 C-terminal peptidex-ray diffractionA——
1J2XCrystal structure of RAP74 C-terminal domain complexed with FCP1 C- terminal peptidex-ray diffractionA——
1NHASolution Structure of the Carboxyl-Terminal Domain of RAP74 and NMR Characterization of the…solution nmrA——
1NHASolution structure of the carboxyl-terminal domain of RAP74 and NMR characterization of the…solution nmrA——
1ONVNMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNAP II CTD Phosphatase FCP1solution nmrA——
1ONVNMR structure of a complex containing the tfiif subunit RAP74 and the rnap II ctd phosphatase FCP1solution nmrA——
2K7LNMR structure of a complex formed by the C-terminal domain of human RAP74 and a phosphorylated…solution nmrA——
2K7LNMR structure of a complex formed by the C-terminal domain of human RAP74 and a phosphorylated…solution nmrA——
5IY6Human holo-PIC in the closed stateelectron microscopyS—2 (best 0.83)
5IY6Human holo-pic in the closed stateelectron microscopyS——
5IY7Human holo-pic in the open stateelectron microscopyS——
5IY8Human holo-pic in the initial transcribing stateelectron microscopyS——
5IY9Human holo-PIC in the initial transcribing state (no IIS)electron microscopyS——
5IY9Human holo-pic in the initial transcribing state (no iis)electron microscopyS——
5IYAHuman core-PIC in the closed stateelectron microscopyS——
5IYAHuman core-pic in the closed stateelectron microscopyS——
5IYBHuman core-PIC in the open stateelectron microscopyS—3 (best 0.83)
5IYBHuman core-pic in the open stateelectron microscopyS——
5IYCHuman core-PIC in the initial transcribing stateelectron microscopyS—3 (best 0.82)
5IYCHuman core-pic in the initial transcribing stateelectron microscopyS——
5IYDHuman core-PIC in the initial transcribing state (no IIS)electron microscopyS——
5IYDHuman core-pic in the initial transcribing state (no iis)electron microscopyS——
6O9LHuman holo-pic in the closed stateelectron microscopyS——
7EDXp53-bound TFIID-based core PIC on HDM2 promoterelectron microscopyS—2 (best 0.80)
7EDXP53-bound tfiid-based core pic on HDM2 promoterelectron microscopyS——
7EG7Tfiid-based core pic on scp promoterelectron microscopyS——
7EG8Tfiid-based core pic on puma promoterelectron microscopyS——
7EG9Tfiid-based intermediate pic on scp promoterelectron microscopyS——
7EGATFIID-based intermediate PIC on PUMA promoterelectron microscopyS——
7EGATfiid-based intermediate pic on puma promoterelectron microscopyS——
7EGBTFIID-based holo PIC on SCP promoterelectron microscopyS——
7EGCp53-bound TFIID-based holo PIC on HDM2 promoterelectron microscopyS——
7ENATFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED)electron microscopyFA——
7ENCTFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED)electron microscopyFA——
7NVRHuman Mediator with RNA Polymerase II Pre-initiation complexelectron microscopyQ——
7NVRHuman mediator with RNA polymerase II pre-initiation complexelectron microscopyQ——
7NVSRNA polymerase II core pre-initiation complex with closed promoter DNA in proximal positionelectron microscopyQ—3 (best 0.81)
7NVSRNA polymerase II core pre-initiation complex with closed promoter DNA in proximal positionelectron microscopyQ——
7NVTRNA polymerase II core pre-initiation complex with closed promoter DNA in distal positionelectron microscopyQ—3 (best 0.80)
7NVTRNA polymerase II core pre-initiation complex with closed promoter DNA in distal positionelectron microscopyQ——
7NVURNA polymerase II core pre-initiation complex with open promoter DNAelectron microscopyQ—3 (best 0.81)
7NVURNA polymerase II core pre-initiation complex with open promoter DNAelectron microscopyQ——
7NVYRNA polymerase II pre-initiation complex with closed promoter DNA in proximal positionelectron microscopyQ——
7NVZRNA polymerase II pre-initiation complex with closed promoter DNA in distal positionelectron microscopyQ——
7NW0RNA polymerase II pre-initiation complex with open promoter DNAelectron microscopyQ—3 (best 0.81)
7NW0RNA polymerase II pre-initiation complex with open promoter DNAelectron microscopyQ——
7ZX8Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC)electron microscopyQ—3 (best 0.81)
8BVWRNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W)electron microscopyQ—3 (best 0.80)
8BYQRNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W)electron microscopyQ—3 (best 0.82)
8BZ1RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W)electron microscopyQ——
8GXQPIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding stateelectron microscopyFA——
8S51RNA polymerase II core initially transcribing complex with an ordered RNA of 8 ntelectron microscopyQ—2 (best 0.80)
8WAKStructure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II…electron microscopyS—2 (best 0.80)
8WAOStructure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II…electron microscopyS—3 (best 0.80)
8WAQStructure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II…electron microscopyS—3 (best 0.80)
8WAZDe novo transcribing complex 16 (TC16), the early elongation complex with Pol II positioned 16nt…electron microscopyS—3 (best 0.82)

1 record more on the page itself.

Elsewhere

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