MolNFT v2 · #205433 · protein + DNA
RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W)
8BZ1: “RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W)”. Electron microscopy at 3.8, 2 ligands (ZN, MG). MolNFT v2 #205433 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 8BZ1
- Type
- protein + DNA
- Length
- 6,063 residues
- Chains
- 28
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.8
- Source
- Homo sapiens; Sus scrofa; Xenopus laevis; SYNTHETIC CONSTRUCT
- UniProt
- A0A8D1DPV6, I3LGP4, I3LCH3, A0A287ADR4, I3LSI7, F1SKN8, I3LJZ9, I3LCB2, P60899, A0A4X1VYD0, F1RKE4, I3LN51, Q00403, P20226, P35269, P13984, P52655, P52657, P84233, P62799, P06897, P02281
- Ligands
- ZN, MG
Structure
electron microscopy · resolution 3.8 · 27 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 1423 | — | A0A8D1DPV6 |
| B | — | protein | 1136 | — | I3LGP4 |
| C | — | protein | 257 | — | I3LCH3 |
| D | — | protein | 128 | — | A0A287ADR4 |
| E | — | protein | 209 | — | I3LSI7 |
| F | — | protein | 89 | — | F1SKN8 |
| G | — | protein | 171 | — | I3LJZ9 |
| H | — | protein | 148 | — | I3LCB2 |
| I | — | protein | 114 | — | P60899 |
| J | — | protein | 64 | — | A0A4X1VYD0 |
| K | — | protein | 115 | — | F1RKE4 |
| L | — | protein | 44 | — | I3LN51 |
| M | — | protein | 252 | — | Q00403 |
| N | — | dna | 198 | — | — |
| O | — | protein | 179 | — | P20226 |
| Q | — | protein | 138 | — | P35269 |
| R | — | protein | 222 | — | P13984 |
| T | — | dna | 198 | — | — |
| U | — | protein | 113 | — | P52655 |
| V | — | protein | 99 | — | P52657 |
| a | — | protein | 97 | — | P84233 |
| b, f | — | protein | 82 | — | P62799 |
| c | — | protein | 109 | — | P06897 |
| d | — | protein | 97 | — | P02281 |
| e | — | protein | 98 | — | P84233 |
| g | — | protein | 106 | — | P06897 |
| h | — | protein | 95 | — | P02281 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- P84233 · AlphaFold monomer V2.0 prediction for histone H3.2 (P84233) · a predicted model of the same protein · chain e against A, TM-score 0.99
- P62799 · AlphaFold monomer V2.0 prediction for histone H4 (P62799) · a predicted model of the same protein · chain b against A, TM-score 0.97
- P06897 · AlphaFold monomer V2.0 prediction for histone H2A type 1 (P06897) · a predicted model of the same protein · chain g against A, TM-score 0.96
- P60899 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB9 (P60899) · a predicted model of the same protein · chain I against A, TM-score 0.87
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A8D1DPV6
- Every structure of UniProt I3LGP4
- Every structure of UniProt I3LCH3
- Every structure of UniProt A0A287ADR4
- Every structure of UniProt I3LSI7
- Every structure of UniProt F1SKN8
- Every structure of UniProt I3LJZ9
- Every structure of UniProt I3LCB2
- Every structure of UniProt P60899
- Every structure of UniProt A0A4X1VYD0
- Every structure of UniProt F1RKE4
- Every structure of UniProt I3LN51
- Every structure of UniProt Q00403
- Every structure of UniProt P20226
- Every structure of UniProt P35269
- Every structure of UniProt P13984
- Every structure of UniProt P52655
- Every structure of UniProt P52657
- Every structure of UniProt P84233
- Every structure of UniProt P62799
- Every structure of UniProt P06897
- Every structure of UniProt P02281
- Elsewhere: RCSB PDB 8BZ1 · PDBe 8BZ1 · UniProt A0A8D1DPV6 · UniProt I3LGP4 · UniProt I3LCH3 · UniProt A0A287ADR4 · UniProt I3LSI7 · UniProt F1SKN8 · UniProt I3LJZ9 · UniProt I3LCB2 · UniProt P60899 · UniProt A0A4X1VYD0 · UniProt F1RKE4 · UniProt I3LN51 · UniProt Q00403 · UniProt P20226 · UniProt P35269 · UniProt P13984 · UniProt P52655 · UniProt P52657 · UniProt P84233 · UniProt P62799 · UniProt P06897 · UniProt P02281
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.