UniProt P06897
Histone H2A type 1 (P06897)
Histone H2A type 1 (UniProt P06897): 123 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 369 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P06897
- Protein
- Histone H2A type 1
- Experimental structures
- 123
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 369 · 41 records with a druggable one
Structures
124 records of P06897 in the MolNFT archive: 123 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AOI | Complex between nucleosome core particle (H3,H4,H2A,H2B) and 146 bp long DNA fragment | x-ray diffraction | C, G | — | — |
| 1AOI | Complex between nucleosome core particle (H3,H4,H2A,H2B) and 146 bp long DNA fragment | x-ray diffraction | C, G | — | — |
| 1KX3 | X-Ray Structure of the Nucleosome Core Particle, NCP146, at 2.0 A Resolution | x-ray diffraction | C, G | — | — |
| 1KX3 | X-ray structure of the nucleosome core particle, NCP146, at 2.0 a resolution | x-ray diffraction | C, G | — | — |
| 1KX4 | X-Ray Structure of the Nucleosome Core Particle, NCP146b, at 2.6 A Resolution | x-ray diffraction | C, G | — | — |
| 1KX4 | X-ray structure of the nucleosome core particle, NCP146B, at 2.6 a resolution | x-ray diffraction | C, G | — | — |
| 1KX5 | X-Ray Structure of the Nucleosome Core Particle, NCP147, at 1.9 A Resolution | x-ray diffraction | C, G | — | — |
| 1KX5 | X-ray structure of the nucleosome core particle, NCP147, at 1.9 a resolution | x-ray diffraction | C, G | — | — |
| 1M18 | Ligand binding alters the structure and dynamics of nucleosomal DNA | x-ray diffraction | C, G | — | — |
| 1M18 | Ligand binding alters the structure and dynamics of nucleosomal DNA | x-ray diffraction | C, G | — | — |
| 1M19 | Ligand binding alters the structure and dynamics of nucleosomal DNA | x-ray diffraction | C, G | — | — |
| 1M19 | Ligand binding alters the structure and dynamics of nucleosomal DNA | x-ray diffraction | C, G | — | — |
| 1M1A | Ligand binding alters the structure and dynamics of nucleosomal DNA | x-ray diffraction | C, G | — | — |
| 1M1A | Ligand binding alters the structure and dynamics of nucleosomal DNA | x-ray diffraction | C, G | — | — |
| 1ZBB | Structure of the 4_601_167 Tetranucleosome | x-ray diffraction | C, G, c, g | — | — |
| 1ZBB | Structure of the 4_601_167 tetranucleosome | x-ray diffraction | C, G, c, g | — | — |
| 3C1B | The effect of H3 K79 dimethylation and H4 K20 trimethylation on nucleosome and chromatin structure | x-ray diffraction | C, G | — | — |
| 3C1B | The effect of H3 K79 dimethylation and H4 K20 trimethylation on nucleosome and chromatin structure | x-ray diffraction | C, G | — | — |
| 3C1C | The effect of H3 K79 dimethylation and H4 K20 trimethylation on nucleosome and chromatin structure | x-ray diffraction | C, G | — | — |
| 3C1C | The effect of H3 K79 dimethylation and H4 K20 trimethylation on nucleosome and chromatin structure | x-ray diffraction | C, G | — | — |
| 3O62 | Nucleosome core particle modified with a cisplatin 1,3-cis-{Pt(NH3)2}2+-d(GpTpG) intrastrand… | x-ray diffraction | C, G | — | — |
| 3O62 | Nucleosome core particle modified with a cisplatin 1,3-cis-{PT(NH3) 2}2+-D(GPTPG) intrastrand… | x-ray diffraction | C, G | — | — |
| 3REH | 2.5 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 145 bp… | x-ray diffraction | C, G | — | — |
| 3REH | 2.5 ångström crystal structure of the nucleosome core particle assembled with a 145 bp… | x-ray diffraction | C, G | — | — |
| 3REI | 2.65 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 145 bp… | x-ray diffraction | C, G | — | — |
| 3REI | 2.65 ångström crystal structure of the nucleosome core particle assembled with a 145 bp… | x-ray diffraction | C, G | — | — |
| 3REJ | 2.55 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp… | x-ray diffraction | C, G | — | — |
| 3REJ | 2.55 ångström crystal structure of the nucleosome core particle assembled with a 146 bp… | x-ray diffraction | C, G | — | — |
| 3REK | 2.6 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp… | x-ray diffraction | C, G | — | — |
| 3REK | 2.6 ångström crystal structure of the nucleosome core particle assembled with a 146 bp… | x-ray diffraction | C, G | — | — |
| 3REL | 2.7 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp… | x-ray diffraction | C, G | — | — |
| 3REL | 2.7 ångström crystal structure of the nucleosome core particle assembled with a 146 bp… | x-ray diffraction | C, G | — | — |
| 4J8U | X-ray structure of NCP145 with chlorido(eta-6-p-cymene)(N-phenyl-2-pyridinecarbothioamide)osmium(II) | x-ray diffraction | C, G | — | — |
| 4J8U | X-ray structure of NCP145 with CHLORIDO(ETA-6-P-CYMENE)(N-phenyl-2… | x-ray diffraction | C, G | — | — |
| 4WU8 | Structure of trptnap-NCP145 | x-ray diffraction | C, G | — | — |
| 4WU9 | Structure of cisptnap-NCP145 | x-ray diffraction | C, G | — | — |
| 4ZUX | Saga dub module UBP8/SGF11/SUS1/SGF73 bound to ubiqitinated nucleosome | x-ray diffraction | C, G, M, Q | — | — |
| 5F99 | X-ray Structure of the MMTV-A Nucleosome Core Particle | x-ray diffraction | C, G | CL | 12 (best 0.80) |
| 5F99 | X-ray structure of the mmtv-a nucleosome core particle | x-ray diffraction | C, G | — | — |
| 5G2E | Structure of the NAP1 H2A H2B complex | x-ray diffraction | C, G, K, O, S, W | — | — |
| 5MLU | Crystal structure of the PFV GAG CBS bound to a mononucleosome | x-ray diffraction | C, G | — | 12 (best 0.81) |
| 5MLU | Crystal structure of the pfv gag cbs bound to a mononucleosome | x-ray diffraction | C, G | — | — |
| 5NL0 | Crystal structure of a 197-bp palindromic 601L nucleosome in complex with linker histone H1 | x-ray diffraction | C, G, M | — | — |
| 5NL0 | Crystal structure of a 197-bp palindromic 601L nucleosome in complex with linker histone H1 | x-ray diffraction | C, G, M | — | — |
| 6FTX | Structure of the chromatin remodelling enzyme CHD1 bound to a ubiquitinylated nucleosome | electron microscopy | C, G | — | — |
| 6G0L | Structure of two molecules of the chromatin remodelling enzyme Chd1 bound to a nucleosome | electron microscopy | C, G | — | 7 (best 0.80) |
| 6G0L | Structure of two molecules of the chromatin remodelling enzyme CHD1 bound to a nucleosome | electron microscopy | C, G | — | — |
| 6I84 | Structure of transcribing RNA polymerase II-nucleosome complex | electron microscopy | Q, V | — | — |
| 6LTJ | Structure of nucleosome-bound human BAF complex | electron microscopy | C, G | — | 6 (best 0.81) |
| 6LTJ | Structure of nucleosome-bound human baf complex | electron microscopy | C, G | — | — |
| 6NE3 | Cryo-EM structure of singly-bound SNF2H-nucleosome complex with SNF2H bound at shl-2 | electron microscopy | C, G | — | — |
| 6NJ9 | Active state Dot1L bound to the H2B-Ubiquitinated nucleosome, 2-to-1 complex | electron microscopy | C, G | — | 10 (best 0.82) |
| 6NJ9 | Active state DOT1L bound to the H2B-ubiquitinated nucleosome, 2-to-1 complex | electron microscopy | C, G | — | — |
| 6NN6 | Structure of DOT1L-H2BK120UB nucleosome complex | electron microscopy | C, G | — | — |
| 6NOG | Poised-state DOT1L bound to the H2B-ubiquitinated nucleosome | electron microscopy | C, G | — | — |
| 6NQA | Active state Dot1L bound to the H2B-Ubiquitinated nucleosome, 1-to-1 complex | electron microscopy | G, C | — | 11 (best 0.83) |
| 6NQA | Active state DOT1L bound to the H2B-ubiquitinated nucleosome, 1-to-1 complex | electron microscopy | G, C | — | — |
| 6PA7 | The cryo-EM structure of the human DNMT3A2-DNMT3B3 complex bound to nucleosome. | electron microscopy | C, G | CL | — |
| 6PWV | Cryo-EM structure of MLL1 core complex bound to the nucleosome | electron microscopy | I, M | — | — |
| 6PWW | Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome | electron microscopy | I, M | — | 11 (best 0.82) |
64 records more on the page itself.
Ligands
Experiment against prediction
- 6LTJ chain G against the predicted model P06897: TM-score 0.98, RMSD 0.49 Å
- 6LTJ chain G against the predicted model P06897: TM-score 0.98, RMSD 0.49 Å
- 5G2E chain C against the predicted model P06897: TM-score 0.98, RMSD 0.54 Å
- 6LTJ chain C against the predicted model P06897: TM-score 0.97, RMSD 0.59 Å
- 6LTJ chain C against the predicted model P06897: TM-score 0.97, RMSD 0.59 Å
- 9EGY chain g against the predicted model P06897: TM-score 0.97, RMSD 0.71 Å
- 9GD2 chain G against the predicted model P06897: TM-score 0.97, RMSD 0.64 Å
- 9GD1 chain G against the predicted model P06897: TM-score 0.97, RMSD 0.68 Å
- 3C1B chain G against the predicted model P06897: TM-score 0.96, RMSD 0.75 Å
- 3C1B chain G against the predicted model P06897: TM-score 0.96, RMSD 0.75 Å
Elsewhere
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