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Ligand · PT

PT · Platinum (II) ion

PT, Platinum (II) ion (Pt +2, 195.1 g/mol), in the MolNFT structures on GenesisL1: bound in 92 records (69 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
PT
Formula
Pt +2
Class
metal
Structures
92
PDB entries
69

Binding sites

PT in 92 structures; the first of them:

  • 5DJL · Structure of WT Human Glutathione Transferase in complex with cisplatin in the presence… · PT A302 · binds CYS101, CYS101
  • 5DJM · Structure of WT Human Glutathione Transferase in complex with cisplatin in the absence of… · PT A302 · binds CYS101, CYS101
  • 5DLB · Crystal structure of chaperone EspG3 of ESX-3 type VII secretion system from… · PT A306
  • 5E5E · X-ray structure of the adduct formed in the reaction between RNase A and a neutral… · PT A201 · binds HIS105
  • 5FM0 · Crystal structure of the 6-carboxyhexanoate-CoA ligase (BioW)from Bacillus subtilis… · PT A1260 · binds MET16
  • 5HLL · Re-refinement of 4g4a: room-temperature X-ray diffraction study of cisplatin and its… · PT A205 · binds HIS15
  • 5HMV · Re refinement of 4mwk. · PT A207 · binds ARG14, HIS15
  • 5I5Q · Re refinement of 4mwn. · PT A203 · binds ARG14, HIS15
  • 5IDD · Comment on S. W. M. Tanley and J. R. Helliwell Structural dynamics of cisplatin binding… · PT A207 · binds HIS15, ASN93, LYS96
  • 5IHG · The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme a… · PT A202 · binds HIS15
  • 5L3I · Re-refinement of 4dd6; cisplatin coordination chemistry determination at hen egg white… · PT A203 · binds HIS15, THR89

Residues it binds most

HIS 146, MET 80, CYS 47, LYS 44, ARG 36, ASP 30, ASN 30, THR 23, LEU 20, GLU 19 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion
  • DMS · Dimethyl sulfoxide
  • SO4 · Sulfate ion
  • NA · Sodium ion
  • NH3 · Ammonia
  • NO3 · Nitrate ion
  • GOL · Glycerol
  • CD · Cadmium ion
  • MG · Magnesium ion
  • IOD · Iodide ion
  • CA · Calcium ion
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

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