UniProt I3LSI7
DNA-directed RNA polymerase II subunit E (I3LSI7)
DNA-directed RNA polymerase II subunit E (UniProt I3LSI7): 44 experimental structures on GenesisL1, 32 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- I3LSI7
- Protein
- DNA-directed RNA polymerase II subunit E
- Experimental structures
- 44
- Predicted models
- 0
- Pockets
- 32 · 14 records with a druggable one
Structures
44 records of I3LSI7 in the MolNFT archive: 44 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6EXV | Structure of mammalian RNA polymerase II elongation complex inhibited by alpha-amanitin | electron microscopy | E | — | — |
| 6GMH | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 | electron microscopy | E | — | — |
| 6GMH | Structure of activated transcription complex pol II-dsif-paf-SPT6 | electron microscopy | E | — | — |
| 6GML | Structure of paused transcription complex pol II-dsif-nelf | electron microscopy | E | — | — |
| 6TED | Structure of complete, activated transcription complex pol II-dsif- paf-SPT6 uncovers allosteric… | electron microscopy | E | — | — |
| 7B0Y | Structure of a transcribing RNA polymerase II-U1 snrnp complex | electron microscopy | E | — | — |
| 7B7U | Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2 | electron microscopy | E | — | — |
| 7EG7 | Tfiid-based core pic on scp promoter | electron microscopy | s | — | — |
| 7EG8 | Tfiid-based core pic on puma promoter | electron microscopy | s | — | — |
| 7EG9 | Tfiid-based intermediate pic on scp promoter | electron microscopy | s | — | — |
| 7NVR | Human Mediator with RNA Polymerase II Pre-initiation complex | electron microscopy | E | — | — |
| 7NVR | Human mediator with RNA polymerase II pre-initiation complex | electron microscopy | E | — | — |
| 7NVS | RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | E | — | 2 (best 0.80) |
| 7NVS | RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | E | — | — |
| 7NVT | RNA polymerase II core pre-initiation complex with closed promoter DNA in distal position | electron microscopy | E | — | — |
| 7NVU | RNA polymerase II core pre-initiation complex with open promoter DNA | electron microscopy | E | — | — |
| 7NVY | RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | E | — | — |
| 7NVZ | RNA polymerase II pre-initiation complex with closed promoter DNA in distal position | electron microscopy | E | — | — |
| 7NW0 | RNA polymerase II pre-initiation complex with open promoter DNA | electron microscopy | E | — | 1 (best 0.76) |
| 7NW0 | RNA polymerase II pre-initiation complex with open promoter DNA | electron microscopy | E | — | — |
| 7OKX | Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)-ELL2-EAF1 (composite… | electron microscopy | E | — | 2 (best 0.80) |
| 7OKX | Structure of active transcription elongation complex pol II-dsif (SPT5-KOW5)-ELL2-EAF1 (composite… | electron microscopy | E | — | — |
| 7OKY | Structure of active transcription elongation complex Pol II-DSIF-ELL2-EAF1(composite structure) | electron microscopy | E | — | 2 (best 0.79) |
| 7OKY | Structure of active transcription elongation complex pol II-dsif-ELL2- EAF1(COMPOSITE structure) | electron microscopy | E | — | — |
| 7OL0 | Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5) | electron microscopy | E | — | 3 (best 0.80) |
| 7OL0 | Structure of active transcription elongation complex pol II-dsif (SPT5-KOW5) | electron microscopy | E | — | — |
| 7OO3 | Pol II-csb-csa-DDB1-uvssa (STRUCTURE1) | electron microscopy | E | — | — |
| 7OOB | Pol II-CSB-CSA-DDB1-UVSSA-ADPBeF3 (Structure2) | electron microscopy | E | — | 3 (best 0.80) |
| 7OOB | Pol II-csb-csa-DDB1-uvssa-ADPBEF3 (STRUCTURE2) | electron microscopy | E | — | — |
| 7OOP | Pol II-csb-csa-DDB1-uvssa-paf-SPT6 (structure 3) | electron microscopy | E | — | — |
| 7OPC | Pol II-csb-CRL4CSA-uvssa-SPT6-paf (structure 4) | electron microscopy | E | — | — |
| 7OPD | Pol II-csb-CRL4CSA-uvssa-SPT6-paf (structure 5) | electron microscopy | E | — | — |
| 7OZN | RNA polymerase II dimer (class 1) | electron microscopy | E, Q | — | — |
| 7OZO | RNA polymerase II dimer (class 2) | electron microscopy | E, Q | — | — |
| 7OZP | RNA polymerase II dimer (class 3) | electron microscopy | E, Q | — | — |
| 8A3Y | Structure of mammalian Pol II-DSIF-SPT6-PAF1-TFIIS-hexasome elongation complex | electron microscopy | E | — | 3 (best 0.80) |
| 8BZ1 | RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W) | electron microscopy | E | — | — |
| 8OF0 | Structure of the mammalian Pol II-SPT6-Elongin complex, Structure 1 | electron microscopy | E | — | 2 (best 0.80) |
| 8P4A | Structural insights into human co-transcriptional capping - structure 1 | electron microscopy | E | — | 2 (best 0.77) |
| 8P4D | Structural insights into human co-transcriptional capping - structure 4 | electron microscopy | E | — | 2 (best 0.79) |
| 8P4E | Structural insights into human co-transcriptional capping - structure 5 | electron microscopy | E | — | 2 (best 0.78) |
| 8P4F | Structural insights into human co-transcriptional capping - structure 6 | electron microscopy | E | — | 2 (best 0.77) |
| 8RBX | Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex | electron microscopy | E | — | 2 (best 0.80) |
| 9FD2 | Structure of Pol II-TC-NER-STK19 complex | electron microscopy | E | — | 4 (best 0.80) |
Elsewhere
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