GL1X · GenesisL1 explorer

UniProt A0A8D1DPV6

DNA-directed RNA polymerase subunit (A0A8D1DPV6)

DNA-directed RNA polymerase subunit (UniProt A0A8D1DPV6), EC 2.7.7.6: 31 experimental structures on GenesisL1, 3 ligands bound, 340 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A8D1DPV6
Protein
DNA-directed RNA polymerase subunit
EC
2.7.7.6
Experimental structures
31
Predicted models
0
Ligands
3
Pockets
340 · 31 records with a druggable one

Structures

31 records of A0A8D1DPV6 in the MolNFT archive: 31 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7ZWDStructure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC)electron microscopyAZN, MG10 (best 0.88)
7ZX7Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC)electron microscopyAZN, MG11 (best 0.88)
7ZX8Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC)electron microscopyAZN, MG10 (best 0.83)
8BZ1RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W)electron microscopyAZN, MG9 (best 0.89)
8GXQPIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding stateelectron microscopyPAZN, MG2 (best 0.88)
8GXSPIC-Mediator in complex with +1 nucleosome (T40N) in H-binding stateelectron microscopyPAZN, MG3 (best 0.88)
8QEQRNA polymerase II bound to minimal Alu RNA right arm in the alternative conformationelectron microscopyAZN, MG15 (best 0.88)
8UHAStructure of paused transcription complex Pol II-DSIF-NELF - tiltedelectron microscopyAZN, MG16 (best 0.87)
8UHDStructure of paused transcription complex Pol II-DSIF-NELF - post-translocatedelectron microscopyAZN, MG15 (best 0.88)
8UHGStructure of paused transcription complex Pol II-DSIF-NELF - poised post-translocatedelectron microscopyAZN, MG14 (best 0.88)
8UI0Structure of poised transcription complex Pol II-DSIF-NELF - pre-translocatedelectron microscopyAZN, MG14 (best 0.88)
8UISStructure of transcription complex Pol II-DSIF-NELF-TFIISelectron microscopyAZN, MG13 (best 0.87)
8W8Ehuman co-transcriptional RNA capping enzyme RNGTTelectron microscopyAMG, ZN12 (best 0.85)
8W8Fhuman co-transcriptional RNA capping enzyme RNGTT-CMTR1electron microscopyAMG, ZN14 (best 0.88)
8WAKStructure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II…electron microscopyoW0F, ZN, MG7 (best 0.88)
8WALStructure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II…electron microscopyoW0F, ZN, MG8 (best 0.88)
8WANStructure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II…electron microscopyoZN, MG, W0F7 (best 0.89)
8WAOStructure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II…electron microscopyoZN, MG, W0F9 (best 0.87)
8WAPStructure of transcribing complex 6 (TC6), the initially transcribing complex with Pol II…electron microscopyoZN, MG, W0F6 (best 0.88)
8WAQStructure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II…electron microscopyoZN, MG, W0F7 (best 0.87)
8WARStructure of transcribing complex 8 (TC8), the initially transcribing complex with Pol II…electron microscopyoZN, MG, W0F6 (best 0.89)
8WASStructure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II…electron microscopyoZN, MG, W0F6 (best 0.88)
8WATDe novo transcribing complex 10 (TC10), the early elongation complex with Pol II positioned 10nt…electron microscopyoZN, MG, W0F15 (best 0.89)
8WAUDe novo transcribing complex 11 (TC11), the early elongation complex with Pol II positioned 11nt…electron microscopyoW0F, ZN, MG15 (best 0.88)
8WAVDe novo transcribing complex 12 (TC12), the early elongation complex with Pol II positioned 12nt…electron microscopyoZN, MG, W0F15 (best 0.88)
8WAWDe novo transcribing complex 13 (TC13), the early elongation complex with Pol II positioned 13nt…electron microscopyoZN, MG, W0F14 (best 0.89)
8WAXDe novo transcribing complex 14 (TC14), the early elongation complex with Pol II positioned 14nt…electron microscopyoZN, MG, W0F15 (best 0.88)
8WAYDe novo transcribing complex 15 (TC15), the early elongation complex with Pol II positioned 15nt…electron microscopyoZN, MG, W0F13 (best 0.89)
8WAZDe novo transcribing complex 16 (TC16), the early elongation complex with Pol II positioned 16nt…electron microscopyoZN, MG, W0F14 (best 0.89)
8WB0De novo transcribing complex 17 (TC17), the early elongation complex with Pol II positioned 17nt…electron microscopyoZN, MG, W0F14 (best 0.88)
9FD2Structure of Pol II-TC-NER-STK19 complexelectron microscopyAZN, MG11 (best 0.89)

Ligands

  • MG · Magnesium ion · in 31 records
  • ZN · Zinc ion · in 31 records
  • W0F · [[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate · in 16 records

Elsewhere

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