UniProt I3LN51
RNA polymerase II subunit K (I3LN51)
RNA polymerase II subunit K (UniProt I3LN51): 47 experimental structures on GenesisL1, 1 ligand bound, 37 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- I3LN51
- Protein
- RNA polymerase II subunit K
- Experimental structures
- 47
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 37 · 20 records with a druggable one
Structures
47 records of I3LN51 in the MolNFT archive: 47 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6EXV | Structure of mammalian RNA polymerase II elongation complex inhibited by alpha-amanitin | electron microscopy | L | ZN | — |
| 6GMH | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 | electron microscopy | L | ZN | — |
| 6GMH | Structure of activated transcription complex pol II-dsif-paf-SPT6 | electron microscopy | L | ZN | — |
| 6GML | Structure of paused transcription complex pol II-dsif-nelf | electron microscopy | L | ZN | — |
| 6TED | Structure of complete, activated transcription complex pol II-dsif- paf-SPT6 uncovers allosteric… | electron microscopy | L | ZN | — |
| 7B0Y | Structure of a transcribing RNA polymerase II-U1 snrnp complex | electron microscopy | L | ZN | — |
| 7B7U | Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2 | electron microscopy | L | ZN | — |
| 7NVR | Human Mediator with RNA Polymerase II Pre-initiation complex | electron microscopy | L | ZN | — |
| 7NVR | Human mediator with RNA polymerase II pre-initiation complex | electron microscopy | L | ZN | — |
| 7NVS | RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | L | ZN | 2 (best 0.80) |
| 7NVS | RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | L | ZN | — |
| 7NVT | RNA polymerase II core pre-initiation complex with closed promoter DNA in distal position | electron microscopy | L | ZN | 3 (best 0.80) |
| 7NVT | RNA polymerase II core pre-initiation complex with closed promoter DNA in distal position | electron microscopy | L | ZN | — |
| 7NVU | RNA polymerase II core pre-initiation complex with open promoter DNA | electron microscopy | L | ZN | 2 (best 0.78) |
| 7NVU | RNA polymerase II core pre-initiation complex with open promoter DNA | electron microscopy | L | ZN | — |
| 7NVY | RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | L | ZN | — |
| 7NVZ | RNA polymerase II pre-initiation complex with closed promoter DNA in distal position | electron microscopy | L | ZN | — |
| 7NW0 | RNA polymerase II pre-initiation complex with open promoter DNA | electron microscopy | L | ZN | 2 (best 0.79) |
| 7NW0 | RNA polymerase II pre-initiation complex with open promoter DNA | electron microscopy | L | ZN | — |
| 7OKX | Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)-ELL2-EAF1 (composite… | electron microscopy | L | ZN | 3 (best 0.86) |
| 7OKX | Structure of active transcription elongation complex pol II-dsif (SPT5-KOW5)-ELL2-EAF1 (composite… | electron microscopy | L | ZN | — |
| 7OKY | Structure of active transcription elongation complex Pol II-DSIF-ELL2-EAF1(composite structure) | electron microscopy | L | ZN | 2 (best 0.87) |
| 7OKY | Structure of active transcription elongation complex pol II-dsif-ELL2- EAF1(COMPOSITE structure) | electron microscopy | L | ZN | — |
| 7OL0 | Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5) | electron microscopy | L | ZN | 3 (best 0.85) |
| 7OL0 | Structure of active transcription elongation complex pol II-dsif (SPT5-KOW5) | electron microscopy | L | ZN | — |
| 7OO3 | Pol II-CSB-CSA-DDB1-UVSSA (Structure1) | electron microscopy | L | ZN | 1 (best 0.79) |
| 7OO3 | Pol II-csb-csa-DDB1-uvssa (STRUCTURE1) | electron microscopy | L | ZN | — |
| 7OOB | Pol II-CSB-CSA-DDB1-UVSSA-ADPBeF3 (Structure2) | electron microscopy | L | ZN | 1 (best 0.79) |
| 7OOB | Pol II-csb-csa-DDB1-uvssa-ADPBEF3 (STRUCTURE2) | electron microscopy | L | ZN | — |
| 7OOP | Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3) | electron microscopy | L | ZN | 1 (best 0.79) |
| 7OOP | Pol II-csb-csa-DDB1-uvssa-paf-SPT6 (structure 3) | electron microscopy | L | ZN | — |
| 7OPC | Pol II-csb-CRL4CSA-uvssa-SPT6-paf (structure 4) | electron microscopy | L | ZN | — |
| 7OPD | Pol II-csb-CRL4CSA-uvssa-SPT6-paf (structure 5) | electron microscopy | L | ZN | — |
| 7OZN | RNA polymerase II dimer (class 1) | electron microscopy | L, X | ZN | — |
| 7OZO | RNA polymerase II dimer (class 2) | electron microscopy | L, X | ZN | — |
| 7OZP | RNA polymerase II dimer (class 3) | electron microscopy | L, X | ZN | — |
| 7ZX8 | Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC) | electron microscopy | L | ZN | 2 (best 0.78) |
| 8BVW | RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W) | electron microscopy | L | ZN | 1 (best 0.77) |
| 8BYQ | RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W) | electron microscopy | L | ZN | 1 (best 0.77) |
| 8BZ1 | RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W) | electron microscopy | L | ZN | — |
| 8OEU | Structure of the mammalian Pol II-SPT6 complex (composite structure, Structure 4) | electron microscopy | L | ZN | 2 (best 0.81) |
| 8OF0 | Structure of the mammalian Pol II-SPT6-Elongin complex, Structure 1 | electron microscopy | L | ZN | 1 (best 0.78) |
| 8P4A | Structural insights into human co-transcriptional capping - structure 1 | electron microscopy | L | ZN | 2 (best 0.80) |
| 8P4C | Structural insights into human co-transcriptional capping - structure 3 | electron microscopy | L | — | 2 (best 0.82) |
| 8P4D | Structural insights into human co-transcriptional capping - structure 4 | electron microscopy | L | — | 2 (best 0.83) |
| 8P4E | Structural insights into human co-transcriptional capping - structure 5 | electron microscopy | L | ZN | 2 (best 0.85) |
| 8P4F | Structural insights into human co-transcriptional capping - structure 6 | electron microscopy | L | ZN | 2 (best 0.86) |
Ligands
- ZN · Zinc ion · in 45 records
Elsewhere
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