MolNFT v1 · #148132 · protein + DNA + RNA
Structure of mammalian RNA polymerase II elongation complex inhibited by alpha-amanitin
6EXV: “Structure of mammalian RNA polymerase II elongation complex inhibited by alpha-amanitin”. Electron microscopy, 2 ligands (ZN, MG). MolNFT v1 #148132 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6EXV
- Type
- protein + DNA + RNA
- Length
- 3,980 residues
- Chains
- 16
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- I3LJR4, I3LGP4, I3LCH3, A0A287ADR4, I3LSI7, F1SKN8, I3LJZ9, I3LCB2, P60899, F1RKE4, I3LN51
- Ligands
- ZN, MG
Structure
electron microscopy · 16 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 1428 | — | I3LJR4 |
| B | — | protein | 1134 | — | I3LGP4 |
| C | — | protein | 257 | — | I3LCH3 |
| D | — | protein | 128 | — | A0A287ADR4 |
| E | — | protein | 209 | — | I3LSI7 |
| F | — | protein | 82 | — | F1SKN8 |
| G | — | protein | 171 | — | I3LJZ9 |
| H | — | protein | 148 | — | I3LCB2 |
| I | — | protein | 114 | — | P60899 |
| J | — | protein | 67 | — | — |
| K | — | protein | 115 | — | F1RKE4 |
| L | — | protein | 44 | — | I3LN51 |
| M | — | protein | 8 | — | — |
| N | — | dna | 25 | — | — |
| P | — | rna | 14 | — | — |
| T | — | dna | 36 | — | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6EXV · Structure of mammalian RNA polymerase II elongation complex inhibited by Alpha-amanitin · the same entry in another collection · chain T against T, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I3LJR4
- Every structure of UniProt I3LGP4
- Every structure of UniProt I3LCH3
- Every structure of UniProt A0A287ADR4
- Every structure of UniProt I3LSI7
- Every structure of UniProt F1SKN8
- Every structure of UniProt I3LJZ9
- Every structure of UniProt I3LCB2
- Every structure of UniProt P60899
- Every structure of UniProt F1RKE4
- Every structure of UniProt I3LN51
- Elsewhere: RCSB PDB 6EXV · PDBe 6EXV · UniProt I3LJR4 · UniProt I3LGP4 · UniProt I3LCH3 · UniProt A0A287ADR4 · UniProt I3LSI7 · UniProt F1SKN8 · UniProt I3LJZ9 · UniProt I3LCB2 · UniProt P60899 · UniProt F1RKE4 · UniProt I3LN51
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