UniProt I3LCB2
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (I3LCB2)
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (UniProt I3LCB2): 31 experimental structures on GenesisL1, 31 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- I3LCB2
- Protein
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- Experimental structures
- 31
- Predicted models
- 0
- Pockets
- 31 · 24 records with a druggable one
Structures
31 records of I3LCB2 in the MolNFT archive: 31 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6EXV | Structure of mammalian RNA polymerase II elongation complex inhibited by alpha-amanitin | electron microscopy | H | — | — |
| 6GMH | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 | electron microscopy | H | — | — |
| 6GMH | Structure of activated transcription complex pol II-dsif-paf-SPT6 | electron microscopy | H | — | — |
| 6GML | Structure of paused transcription complex pol II-dsif-nelf | electron microscopy | H | — | — |
| 6TED | Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric… | electron microscopy | H | — | 1 (best 0.89) |
| 6TED | Structure of complete, activated transcription complex pol II-dsif- paf-SPT6 uncovers allosteric… | electron microscopy | H | — | — |
| 7B0Y | Structure of a transcribing RNA polymerase II-U1 snrnp complex | electron microscopy | H | — | — |
| 8A3Y | Structure of mammalian Pol II-DSIF-SPT6-PAF1-TFIIS-hexasome elongation complex | electron microscopy | H | — | 1 (best 0.88) |
| 8A40 | Structure of mammalian Pol II-TFIIS elongation complex | electron microscopy | H | — | 1 (best 0.89) |
| 8BVW | RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W) | electron microscopy | H | — | 1 (best 0.88) |
| 8BYQ | RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W) | electron microscopy | H | — | 1 (best 0.89) |
| 8BZ1 | RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W) | electron microscopy | H | — | — |
| 8OEU | Structure of the mammalian Pol II-SPT6 complex (composite structure, Structure 4) | electron microscopy | H | — | 2 (best 0.87) |
| 8OF0 | Structure of the mammalian Pol II-SPT6-Elongin complex, Structure 1 | electron microscopy | H | — | 1 (best 0.87) |
| 8P4A | Structural insights into human co-transcriptional capping - structure 1 | electron microscopy | H | — | 2 (best 0.84) |
| 8P4B | Structural insights into human co-transcriptional capping - structure 2 | electron microscopy | H | — | 1 (best 0.84) |
| 8P4C | Structural insights into human co-transcriptional capping - structure 3 | electron microscopy | H | — | 1 (best 0.84) |
| 8P4D | Structural insights into human co-transcriptional capping - structure 4 | electron microscopy | H | — | 1 (best 0.84) |
| 8P4E | Structural insights into human co-transcriptional capping - structure 5 | electron microscopy | H | — | 1 (best 0.84) |
| 8P4F | Structural insights into human co-transcriptional capping - structure 6 | electron microscopy | H | — | 1 (best 0.88) |
| 8RBX | Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex | electron microscopy | H | — | 1 (best 0.88) |
| 8S51 | RNA polymerase II core initially transcribing complex with an ordered RNA of 8 nt | electron microscopy | H | — | 1 (best 0.79) |
| 8S5N | RNA polymerase II core initially transcribing complex with an ordered RNA of 12 nt | electron microscopy | H | — | 1 (best 0.87) |
| 8W8E | human co-transcriptional RNA capping enzyme RNGTT | electron microscopy | H | — | 2 (best 0.83) |
| 8WAK | Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II… | electron microscopy | v | — | 1 (best 0.88) |
| 8WAO | Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II… | electron microscopy | v | — | 2 (best 0.86) |
| 8WAQ | Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II… | electron microscopy | v | — | 1 (best 0.86) |
| 8WAS | Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II… | electron microscopy | v | — | 1 (best 0.88) |
| 8WAT | De novo transcribing complex 10 (TC10), the early elongation complex with Pol II positioned 10nt… | electron microscopy | v | — | 3 (best 0.87) |
| 8WAZ | De novo transcribing complex 16 (TC16), the early elongation complex with Pol II positioned 16nt… | electron microscopy | v | — | 2 (best 0.88) |
| 9FD2 | Structure of Pol II-TC-NER-STK19 complex | electron microscopy | H | — | 1 (best 0.89) |
Elsewhere
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