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UniProt I3LJR4

DNA-directed RNA polymerase subunit (I3LJR4)

DNA-directed RNA polymerase subunit (UniProt I3LJR4), EC 2.7.7.6: 6 experimental structures on GenesisL1, 2 ligands bound, 27 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
I3LJR4
Protein
DNA-directed RNA polymerase subunit
EC
2.7.7.6
Experimental structures
6
Predicted models
0
Ligands
2
Pockets
27 · 3 records with a druggable one

Structures

6 records of I3LJR4 in the MolNFT archive: 6 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6EXVStructure of mammalian RNA polymerase II elongation complex inhibited by Alpha-amanitinelectron microscopyAZN, MG15 (best 0.87)
6EXVStructure of mammalian RNA polymerase II elongation complex inhibited by alpha-amanitinelectron microscopyAZN, MG—
7B7UCryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2electron microscopyA—11 (best 0.87)
7B7UCryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2electron microscopyA——
7PKSStructural basis of Integrator-mediated transcription regulationelectron microscopyM——
8RBZStructure of Integrator-PP2A-SOSS-CTD post-termination complexelectron microscopyY—1 (best 0.89)

Ligands

  • MG · Magnesium ion · in 2 records
  • ZN · Zinc ion · in 2 records

Elsewhere

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