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UniProt F1RKE4

DNA-directed RNA polymerase II subunit RPB11-a (F1RKE4)

DNA-directed RNA polymerase II subunit RPB11-a (UniProt F1RKE4): 23 experimental structures on GenesisL1, 34 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
F1RKE4
Protein
DNA-directed RNA polymerase II subunit RPB11-a
Experimental structures
23
Predicted models
0
Pockets
34 · 16 records with a druggable one

Structures

23 records of F1RKE4 in the MolNFT archive: 23 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6EXVStructure of mammalian RNA polymerase II elongation complex inhibited by alpha-amanitinelectron microscopyK——
6GMHStructure of activated transcription complex Pol II-DSIF-PAF-SPT6electron microscopyK——
6GMHStructure of activated transcription complex pol II-dsif-paf-SPT6electron microscopyK——
6GMLStructure of paused transcription complex pol II-dsif-nelfelectron microscopyK——
6TEDStructure of complete, activated transcription complex pol II-dsif- paf-SPT6 uncovers allosteric…electron microscopyK——
7B0YStructure of a transcribing RNA polymerase II-U1 snrnp complexelectron microscopyK——
8A3YStructure of mammalian Pol II-DSIF-SPT6-PAF1-TFIIS-hexasome elongation complexelectron microscopyK—2 (best 0.88)
8A40Structure of mammalian Pol II-TFIIS elongation complexelectron microscopyK—2 (best 0.89)
8BVWRNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W)electron microscopyK—1 (best 0.88)
8BZ1RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W)electron microscopyK——
8OEUStructure of the mammalian Pol II-SPT6 complex (composite structure, Structure 4)electron microscopyK—2 (best 0.87)
8OF0Structure of the mammalian Pol II-SPT6-Elongin complex, Structure 1electron microscopyK—1 (best 0.87)
8P4AStructural insights into human co-transcriptional capping - structure 1electron microscopyK—2 (best 0.84)
8P4CStructural insights into human co-transcriptional capping - structure 3electron microscopyK—4 (best 0.84)
8P4DStructural insights into human co-transcriptional capping - structure 4electron microscopyK—4 (best 0.84)
8P4EStructural insights into human co-transcriptional capping - structure 5electron microscopyK—3 (best 0.85)
8P4FStructural insights into human co-transcriptional capping - structure 6electron microscopyK—2 (best 0.88)
8RBXStructure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complexelectron microscopyK—2 (best 0.88)
8W8Ehuman co-transcriptional RNA capping enzyme RNGTTelectron microscopyK—4 (best 0.85)
8WAOStructure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II…electron microscopyy—1 (best 0.86)
8WAQStructure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II…electron microscopyy—1 (best 0.86)
8WAZDe novo transcribing complex 16 (TC16), the early elongation complex with Pol II positioned 16nt…electron microscopyy—2 (best 0.89)
9FD2Structure of Pol II-TC-NER-STK19 complexelectron microscopyK—1 (best 0.89)

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