UniProt P52657
Transcription initiation factor IIA subunit 2 (P52657)
Transcription initiation factor IIA subunit 2 (UniProt P52657): 41 experimental structures on GenesisL1, 5 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P52657
- Protein
- Transcription initiation factor IIA subunit 2
- Experimental structures
- 41
- Predicted models
- 0
- Pockets
- 5 · 1 record with a druggable one
Structures
41 records of P52657 in the MolNFT archive: 41 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1NVP | Human TFIIA/TBP/DNA complex | x-ray diffraction | D | — | — |
| 1NVP | Human TFIIA/TBP/DNA complex | x-ray diffraction | D | — | — |
| 5FUR | Structure of human tfiid-iia bound to core promoter DNA | electron microscopy | D | — | — |
| 5IY6 | Human holo-pic in the closed state | electron microscopy | O | — | — |
| 5IY7 | Human holo-pic in the open state | electron microscopy | O | — | — |
| 5IY8 | Human holo-pic in the initial transcribing state | electron microscopy | O | — | — |
| 5IY9 | Human holo-PIC in the initial transcribing state (no IIS) | electron microscopy | O | — | — |
| 5IY9 | Human holo-pic in the initial transcribing state (no iis) | electron microscopy | O | — | — |
| 5IYA | Human core-PIC in the closed state | electron microscopy | O | — | — |
| 5IYA | Human core-pic in the closed state | electron microscopy | O | — | — |
| 5IYB | Human core-pic in the open state | electron microscopy | O | — | — |
| 5IYC | Human core-pic in the initial transcribing state | electron microscopy | O | — | — |
| 5IYD | Human core-PIC in the initial transcribing state (no IIS) | electron microscopy | O | — | — |
| 5IYD | Human core-pic in the initial transcribing state (no iis) | electron microscopy | O | — | — |
| 5M4S | Transcription factor TFIIA as a single chain protein | x-ray diffraction | A | — | — |
| 5M4S | Transcription factor tfiia as a single chain protein | x-ray diffraction | A | — | — |
| 6MZM | Human tfiid bound to promoter DNA and tfiia | electron microscopy | X | — | — |
| 6O9L | Human holo-pic in the closed state | electron microscopy | O | — | — |
| 7EDX | P53-bound tfiid-based core pic on HDM2 promoter | electron microscopy | O | — | — |
| 7EG7 | Tfiid-based core pic on scp promoter | electron microscopy | O | — | — |
| 7EG8 | Tfiid-based core pic on puma promoter | electron microscopy | O | — | — |
| 7EG9 | Tfiid-based intermediate pic on scp promoter | electron microscopy | O | — | — |
| 7EGA | TFIID-based intermediate PIC on PUMA promoter | electron microscopy | O | — | — |
| 7EGA | Tfiid-based intermediate pic on puma promoter | electron microscopy | O | — | — |
| 7EGC | p53-bound TFIID-based holo PIC on HDM2 promoter | electron microscopy | O | — | — |
| 7EGD | Scp promoter-bound tfiid-tfiia in initial tbp-loading state | electron microscopy | O | — | — |
| 7EGI | Tfiid in rearranged conformation | electron microscopy | O | — | — |
| 7EGJ | Scp promoter-bound tfiid-tfiia in post tbp-loading state | electron microscopy | O | — | — |
| 7ENA | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | electron microscopy | DO | — | — |
| 7ENC | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | electron microscopy | DO | — | — |
| 7NVR | Human Mediator with RNA Polymerase II Pre-initiation complex | electron microscopy | V | — | — |
| 7NVR | Human mediator with RNA polymerase II pre-initiation complex | electron microscopy | V | — | — |
| 7NVS | RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | V | — | — |
| 7NVT | RNA polymerase II core pre-initiation complex with closed promoter DNA in distal position | electron microscopy | V | — | — |
| 7NVU | RNA polymerase II core pre-initiation complex with open promoter DNA | electron microscopy | V | — | — |
| 7NVY | RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | V | — | — |
| 7NVZ | RNA polymerase II pre-initiation complex with closed promoter DNA in distal position | electron microscopy | V | — | — |
| 7NW0 | RNA polymerase II pre-initiation complex with open promoter DNA | electron microscopy | V | — | — |
| 7ZXE | Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC) | electron microscopy | V | — | 5 (best 0.77) |
| 8BZ1 | RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W) | electron microscopy | V | — | — |
| P52657 | AlphaFold monomer V2.0 prediction for transcription initiation factor iia subunit 2 (P52657) | — | — | — |
Elsewhere
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