UniProt Q13888
General transcription factor IIH subunit 2 (Q13888)
General transcription factor IIH subunit 2 (UniProt Q13888): 31 experimental structures on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q13888
- Protein
- General transcription factor IIH subunit 2
- Experimental structures
- 31
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 9 · 3 records with a druggable one
Structures
31 records of Q13888 in the MolNFT archive: 31 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1Z60 | Solution structure of the carboxy-terminal domain of human TFIIH P44 subunit | solution nmr | A | — | — |
| 1Z60 | Solution structure of the carboxy-terminal domain of human tfiih P44 subunit | solution nmr | A | — | — |
| 5IVW | Human core tfiih bound to DNA within the pic | electron microscopy | 0 | — | — |
| 5IY6 | Human holo-PIC in the closed state | electron microscopy | 0 | — | — |
| 5IY6 | Human holo-pic in the closed state | electron microscopy | 0 | — | — |
| 5IY7 | Human holo-pic in the open state | electron microscopy | 0 | — | — |
| 5IY8 | Human holo-pic in the initial transcribing state | electron microscopy | 0 | — | — |
| 5IY9 | Human holo-PIC in the initial transcribing state (no IIS) | electron microscopy | 0 | — | — |
| 5IY9 | Human holo-pic in the initial transcribing state (no iis) | electron microscopy | 0 | — | — |
| 5O85 | p34-p44 complex | x-ray diffraction | B, D | ZN | — |
| 5O85 | P34-P44 complex | x-ray diffraction | B, D | ZN | — |
| 5OF4 | The cryo-EM structure of human TFIIH | electron microscopy | E | — | 4 (best 0.74) |
| 5OF4 | The cryo-EM structure of human tfiih | electron microscopy | E | — | — |
| 6O9L | Human holo-pic in the closed state | electron microscopy | 6 | ZN | — |
| 6O9M | Structure of the human apo tfiih | electron microscopy | 6 | ZN | — |
| 6RO4 | Structure of the core TFIIH-XPA-DNA complex | electron microscopy | D | ZN | — |
| 6RO4 | Structure of the core tfiih-xpa-DNA complex | electron microscopy | D | ZN | — |
| 7AD8 | Core tfiih-xpa-DNA complex with modelled P62 subunit | electron microscopy | D | ZN | — |
| 7EGC | p53-bound TFIID-based holo PIC on HDM2 promoter | electron microscopy | 2 | ZN | — |
| 7ENA | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | electron microscopy | 2 | ZN | — |
| 7ENC | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | electron microscopy | 2 | ZN | — |
| 7NVR | Human Mediator with RNA Polymerase II Pre-initiation complex | electron microscopy | 6 | ZN | — |
| 7NVR | Human mediator with RNA polymerase II pre-initiation complex | electron microscopy | 6 | ZN | — |
| 7NVW | Tfiih in a pre-translocated state (without ADP-BEF3) | electron microscopy | 6 | ZN | — |
| 7NVX | Tfiih in a post-translocated state (with ADP-BEF3) | electron microscopy | 6 | ZN | — |
| 7NVY | RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | 6 | ZN | — |
| 7NVZ | RNA polymerase II pre-initiation complex with closed promoter DNA in distal position | electron microscopy | 6 | ZN | — |
| 7NW0 | RNA polymerase II pre-initiation complex with open promoter DNA | electron microscopy | 6 | ZN | — |
| 8EBU | XPC release from Core7-XPA-DNA (Cy5) | electron microscopy | E | ZN | 2 (best 0.68) |
| 8EBW | Initial DNA-lesion (AP) binding by XPC and TFIIH complex2 | electron microscopy | E | ZN | 3 (best 0.73) |
| Q13888 | AlphaFold monomer V2.0 prediction for general transcription factor iih subunit 2 (Q13888) | — | — | — |
Ligands
- ZN · Zinc ion · in 19 records
Elsewhere
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