UniProt Q6ZYL4
General transcription factor IIH subunit 5 (Q6ZYL4)
General transcription factor IIH subunit 5 (UniProt Q6ZYL4): 63 experimental structures on GenesisL1, 26 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q6ZYL4
- Protein
- General transcription factor IIH subunit 5
- Experimental structures
- 63
- Predicted models
- 0
- Pockets
- 26 · 17 records with a druggable one
Structures
63 records of Q6ZYL4 in the MolNFT archive: 63 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1YDL | Crystal Structure of the Human TFIIH, Northeast Structural Genomics Target HR2045. | x-ray diffraction | A | — | — |
| 1YDL | Crystal structure of the human tfiih, northeast structural genomics target HR2045. | x-ray diffraction | A | — | — |
| 2JNJ | Solution structure of the p8 TFIIH subunit | solution nmr | A, B | — | — |
| 2JNJ | Solution structure of the P8 tfiih subunit | solution nmr | A, B | — | — |
| 5IVW | Human core TFIIH bound to DNA within the PIC | electron microscopy | 1 | — | 1 (best 0.63) |
| 5IVW | Human core tfiih bound to DNA within the pic | electron microscopy | 1 | — | — |
| 5IY6 | Human holo-PIC in the closed state | electron microscopy | 1 | — | — |
| 5IY6 | Human holo-pic in the closed state | electron microscopy | 1 | — | — |
| 5IY7 | Human holo-PIC in the open state | electron microscopy | 1 | — | — |
| 5IY7 | Human holo-pic in the open state | electron microscopy | 1 | — | — |
| 5IY8 | Human holo-PIC in the initial transcribing state | electron microscopy | 1 | — | — |
| 5IY8 | Human holo-pic in the initial transcribing state | electron microscopy | 1 | — | — |
| 5IY9 | Human holo-PIC in the initial transcribing state (no IIS) | electron microscopy | 1 | — | — |
| 5IY9 | Human holo-pic in the initial transcribing state (no iis) | electron microscopy | 1 | — | — |
| 5OF4 | The cryo-EM structure of human TFIIH | electron microscopy | G | — | 2 (best 0.76) |
| 5OF4 | The cryo-EM structure of human tfiih | electron microscopy | G | — | — |
| 6NMI | Cryo-EM structure of the human TFIIH core complex | electron microscopy | G | — | — |
| 6NMI | Cryo-EM structure of the human tfiih core complex | electron microscopy | G | — | — |
| 6O9L | Human holo-PIC in the closed state | electron microscopy | 5 | — | 1 (best 0.83) |
| 6O9L | Human holo-pic in the closed state | electron microscopy | 5 | — | — |
| 6O9M | Structure of the human apo TFIIH | electron microscopy | 5 | — | 1 (best 0.86) |
| 6O9M | Structure of the human apo tfiih | electron microscopy | 5 | — | — |
| 6RO4 | Structure of the core TFIIH-XPA-DNA complex | electron microscopy | F | — | — |
| 6RO4 | Structure of the core tfiih-xpa-DNA complex | electron microscopy | F | — | — |
| 7AD8 | Core TFIIH-XPA-DNA complex with modelled p62 subunit | electron microscopy | F | — | 1 (best 0.69) |
| 7AD8 | Core tfiih-xpa-DNA complex with modelled P62 subunit | electron microscopy | F | — | — |
| 7EGB | TFIID-based holo PIC on SCP promoter | electron microscopy | 5 | — | — |
| 7EGC | p53-bound TFIID-based holo PIC on HDM2 promoter | electron microscopy | 5 | — | — |
| 7ENA | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | electron microscopy | 5 | — | — |
| 7ENC | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | electron microscopy | 5 | — | — |
| 7LBM | Structure of the human Mediator-bound transcription pre-initiation complex | electron microscopy | c | — | 1 (best 0.79) |
| 7NVR | Human Mediator with RNA Polymerase II Pre-initiation complex | electron microscopy | 5 | — | — |
| 7NVR | Human mediator with RNA polymerase II pre-initiation complex | electron microscopy | 5 | — | — |
| 7NVV | XPB-containing part of TFIIH in a post-translocated state (with ADP-BeF3) | electron microscopy | 5 | — | — |
| 7NVV | Xpb-containing part of tfiih in a post-translocated state (with ADP- BEF3) | electron microscopy | 5 | — | — |
| 7NVW | Tfiih in a pre-translocated state (without ADP-BEF3) | electron microscopy | 5 | — | — |
| 7NVX | TFIIH in a post-translocated state (with ADP-BeF3) | electron microscopy | 5 | — | 1 (best 0.79) |
| 7NVX | Tfiih in a post-translocated state (with ADP-BEF3) | electron microscopy | 5 | — | — |
| 7NVY | RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | 5 | — | 1 (best 0.75) |
| 7NVY | RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position | electron microscopy | 5 | — | — |
| 7NVZ | RNA polymerase II pre-initiation complex with closed promoter DNA in distal position | electron microscopy | 5 | — | — |
| 7NW0 | RNA polymerase II pre-initiation complex with open promoter DNA | electron microscopy | 5 | — | 1 (best 0.79) |
| 7NW0 | RNA polymerase II pre-initiation complex with open promoter DNA | electron microscopy | 5 | — | — |
| 8BVW | RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W) | electron microscopy | 6 | — | 1 (best 0.78) |
| 8BYQ | RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W) | electron microscopy | 6 | — | — |
| 8EBS | Initial DNA-lesion (Cy5) binding by XPC and TFIIH | electron microscopy | G | — | 2 (best 0.79) |
| 8EBT | XPA repositioning Core7 of TFIIH relative to XPC-DNA lesion (Cy5) | electron microscopy | G | — | 3 (best 0.79) |
| 8EBU | XPC release from Core7-XPA-DNA (Cy5) | electron microscopy | G | — | 3 (best 0.83) |
| 8EBV | Initial DNA-lesion (AP) binding by XPC and TFIIH complex 1 | electron microscopy | G | — | 1 (best 0.76) |
| 8EBW | Initial DNA-lesion (AP) binding by XPC and TFIIH complex2 | electron microscopy | G | — | 2 (best 0.78) |
| 8EBX | XPA repositioning Core7 of TFIIH relative to XPC-DNA lesion (AP) | electron microscopy | G | — | 2 (best 0.84) |
| 8EBY | XPC release from Core7-XPA-DNA (AP) | electron microscopy | G | — | 2 (best 0.83) |
| 8GXQ | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | electron microscopy | HF | — | — |
| 8GXS | PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state | electron microscopy | HF | — | — |
| 8WAK | Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II… | electron microscopy | 5 | — | — |
| 8WAL | Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II… | electron microscopy | 5 | — | — |
| 8WAN | Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II… | electron microscopy | 5 | — | — |
| 8WAO | Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II… | electron microscopy | 5 | — | — |
| 8WAP | Structure of transcribing complex 6 (TC6), the initially transcribing complex with Pol II… | electron microscopy | 5 | — | — |
| 8WAQ | Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II… | electron microscopy | 5 | — | — |
3 records more on the page itself.
Elsewhere
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