MolNFT v1 · #158186 · protein
Cryo-EM structure of the human tfiih core complex
6NMI: “Cryo-EM structure of the human tfiih core complex”. Electron microscopy, 2 ligands (SF4, ZN). MolNFT v1 #158186 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6NMI
- Type
- protein
- Length
- 3,178 residues
- Chains
- 8
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q92759, Q13889, Q6ZYL4, P51948
- Ligands
- SF4, ZN
Structure
electron microscopy · 8 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 653 | — | — |
| B | — | protein | 760 | — | — |
| C | — | protein | 408 | — | — |
| D | — | protein | 452 | — | Q92759 |
| E | — | protein | 366 | — | — |
| F | — | protein | 263 | — | Q13889 |
| G | — | protein | 66 | — | Q6ZYL4 |
| H | — | protein | 210 | — | P51948 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6NMI · Cryo-EM structure of the human TFIIH core complex · the same entry in another collection · chain H against H, TM-score 1.00
- Q13889 · AlphaFold monomer V2.0 prediction for general transcription factor iih subunit 3 (Q13889) · a predicted model of the same protein · chain F against A, TM-score 0.92
- P51948 · AlphaFold monomer V2.0 prediction for cdk-activating kinase assembly factor MAT1 (P51948) · a predicted model of the same protein · chain H against A, TM-score 0.75
- Q6ZYL4 · AlphaFold monomer V2.0 prediction for general transcription factor iih subunit 5 (Q6ZYL4) · a predicted model of the same protein · chain G against A, TM-score 0.75
- Q92759 · AlphaFold monomer V2.0 prediction for general transcription factor iih subunit 4 (Q92759) · a predicted model of the same protein · chain D against A, TM-score 0.74
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q92759
- Every structure of UniProt Q13889
- Every structure of UniProt Q6ZYL4
- Every structure of UniProt P51948
- Elsewhere: RCSB PDB 6NMI · PDBe 6NMI · UniProt Q92759 · UniProt Q13889 · UniProt Q6ZYL4 · UniProt P51948
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