MolNFT v1 · #129265 · protein
The cryo-EM structure of human tfiih
5OF4: “The cryo-EM structure of human tfiih”. Electron microscopy, 1 ligand (SF4). MolNFT v1 #129265 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5OF4
- Type
- protein
- Length
- 2,463 residues
- Chains
- 10
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P19447, P18074, Q92759, Q13888, Q13889, Q6ZYL4
- Ligands
- SF4
Structure
electron microscopy · 10 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 499 | — | P19447 |
| B | — | protein | 724 | — | P18074 |
| D | — | protein | 81 | — | Q92759 |
| E | — | protein | 184 | — | Q13888 |
| F | — | protein | 205 | — | Q13889 |
| G | — | protein | 66 | — | Q6ZYL4 |
| H | — | protein | 124 | — | — |
| Z | — | protein | 270 | — | — |
| Y | — | protein | 232 | — | — |
| X | — | protein | 78 | — | — |
Ligands and binding sites
- SF4 · Iron/sulfur cluster · ligand · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5OF4 · The cryo-EM structure of human TFIIH · the same entry in another collection · chain X against X, TM-score 1.00
- Q13888 · AlphaFold monomer V2.0 prediction for general transcription factor iih subunit 2 (Q13888) · a predicted model of the same protein · chain E against A, TM-score 0.98
- P18074 · AlphaFold monomer V2.0 prediction for general transcription and DNA repair factor iih… · a predicted model of the same protein · chain B against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19447
- Every structure of UniProt P18074
- Every structure of UniProt Q92759
- Every structure of UniProt Q13888
- Every structure of UniProt Q13889
- Every structure of UniProt Q6ZYL4
- Elsewhere: RCSB PDB 5OF4 · PDBe 5OF4 · UniProt P19447 · UniProt P18074 · UniProt Q92759 · UniProt Q13888 · UniProt Q13889 · UniProt Q6ZYL4
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