MolNFT v1 · #126498 · protein
Transcription factor tfiia as a single chain protein
5M4S · Transcription initiation factor iia subunit 2,TRANSCRIPTION…: “Transcription factor tfiia as a single chain protein”. X-ray diffraction, 1 pocket (best druggability 0.58). MolNFT v1 #126498 on GenesisL1: 3D structure, binding sites…
- PDB
- 5M4S
- Type
- protein
- Length
- 209 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcription initiation factor iia subunit 2,TRANSCRIPTION initiation factor iia subunit…
- UniProt
- P52657, P52655
- Pockets
- 1 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcription initiation factor iia subunit 2,TRANSCRIPTION initiation factor iia subunit 1,TRANSCRIPTION initiation factor iia subunit 1 | protein | 209 | 37% helix, 37% strand | P52657, P52655 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 388 | 0.58 | 0.75 | 49 | empty |
Compared structures
- 5M4S · Transcription factor TFIIA as a single chain protein · the same entry in another collection · chain A against A, TM-score 1.00
- P52657 · AlphaFold monomer V2.0 prediction for transcription initiation factor iia subunit 2… · a predicted model of the same protein · chain A against A, TM-score 0.49
- P52655 · AlphaFold monomer V2.0 prediction for transcription initiation factor iia subunit 1… · a predicted model of the same protein · chain A against A, TM-score 0.43
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P52657
- Every structure of UniProt P52655
- Elsewhere: RCSB PDB 5M4S · PDBe 5M4S · UniProt P52657 · UniProt P52655
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