UniProt Q15544
Transcription initiation factor TFIID subunit 11 (Q15544)
Transcription initiation factor TFIID subunit 11 (UniProt Q15544): 40 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 80 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q15544
- Protein
- Transcription initiation factor TFIID subunit 11
- Experimental structures
- 40
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 80 · 34 records with a druggable one
Structures
41 records of Q15544 in the MolNFT archive: 40 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BH8 | HTAFII18/HTAFII28 heterodimer crystal structure | x-ray diffraction | B | — | — |
| 1BH8 | HTAFII18/HTAFII28 heterodimer crystal structure | x-ray diffraction | B | — | — |
| 1BH9 | HTAFII18/HTAFII28 heterodimer crystal structure with bound pcmbs | x-ray diffraction | B | PMB | — |
| 1BH9 | HTAFII18/HTAFII28 heterodimer crystal structure with bound pcmbs | x-ray diffraction | B | PMB | — |
| 6MZD | Human TFIID Lobe A canonical | electron microscopy | P | — | 1 (best 0.68) |
| 6MZD | Human tfiid lobe a canonical | electron microscopy | P | — | 1 (best 0.68) |
| 6MZL | Human TFIID canonical state | electron microscopy | P | — | — |
| 6MZL | Human tfiid canonical state | electron microscopy | P | — | — |
| 7EDX | p53-bound TFIID-based core PIC on HDM2 promoter | electron microscopy | k | — | 2 (best 0.85) |
| 7EDX | P53-bound tfiid-based core pic on HDM2 promoter | electron microscopy | k | — | 2 (best 0.85) |
| 7EG7 | TFIID-based core PIC on SCP promoter | electron microscopy | k | — | 2 (best 0.87) |
| 7EG7 | Tfiid-based core pic on scp promoter | electron microscopy | k | — | 2 (best 0.87) |
| 7EG8 | TFIID-based core PIC on PUMA promoter | electron microscopy | k | — | 2 (best 0.87) |
| 7EG8 | Tfiid-based core pic on puma promoter | electron microscopy | k | — | 2 (best 0.87) |
| 7EG9 | TFIID-based intermediate PIC on SCP promoter | electron microscopy | k | — | 2 (best 0.86) |
| 7EG9 | Tfiid-based intermediate pic on scp promoter | electron microscopy | k | — | 2 (best 0.86) |
| 7EGA | TFIID-based intermediate PIC on PUMA promoter | electron microscopy | k | — | 2 (best 0.86) |
| 7EGA | Tfiid-based intermediate pic on puma promoter | electron microscopy | k | — | 2 (best 0.86) |
| 7EGB | TFIID-based holo PIC on SCP promoter | electron microscopy | k | — | 2 (best 0.86) |
| 7EGC | p53-bound TFIID-based holo PIC on HDM2 promoter | electron microscopy | k | — | 2 (best 0.87) |
| 7EGD | Scp promoter-bound tfiid-tfiia in initial tbp-loading state | electron microscopy | k | — | 5 (best 0.87) |
| 7EGE | TFIID in canonical conformation | electron microscopy | k | — | 3 (best 0.86) |
| 7EGE | Tfiid in canonical conformation | electron microscopy | k | — | 3 (best 0.86) |
| 7EGF | TFIID lobe A subcomplex | electron microscopy | k | — | 6 (best 0.86) |
| 7EGF | Tfiid lobe a subcomplex | electron microscopy | k | — | 6 (best 0.86) |
| 7EGI | TFIID in rearranged conformation | electron microscopy | k | — | 2 (best 0.86) |
| 7EGI | Tfiid in rearranged conformation | electron microscopy | k | — | 2 (best 0.86) |
| 7EGJ | Scp promoter-bound tfiid-tfiia in post tbp-loading state | electron microscopy | k | — | 3 (best 0.87) |
| 7ENA | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | electron microscopy | Dk | — | 1 (best 0.86) |
| 7ENC | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | electron microscopy | Dk | — | 2 (best 0.88) |
| 8GXQ | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | electron microscopy | Dk | — | 2 (best 0.86) |
| 8GXS | PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state | electron microscopy | Dk | — | 2 (best 0.88) |
| 8WAK | Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II… | electron microscopy | k | — | 3 (best 0.86) |
| 8WAL | Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II… | electron microscopy | k | — | 2 (best 0.86) |
| 8WAN | Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II… | electron microscopy | k | — | 2 (best 0.86) |
| 8WAO | Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II… | electron microscopy | k | — | 2 (best 0.87) |
| 8WAP | Structure of transcribing complex 6 (TC6), the initially transcribing complex with Pol II… | electron microscopy | k | — | 2 (best 0.86) |
| 8WAQ | Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II… | electron microscopy | k | — | 2 (best 0.86) |
| 8WAR | Structure of transcribing complex 8 (TC8), the initially transcribing complex with Pol II… | electron microscopy | k | — | 2 (best 0.86) |
| 8WAS | Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II… | electron microscopy | k | — | 2 (best 0.86) |
| Q15544 | AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 11 (Q15544) | predicted | A | — | — |
Ligands
- PMB · Para-mercury-benzenesulfonic acid · in 2 records
Experiment against prediction
- 1BH8 chain B against the predicted model Q15544: TM-score 0.95, RMSD 0.81 Å
- 1BH8 chain B against the predicted model Q15544: TM-score 0.95, RMSD 0.81 Å
- 1BH9 chain B against the predicted model Q15544: TM-score 0.95, RMSD 0.83 Å
- 1BH9 chain B against the predicted model Q15544: TM-score 0.95, RMSD 0.83 Å
- 6MZD chain P against the predicted model Q15544: TM-score 0.92, RMSD 1.05 Å
- 6MZL chain P against the predicted model Q15544: TM-score 0.92, RMSD 1.05 Å
- 6MZD chain P against the predicted model Q15544: TM-score 0.92, RMSD 1.05 Å
- 6MZL chain P against the predicted model Q15544: TM-score 0.92, RMSD 1.05 Å
- 7ENC chain Dk against the predicted model Q15544: TM-score 0.90, RMSD 1.56 Å
- 7ENA chain Dk against the predicted model Q15544: TM-score 0.90, RMSD 1.77 Å
Elsewhere
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