UniProt Q15545
Transcription initiation factor TFIID subunit 7 (Q15545)
Transcription initiation factor TFIID subunit 7 (UniProt Q15545): 40 experimental structures and 1 predicted model on GenesisL1, 44 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15545
- Protein
- Transcription initiation factor TFIID subunit 7
- Experimental structures
- 40
- Predicted models
- 1
- Pockets
- 44 · 16 records with a druggable one
Structures
41 records of Q15545 in the MolNFT archive: 40 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4RGW | Crystal Structure of a TAF1-TAF7 Complex in Human Transcription Factor IID | x-ray diffraction | B | — | 6 (best 0.69) |
| 4RGW | Crystal structure of a TAF1-TAF7 complex in human transcription factor iid | x-ray diffraction | B | — | 6 (best 0.69) |
| 5FUR | Structure of human TFIID-IIA bound to core promoter DNA | electron microscopy | H | — | 4 (best 0.72) |
| 5FUR | Structure of human tfiid-iia bound to core promoter DNA | electron microscopy | H | — | 4 (best 0.72) |
| 6MZL | Human TFIID canonical state | electron microscopy | J | — | 2 (best 0.76) |
| 6MZL | Human tfiid canonical state | electron microscopy | J | — | 2 (best 0.76) |
| 6MZM | Human TFIID bound to promoter DNA and TFIIA | electron microscopy | J | — | 1 (best 0.70) |
| 6MZM | Human tfiid bound to promoter DNA and tfiia | electron microscopy | J | — | 1 (best 0.70) |
| 7EDX | p53-bound TFIID-based core PIC on HDM2 promoter | electron microscopy | G | — | — |
| 7EDX | P53-bound tfiid-based core pic on HDM2 promoter | electron microscopy | G | — | — |
| 7EG7 | TFIID-based core PIC on SCP promoter | electron microscopy | G | — | — |
| 7EG7 | Tfiid-based core pic on scp promoter | electron microscopy | G | — | — |
| 7EG8 | TFIID-based core PIC on PUMA promoter | electron microscopy | G | — | — |
| 7EG8 | Tfiid-based core pic on puma promoter | electron microscopy | G | — | — |
| 7EG9 | TFIID-based intermediate PIC on SCP promoter | electron microscopy | G | — | — |
| 7EG9 | Tfiid-based intermediate pic on scp promoter | electron microscopy | G | — | — |
| 7EGA | TFIID-based intermediate PIC on PUMA promoter | electron microscopy | G | — | — |
| 7EGA | Tfiid-based intermediate pic on puma promoter | electron microscopy | G | — | — |
| 7EGB | TFIID-based holo PIC on SCP promoter | electron microscopy | G | — | — |
| 7EGC | p53-bound TFIID-based holo PIC on HDM2 promoter | electron microscopy | G | — | — |
| 7EGD | Scp promoter-bound tfiid-tfiia in initial tbp-loading state | electron microscopy | G | — | 2 (best 0.70) |
| 7EGE | TFIID in canonical conformation | electron microscopy | G | — | 2 (best 0.71) |
| 7EGE | Tfiid in canonical conformation | electron microscopy | G | — | 2 (best 0.71) |
| 7EGH | TFIID lobe C subcomplex | electron microscopy | G | — | 3 (best 0.69) |
| 7EGH | Tfiid lobe C subcomplex | electron microscopy | G | — | 3 (best 0.69) |
| 7EGI | TFIID in rearranged conformation | electron microscopy | G | — | 2 (best 0.72) |
| 7EGI | Tfiid in rearranged conformation | electron microscopy | G | — | 2 (best 0.72) |
| 7EGJ | Scp promoter-bound tfiid-tfiia in post tbp-loading state | electron microscopy | G | — | 2 (best 0.71) |
| 7ENA | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | electron microscopy | DG | — | — |
| 7ENC | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | electron microscopy | DG | — | — |
| 8GXQ | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | electron microscopy | DG | — | — |
| 8GXS | PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state | electron microscopy | DG | — | — |
| 8WAK | Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II… | electron microscopy | G | — | — |
| 8WAL | Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II… | electron microscopy | G | — | — |
| 8WAN | Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II… | electron microscopy | G | — | — |
| 8WAO | Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II… | electron microscopy | G | — | — |
| 8WAP | Structure of transcribing complex 6 (TC6), the initially transcribing complex with Pol II… | electron microscopy | G | — | — |
| 8WAQ | Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II… | electron microscopy | G | — | — |
| 8WAR | Structure of transcribing complex 8 (TC8), the initially transcribing complex with Pol II… | electron microscopy | G | — | — |
| 8WAS | Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II… | electron microscopy | G | — | — |
| Q15545 | AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 7 (Q15545) | predicted | A | — | — |
Experiment against prediction
- 6MZL chain J against the predicted model Q15545: TM-score 0.96, RMSD 0.87 Å
- 6MZL chain J against the predicted model Q15545: TM-score 0.96, RMSD 0.87 Å
- 6MZM chain J against the predicted model Q15545: TM-score 0.96, RMSD 0.87 Å
- 6MZM chain J against the predicted model Q15545: TM-score 0.96, RMSD 0.87 Å
- 4RGW chain B against the predicted model Q15545: TM-score 0.96, RMSD 0.87 Å
- 4RGW chain B against the predicted model Q15545: TM-score 0.96, RMSD 0.87 Å
- 5FUR chain H against the predicted model Q15545: TM-score 0.96, RMSD 0.87 Å
- 5FUR chain H against the predicted model Q15545: TM-score 0.96, RMSD 0.87 Å
- 7EGE chain G against the predicted model Q15545: TM-score 0.78, RMSD 1.30 Å
- 7EGE chain G against the predicted model Q15545: TM-score 0.78, RMSD 1.30 Å
Elsewhere
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