UniProt Q15543
Transcription initiation factor TFIID subunit 13 (Q15543)
Transcription initiation factor TFIID subunit 13 (UniProt Q15543): 28 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15543
- Protein
- Transcription initiation factor TFIID subunit 13
- Experimental structures
- 28
- Predicted models
- 1
- Pockets
- 5 · 5 records with a druggable one
Structures
29 records of Q15543 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BH8 | HTAFII18/HTAFII28 heterodimer crystal structure | x-ray diffraction | A | — | — |
| 1BH8 | HTAFII18/HTAFII28 heterodimer crystal structure | x-ray diffraction | A | — | — |
| 1BH9 | HTAFII18/HTAFII28 heterodimer crystal structure with bound pcmbs | x-ray diffraction | A | — | — |
| 1BH9 | HTAFII18/HTAFII28 heterodimer crystal structure with bound pcmbs | x-ray diffraction | A | — | — |
| 6MZD | Human tfiid lobe a canonical | electron microscopy | S | — | — |
| 6MZL | Human TFIID canonical state | electron microscopy | S | — | — |
| 6MZL | Human tfiid canonical state | electron microscopy | S | — | — |
| 7EDX | p53-bound TFIID-based core PIC on HDM2 promoter | electron microscopy | m | — | 1 (best 0.81) |
| 7EDX | P53-bound tfiid-based core pic on HDM2 promoter | electron microscopy | m | — | — |
| 7EG7 | Tfiid-based core pic on scp promoter | electron microscopy | m | — | — |
| 7EG8 | Tfiid-based core pic on puma promoter | electron microscopy | m | — | — |
| 7EG9 | Tfiid-based intermediate pic on scp promoter | electron microscopy | m | — | — |
| 7EGA | TFIID-based intermediate PIC on PUMA promoter | electron microscopy | m | — | — |
| 7EGA | Tfiid-based intermediate pic on puma promoter | electron microscopy | m | — | — |
| 7EGB | TFIID-based holo PIC on SCP promoter | electron microscopy | m | — | 1 (best 0.82) |
| 7EGC | p53-bound TFIID-based holo PIC on HDM2 promoter | electron microscopy | m | — | — |
| 7EGD | Scp promoter-bound tfiid-tfiia in initial tbp-loading state | electron microscopy | m | — | — |
| 7EGE | Tfiid in canonical conformation | electron microscopy | m | — | — |
| 7EGF | TFIID lobe A subcomplex | electron microscopy | m | — | — |
| 7EGF | Tfiid lobe a subcomplex | electron microscopy | m | — | — |
| 7EGI | TFIID in rearranged conformation | electron microscopy | m | — | 1 (best 0.84) |
| 7EGI | Tfiid in rearranged conformation | electron microscopy | m | — | — |
| 7EGJ | Scp promoter-bound tfiid-tfiia in post tbp-loading state | electron microscopy | m | — | — |
| 7ENA | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | electron microscopy | Dm | — | — |
| 7ENC | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | electron microscopy | Dm | — | — |
| 8GXQ | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | electron microscopy | Dm | — | 1 (best 0.83) |
| 8WAO | Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II… | electron microscopy | m | — | 1 (best 0.85) |
| 8WAQ | Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II… | electron microscopy | m | — | — |
| Q15543 | AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 13 (Q15543) | predicted | A | — | — |
Experiment against prediction
- 1BH9 chain A against the predicted model Q15543: TM-score 0.93, RMSD 0.61 Å
- 1BH9 chain A against the predicted model Q15543: TM-score 0.93, RMSD 0.61 Å
- 6MZL chain S against the predicted model Q15543: TM-score 0.93, RMSD 0.58 Å
- 6MZD chain S against the predicted model Q15543: TM-score 0.93, RMSD 0.58 Å
- 6MZL chain S against the predicted model Q15543: TM-score 0.93, RMSD 0.58 Å
- 1BH8 chain A against the predicted model Q15543: TM-score 0.93, RMSD 0.59 Å
- 1BH8 chain A against the predicted model Q15543: TM-score 0.93, RMSD 0.59 Å
- 7EGD chain m against the predicted model Q15543: TM-score 0.92, RMSD 0.98 Å
- 7EGJ chain m against the predicted model Q15543: TM-score 0.91, RMSD 1.16 Å
- 7EGI chain m against the predicted model Q15543: TM-score 0.91, RMSD 1.16 Å
Elsewhere
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