MolNFT v2 · #150215 · protein
26S proteasome, s1 state
6FVT: “26S proteasome, s1 state”. Electron microscopy at 4.1, 3 ligands (ATP, ADP, MG). MolNFT v2 #150215 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6FVT
- Type
- protein
- Length
- 14,028 residues
- Chains
- 47
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 4.1
- Source
- Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
- UniProt
- P21243, P23639, P23638, P40303, P32379, P40302, P21242, P38624, P25043, P25451, P22141, P30656, P23724, P30657, P38886, P43588, P32496, O13563, O94742, P38764, P32565, P40016, Q12250, Q12377, Q06103, Q08723, Q04062, P33299, P40327, P33298, P53549, P33297, Q01939
- Ligands
- ATP, ADP, MG
Structure
electron microscopy · resolution 4.1 · 35 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| a, A | — | protein | 241 | — | P21243 |
| b, B | — | protein | 249 | — | P23639 |
| c, C | — | protein | 244 | — | P23638 |
| d | — | protein | 251 | — | P40303 |
| e, E | — | protein | 244 | — | P32379 |
| f, F | — | protein | 231 | — | P40302 |
| g, G | — | protein | 245 | — | P21242 |
| h, 1 | — | protein | 196 | — | P38624 |
| i, 2 | — | protein | 226 | — | P25043 |
| j, 3 | — | protein | 204 | — | P25451 |
| k, 4 | — | protein | 195 | — | P22141 |
| l, 5 | — | protein | 212 | — | P30656 |
| m, 6 | — | protein | 222 | — | P23724 |
| n | — | protein | 232 | — | P30657 |
| D | — | protein | 237 | — | P40303 |
| 7 | — | protein | 229 | — | P30657 |
| W | — | protein | 197 | — | P38886 |
| V | — | protein | 289 | — | P43588 |
| T | — | protein | 266 | — | P32496 |
| X | — | protein | 127 | — | O13563 |
| Y | — | protein | 89 | — | O94742 |
| Z | — | protein | 906 | — | P38764 |
| N | — | protein | 922 | — | P32565 |
| S | — | protein | 475 | — | P40016 |
| P | — | protein | 440 | — | Q12250 |
| Q | — | protein | 434 | — | Q12377 |
| R | — | protein | 405 | — | Q06103 |
| U | — | protein | 304 | — | Q08723 |
| O | — | protein | 388 | — | Q04062 |
| H | — | protein | 426 | — | P33299 |
| I | — | protein | 385 | — | P40327 |
| K | — | protein | 394 | — | P33298 |
| L | — | protein | 388 | — | P53549 |
| M | — | protein | 421 | — | P33297 |
| J | — | protein | 405 | — | Q01939 |
Ligands and binding sites
- ATP · Adenosine-5'-triphosphate · ligand · 5 copies · chains H, I, J, K, L, M
- ADP · Adenosine-5'-diphosphate · ligand · chains J
- MG · Magnesium ion · metal · 6 copies · chains H, M, I, J, K, L
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- P53549 · AlphaFold monomer V2.0 prediction for 26S proteasome subunit RPT4 (P53549) · a predicted model of the same protein · chain L against A, TM-score 0.95
- P33298 · AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit 6B homolog… · a predicted model of the same protein · chain K against A, TM-score 0.93
- Q06103 · AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN7 (Q06103) · a predicted model of the same protein · chain R against A, TM-score 0.93
- P38886 · AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN10 (P38886) · a predicted model of the same protein · chain W against A, TM-score 0.93
- Q08723 · AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN8 (Q08723) · a predicted model of the same protein · chain U against A, TM-score 0.92
- P40016 · AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN3 (P40016) · a predicted model of the same protein · chain S against A, TM-score 0.92
- P33299 · AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit 7 homolog (P33299) · a predicted model of the same protein · chain H against A, TM-score 0.91
- Q12250 · AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN5 (Q12250) · a predicted model of the same protein · chain P against A, TM-score 0.90
- P43588 · AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase RPN11 (P43588) · a predicted model of the same protein · chain V against A, TM-score 0.90
- P33297 · AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit 6A (P33297) · a predicted model of the same protein · chain M against A, TM-score 0.90
- Q04062 · AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN9 (Q04062) · a predicted model of the same protein · chain O against A, TM-score 0.89
- P40327 · AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit 4 homolog (P40327) · a predicted model of the same protein · chain I against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21243
- Every structure of UniProt P23639
- Every structure of UniProt P23638
- Every structure of UniProt P40303
- Every structure of UniProt P32379
- Every structure of UniProt P40302
- Every structure of UniProt P21242
- Every structure of UniProt P38624
- Every structure of UniProt P25043
- Every structure of UniProt P25451
- Every structure of UniProt P22141
- Every structure of UniProt P30656
- Every structure of UniProt P23724
- Every structure of UniProt P30657
- Every structure of UniProt P38886
- Every structure of UniProt P43588
- Every structure of UniProt P32496
- Every structure of UniProt O13563
- Every structure of UniProt O94742
- Every structure of UniProt P38764
- Every structure of UniProt P32565
- Every structure of UniProt P40016
- Every structure of UniProt Q12250
- Every structure of UniProt Q12377
- Every structure of UniProt Q06103
- Every structure of UniProt Q08723
- Every structure of UniProt Q04062
- Every structure of UniProt P33299
- Every structure of UniProt P40327
- Every structure of UniProt P33298
- Every structure of UniProt P53549
- Every structure of UniProt P33297
- Every structure of UniProt Q01939
- Elsewhere: RCSB PDB 6FVT · PDBe 6FVT · UniProt P21243 · UniProt P23639 · UniProt P23638 · UniProt P40303 · UniProt P32379 · UniProt P40302 · UniProt P21242 · UniProt P38624 · UniProt P25043 · UniProt P25451 · UniProt P22141 · UniProt P30656 · UniProt P23724 · UniProt P30657 · UniProt P38886 · UniProt P43588 · UniProt P32496 · UniProt O13563 · UniProt O94742 · UniProt P38764 · UniProt P32565 · UniProt P40016 · UniProt Q12250 · UniProt Q12377 · UniProt Q06103 · UniProt Q08723 · UniProt Q04062 · UniProt P33299 · UniProt P40327 · UniProt P33298 · UniProt P53549 · UniProt P33297 · UniProt Q01939
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