UniProt P32496
26S proteasome regulatory subunit RPN12 (P32496)
26S proteasome regulatory subunit RPN12 (UniProt P32496): 37 experimental structures on GenesisL1, 28 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P32496
- Protein
- 26S proteasome regulatory subunit RPN12
- Experimental structures
- 37
- Predicted models
- 0
- Pockets
- 28 · 14 records with a druggable one
Structures
37 records of P32496 in the MolNFT archive: 37 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3J47 | Formation of an intricate helical bundle dictates the assembly of the 26S proteasome lid | electron microscopy | T | — | — |
| 3J47 | Formation of an intricate helical bundle dictates the assembly of the 26S proteasome lid | electron microscopy | T | — | — |
| 3JCK | Structure of the yeast 26S proteasome lid sub-complex | electron microscopy | H | — | — |
| 3JCK | Structure of the yeast 26S proteasome lid sub-complex | electron microscopy | H | — | — |
| 3JCO | Structure of yeast 26S proteasome in M1 state derived from Titan dataset | electron microscopy | T | — | — |
| 3JCP | Structure of yeast 26S proteasome in M2 state derived from Titan dataset | electron microscopy | T | — | — |
| 4CR2 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | T | — | — |
| 4CR2 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | T | — | — |
| 4CR3 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | T | — | — |
| 4CR3 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | T | — | — |
| 4CR4 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | T | — | — |
| 4CR4 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | T | — | — |
| 5A5B | Structure of the 26S proteasome-Ubp6 complex | electron microscopy | T | — | — |
| 5A5B | Structure of the 26S proteasome-UBP6 complex | electron microscopy | T | — | — |
| 5MPB | 26S proteasome in presence of AMP-PNP (s3) | electron microscopy | T | — | 2 (best 0.83) |
| 5MPC | 26S proteasome in presence of BeFx (s4) | electron microscopy | T | — | — |
| 5MPD | 26S proteasome in presence of ATP (s1) | electron microscopy | T | — | 5 (best 0.81) |
| 5MPD | 26S proteasome in presence of ATP (S1) | electron microscopy | T | — | — |
| 5MPE | 26S proteasome in presence of ATP (s2) | electron microscopy | T | — | — |
| 5MPE | 26S proteasome in presence of ATP (S2) | electron microscopy | T | — | — |
| 5WVI | The resting state of yeast proteasome | electron microscopy | T | — | — |
| 5WVK | Yeast proteasome-ADP-AlFx | electron microscopy | T | — | 3 (best 0.83) |
| 6FVT | 26S proteasome, s1 state | electron microscopy | T | — | — |
| 6FVU | 26S proteasome, s2 state | electron microscopy | T | — | 1 (best 0.78) |
| 6FVV | 26S proteasome, s3 state | electron microscopy | T | — | 1 (best 0.82) |
| 6FVW | 26S proteasome, s4 state | electron microscopy | T | — | 1 (best 0.78) |
| 6FVX | 26S proteasome, s5 state | electron microscopy | T | — | 1 (best 0.78) |
| 6FVY | 26S proteasome, s6 state | electron microscopy | T | — | 2 (best 0.77) |
| 6J2C | Yeast proteasome in translocation competent state (C3-a) | electron microscopy | T | — | 1 (best 0.81) |
| 6J2N | yeast proteasome in substrate-processing state (C3-b) | electron microscopy | T | — | 3 (best 0.86) |
| 6J2Q | Yeast proteasome in Ub-accepted state (C1-b) | electron microscopy | T | — | 2 (best 0.87) |
| 6J2X | Yeast proteasome in resting state (C1-a) | electron microscopy | T | — | — |
| 6J30 | yeast proteasome in Ub-engaged state (C2) | electron microscopy | T | — | 2 (best 0.82) |
| 7QO3 | Structure of the 26S proteasome-Ubp6 complex in the si state (Core Particle and Lid) | electron microscopy | T | — | 2 (best 0.75) |
| 7QO3 | Structure of the 26S proteasome-UBP6 complex in the si state (core particle and lid) | electron microscopy | T | — | — |
| 7QO5 | 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state | electron microscopy | T | — | 2 (best 0.80) |
| P32496 | AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN12 (P32496) | — | — | — |
Elsewhere
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