UniProt Q04062
26S proteasome regulatory subunit RPN9 (Q04062)
26S proteasome regulatory subunit RPN9 (UniProt Q04062): 38 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q04062
- Protein
- 26S proteasome regulatory subunit RPN9
- Experimental structures
- 38
- Predicted models
- 1
- Pockets
- 13 · 7 records with a druggable one
Structures
39 records of Q04062 in the MolNFT archive: 38 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2MQW | Solution structure of a proteasome related subunit N terminal domain | solution nmr | A | — | — |
| 2MQW | Solution structure of a proteasome related subunit N terminal domain | solution nmr | A | — | — |
| 2MR3 | A subunit of 26S proteasome lid complex | solution nmr | A | — | — |
| 2MR3 | A subunit of 26S proteasome lid complex | solution nmr | A | — | — |
| 2MRI | Solution structure of a proteasome related subunit C terminal domain | solution nmr | A | — | — |
| 2MRI | Solution structure of a proteasome related subunit C terminal domain | solution nmr | A | — | — |
| 3J47 | Formation of an intricate helical bundle dictates the assembly of the 26S proteasome lid | electron microscopy | O | — | — |
| 3J47 | Formation of an intricate helical bundle dictates the assembly of the 26S proteasome lid | electron microscopy | O | — | — |
| 3JCK | Structure of the yeast 26S proteasome lid sub-complex | electron microscopy | F | — | — |
| 3JCK | Structure of the yeast 26S proteasome lid sub-complex | electron microscopy | F | — | — |
| 3JCO | Structure of yeast 26S proteasome in M1 state derived from Titan dataset | electron microscopy | O | — | — |
| 3JCP | Structure of yeast 26S proteasome in M2 state derived from Titan dataset | electron microscopy | O | — | — |
| 4CR2 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | O | — | — |
| 4CR2 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | O | — | — |
| 4CR3 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | O | — | — |
| 4CR3 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | O | — | — |
| 4CR4 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | O | — | — |
| 4CR4 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | O | — | — |
| 5A5B | Structure of the 26S proteasome-Ubp6 complex | electron microscopy | O | — | — |
| 5A5B | Structure of the 26S proteasome-UBP6 complex | electron microscopy | O | — | — |
| 5MPB | 26S proteasome in presence of AMP-PNP (s3) | electron microscopy | O | — | — |
| 5MPC | 26S proteasome in presence of BeFx (s4) | electron microscopy | O | — | — |
| 5MPD | 26S proteasome in presence of ATP (s1) | electron microscopy | O | — | 1 (best 0.72) |
| 5MPD | 26S proteasome in presence of ATP (S1) | electron microscopy | O | — | — |
| 5MPE | 26S proteasome in presence of ATP (s2) | electron microscopy | O | — | — |
| 5MPE | 26S proteasome in presence of ATP (S2) | electron microscopy | O | — | — |
| 5WVI | The resting state of yeast proteasome | electron microscopy | O | — | — |
| 6FVT | 26S proteasome, s1 state | electron microscopy | O | — | — |
| 6FVU | 26S proteasome, s2 state | electron microscopy | O | — | 1 (best 0.78) |
| 6FVV | 26S proteasome, s3 state | electron microscopy | O | — | — |
| 6FVW | 26S proteasome, s4 state | electron microscopy | O | — | — |
| 6J2C | Yeast proteasome in translocation competent state (C3-a) | electron microscopy | O | — | 1 (best 0.78) |
| 6J2N | yeast proteasome in substrate-processing state (C3-b) | electron microscopy | O | — | 2 (best 0.86) |
| 6J2X | Yeast proteasome in resting state (C1-a) | electron microscopy | O | — | — |
| 7QO3 | Structure of the 26S proteasome-Ubp6 complex in the si state (Core Particle and Lid) | electron microscopy | O | — | 1 (best 0.71) |
| 7QO3 | Structure of the 26S proteasome-UBP6 complex in the si state (core particle and lid) | electron microscopy | O | — | — |
| 7QO5 | 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state | electron microscopy | O | — | 1 (best 0.79) |
| 7QO6 | 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the s2 state | electron microscopy | O | — | — |
| Q04062 | AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN9 (Q04062) | predicted | A | — | 6 (best 0.67) |
Experiment against prediction
- 3JCK chain F against the predicted model Q04062: TM-score 0.92, RMSD 2.31 Å
- 3JCK chain F against the predicted model Q04062: TM-score 0.92, RMSD 2.31 Å
- 2MRI chain A against the predicted model Q04062: TM-score 0.90, RMSD 1.84 Å
- 2MRI chain A against the predicted model Q04062: TM-score 0.90, RMSD 1.84 Å
- 7QO6 chain O against the predicted model Q04062: TM-score 0.89, RMSD 2.73 Å
- 6FVU chain O against the predicted model Q04062: TM-score 0.89, RMSD 2.74 Å
- 6FVV chain O against the predicted model Q04062: TM-score 0.89, RMSD 2.68 Å
- 6FVT chain O against the predicted model Q04062: TM-score 0.89, RMSD 2.80 Å
- 5MPD chain O against the predicted model Q04062: TM-score 0.88, RMSD 2.72 Å
- 5MPD chain O against the predicted model Q04062: TM-score 0.88, RMSD 2.72 Å
Elsewhere
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