MolNFT v1 · #311590 · protein
AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit 6B homolog (P33298)
P33298: “AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit 6B homolog (P33298)”. 3 pockets (best druggability 0.48). MolNFT v1 #311590 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P33298
- Type
- protein
- Length
- 428 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf9efD8B618ef85CA2BCA3999e3Fb10b1502864Cd
- Molecule
- 26S proteasome regulatory subunit 6B homolog
- UniProt
- P33298
- Pockets
- 3 · best druggability 0.48
Structure
1 distinct chain · 45% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 26S proteasome regulatory subunit 6B homolog | protein | 428 | 45% helix, 16% strand | P33298 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 101 | 0.48 | 0.80 | 18 | empty |
| 2 | 69 | 0.33 | 0.75 | 18 | empty |
| 3 | 50 | 0.32 | 0.78 | 16 | empty |
Compared structures
- 7QO5 · 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state · an experimental structure of the same protein · chain A against K, TM-score 0.87
- 6FVU · 26S proteasome, s2 state · an experimental structure of the same protein · chain A against K, TM-score 0.86
- 6FVT · 26S proteasome, s1 state · an experimental structure of the same protein · chain A against K, TM-score 0.86
- 5MPA · 26S proteasome in presence of ATP (S2) · an experimental structure of the same protein · chain A against K, TM-score 0.85
- 5MPA · 26S proteasome in presence of ATP (s2) · an experimental structure of the same protein · chain A against K, TM-score 0.85
- 6FVX · 26S proteasome, s5 state · an experimental structure of the same protein · chain A against K, TM-score 0.85
- 5MP9 · 26S proteasome in presence of ATP (s1) · an experimental structure of the same protein · chain A against K, TM-score 0.85
- 5MP9 · 26S proteasome in presence of ATP (S1) · an experimental structure of the same protein · chain A against K, TM-score 0.85
- 6J2X · Yeast proteasome in resting state (C1-a) · an experimental structure of the same protein · chain A against K, TM-score 0.83
- 6J2Q · Yeast proteasome in Ub-accepted state (C1-b) · an experimental structure of the same protein · chain A against K, TM-score 0.83
- 6J30 · yeast proteasome in Ub-engaged state (C2) · an experimental structure of the same protein · chain A against K, TM-score 0.82
- 5WVI · The resting state of yeast proteasome · an experimental structure of the same protein · chain A against K, TM-score 0.81
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P33298
- Elsewhere: UniProt P33298 · AlphaFold DB P33298
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