UniProt P33297
26S proteasome regulatory subunit 6A (P33297)
26S proteasome regulatory subunit 6A (UniProt P33297): 35 experimental structures on GenesisL1, 4 ligands bound, 46 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P33297
- Protein
- 26S proteasome regulatory subunit 6A
- Experimental structures
- 35
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 46 · 9 records with a druggable one
Structures
35 records of P33297 in the MolNFT archive: 35 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JCO | Structure of yeast 26S proteasome in M1 state derived from Titan dataset | electron microscopy | M | — | — |
| 3JCP | Structure of yeast 26S proteasome in M2 state derived from Titan dataset | electron microscopy | M | — | — |
| 3WHK | Crystal structure of PAN-Rpt5C chimera | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3WHK | Crystal structure of pan-RPT5C chimera | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3WHL | Crystal structure of Nas2 N-terminal domain complexed with PAN-Rpt5C chimera | x-ray diffraction | A, C, E, G | — | — |
| 3WHL | Crystal structure of NAS2 N-terminal domain complexed with pan-RPT5C chimera | x-ray diffraction | A, C, E, G | — | — |
| 4CR2 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | M | — | — |
| 4CR2 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | M | — | — |
| 4CR3 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | M | — | — |
| 4CR3 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | M | — | — |
| 4CR4 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | M | — | — |
| 4CR4 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | M | — | — |
| 5A5B | Structure of the 26S proteasome-Ubp6 complex | electron microscopy | M | — | — |
| 5A5B | Structure of the 26S proteasome-UBP6 complex | electron microscopy | M | — | — |
| 5MP9 | 26S proteasome in presence of ATP (s1) | electron microscopy | M | ATP, MG | — |
| 5MP9 | 26S proteasome in presence of ATP (S1) | electron microscopy | M | ATP, MG | — |
| 5MPA | 26S proteasome in presence of ATP (S2) | electron microscopy | M | ATP, MG | — |
| 5MPB | 26S proteasome in presence of AMP-PNP (s3) | electron microscopy | M | ANP, ADP, MG | 3 (best 0.84) |
| 5MPC | 26S proteasome in presence of BeFx (s4) | electron microscopy | M | ATP, MG | — |
| 5WVI | The resting state of yeast proteasome | electron microscopy | M | — | — |
| 6EF0 | Yeast 26S proteasome bound to ubiquitinated substrate (1D* motor state) | electron microscopy | M | ADP | 7 (best 0.82) |
| 6EF0 | Yeast 26S proteasome bound to ubiquitinated substrate (1D* motor state) | electron microscopy | M | ADP | — |
| 6EF1 | Yeast 26S proteasome bound to ubiquitinated substrate (5D motor state) | electron microscopy | M | ADP | 5 (best 0.85) |
| 6EF1 | Yeast 26S proteasome bound to ubiquitinated substrate (5D motor state) | electron microscopy | M | ADP | — |
| 6EF2 | Yeast 26S proteasome bound to ubiquitinated substrate (5T motor state) | electron microscopy | M | ATP | 6 (best 0.83) |
| 6EF2 | Yeast 26S proteasome bound to ubiquitinated substrate (5T motor state) | electron microscopy | M | ATP | — |
| 6EF3 | Yeast 26S proteasome bound to ubiquitinated substrate (4D motor state) | electron microscopy | M | ATP | 6 (best 0.82) |
| 6EF3 | Yeast 26S proteasome bound to ubiquitinated substrate (4D motor state) | electron microscopy | M | ATP | — |
| 6FVT | 26S proteasome, s1 state | electron microscopy | M | MG, ATP | — |
| 6FVU | 26S proteasome, s2 state | electron microscopy | M | ATP, MG | 6 (best 0.86) |
| 6FVV | 26S proteasome, s3 state | electron microscopy | M | ATP, MG, ADP | 3 (best 0.80) |
| 6FVW | 26S proteasome, s4 state | electron microscopy | M | ATP, MG | 6 (best 0.81) |
| 6J2C | Yeast proteasome in translocation competent state (C3-a) | electron microscopy | M | — | 4 (best 0.83) |
| 6J2X | Yeast proteasome in resting state (C1-a) | electron microscopy | M | — | — |
| P33297 | AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit 6A (P33297) | — | — | — |
Ligands
Elsewhere
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