UniProt Q08723
26S proteasome regulatory subunit RPN8 (Q08723)
26S proteasome regulatory subunit RPN8 (UniProt Q08723): 48 experimental structures on GenesisL1, 27 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q08723
- Protein
- 26S proteasome regulatory subunit RPN8
- Experimental structures
- 48
- Predicted models
- 0
- Pockets
- 27 · 10 records with a druggable one
Structures
48 records of Q08723 in the MolNFT archive: 48 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3J47 | Formation of an intricate helical bundle dictates the assembly of the 26S proteasome lid | electron microscopy | U | — | — |
| 3J47 | Formation of an intricate helical bundle dictates the assembly of the 26S proteasome lid | electron microscopy | U | — | — |
| 3JCK | Structure of the yeast 26S proteasome lid sub-complex | electron microscopy | E | — | — |
| 3JCK | Structure of the yeast 26S proteasome lid sub-complex | electron microscopy | E | — | — |
| 3JCO | Structure of yeast 26S proteasome in M1 state derived from Titan dataset | electron microscopy | U | — | — |
| 3JCP | Structure of yeast 26S proteasome in M2 state derived from Titan dataset | electron microscopy | U | — | — |
| 4CR2 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | U | — | — |
| 4CR2 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | U | — | — |
| 4CR3 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | U | — | — |
| 4CR3 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | U | — | — |
| 4CR4 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | U | — | — |
| 4CR4 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | U | — | — |
| 4O8X | Zinc-bound Rpn11 in complex with Rpn8 | x-ray diffraction | A | — | — |
| 4O8X | Zinc-bound RPN11 in complex with RPN8 | x-ray diffraction | A | — | — |
| 4O8Y | Zinc-free Rpn11 in complex with Rpn8 | x-ray diffraction | A | — | — |
| 4O8Y | Zinc-free RPN11 in complex with RPN8 | x-ray diffraction | A | — | — |
| 4OCL | Crystal Structure of the Rpn8-Rpn11 MPN domain heterodimer, crystal form Ia | x-ray diffraction | A, D | — | — |
| 4OCL | Crystal structure of the RPN8-RPN11 mpn domain heterodimer, crystal form ia | x-ray diffraction | A, D | — | — |
| 4OCM | Crystal Structure of the Rpn8-Rpn11 MPN domain heterodimer, crystal form Ib | x-ray diffraction | A, D | — | — |
| 4OCM | Crystal structure of the RPN8-RPN11 mpn domain heterodimer, crystal form ib | x-ray diffraction | A, D | — | — |
| 4OCN | Crystal Structure of the Rpn8-Rpn11 MPN domain heterodimer, crystal form II | x-ray diffraction | A, D | — | — |
| 4OCN | Crystal structure of the RPN8-RPN11 mpn domain heterodimer, crystal form II | x-ray diffraction | A, D | — | — |
| 4OWP | Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of… | x-ray diffraction | A | — | — |
| 4OWP | Crystal structure of RPN11 in a heterodimer complex with RPN8, representing the active portion of… | x-ray diffraction | A | — | — |
| 5A5B | Structure of the 26S proteasome-Ubp6 complex | electron microscopy | U | — | — |
| 5A5B | Structure of the 26S proteasome-UBP6 complex | electron microscopy | U | — | — |
| 5MPB | 26S proteasome in presence of AMP-PNP (s3) | electron microscopy | U | — | 2 (best 0.83) |
| 5MPC | 26S proteasome in presence of BeFx (s4) | electron microscopy | U | — | — |
| 5MPD | 26S proteasome in presence of ATP (s1) | electron microscopy | U | — | 5 (best 0.81) |
| 5MPD | 26S proteasome in presence of ATP (S1) | electron microscopy | U | — | — |
| 5MPE | 26S proteasome in presence of ATP (s2) | electron microscopy | U | — | — |
| 5MPE | 26S proteasome in presence of ATP (S2) | electron microscopy | U | — | — |
| 5U4P | Protein-protein complex between 26S proteasome regulatory subunit RPN8, RPN11, and Ubiquitin S31 | x-ray diffraction | A | — | — |
| 5U4P | Protein-protein complex between 26S proteasome regulatory subunit RPN8, RPN11, and ubiquitin S31 | x-ray diffraction | A | — | — |
| 5W83 | Rpn8/Rpn11 dimer complex | x-ray diffraction | A | — | 5 (best 0.81) |
| 5W83 | RPN8/RPN11 dimer complex | x-ray diffraction | A | — | — |
| 5WVI | The resting state of yeast proteasome | electron microscopy | U | — | — |
| 6FVT | 26S proteasome, s1 state | electron microscopy | U | — | — |
| 6FVU | 26S proteasome, s2 state | electron microscopy | U | — | 2 (best 0.81) |
| 6FVV | 26S proteasome, s3 state | electron microscopy | U | — | 3 (best 0.79) |
| 6FVW | 26S proteasome, s4 state | electron microscopy | U | — | 2 (best 0.78) |
| 6J2C | Yeast proteasome in translocation competent state (C3-a) | electron microscopy | U | — | 1 (best 0.83) |
| 6J2X | Yeast proteasome in resting state (C1-a) | electron microscopy | U | — | — |
| 7QO3 | Structure of the 26S proteasome-Ubp6 complex in the si state (Core Particle and Lid) | electron microscopy | U | — | 3 (best 0.78) |
| 7QO3 | Structure of the 26S proteasome-UBP6 complex in the si state (core particle and lid) | electron microscopy | U | — | — |
| 7QO5 | 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state | electron microscopy | U | — | 3 (best 0.81) |
| 7QO6 | 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the s2 state | electron microscopy | U | — | 1 (best 0.84) |
| Q08723 | AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN8 (Q08723) | — | — | — |
Elsewhere
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