GL1X · GenesisL1 explorer

MolNFT v1 · #385771 · protein

AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN10 (P38886)

P38886: “AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN10 (P38886)”. 2 pockets (best druggability 0.49). MolNFT v1 #385771 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P38886
Type
protein
Length
268 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xb6928af8E36537c086d9ECbC974228d895800fDA
Molecule
26S proteasome regulatory subunit RPN10
UniProt
P38886
Pockets
2 · best druggability 0.49

Structure

1 distinct chain · 40% helix, 16% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A26S proteasome regulatory subunit RPN10protein26840% helix, 16% strandP38886

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1630.490.8519empty
2500.350.8016empty

Compared structures

  • 5MPE · 26S proteasome in presence of ATP (s2) · an experimental structure of the same protein · chain A against W, TM-score 0.70
  • 5MPE · 26S proteasome in presence of ATP (S2) · an experimental structure of the same protein · chain A against W, TM-score 0.70
  • 6FVX · 26S proteasome, s5 state · an experimental structure of the same protein · chain A against W, TM-score 0.70
  • 6FVU · 26S proteasome, s2 state · an experimental structure of the same protein · chain A against W, TM-score 0.69
  • 7QO5 · 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state · an experimental structure of the same protein · chain A against W, TM-score 0.69
  • 6FVV · 26S proteasome, s3 state · an experimental structure of the same protein · chain A against W, TM-score 0.69
  • 6FVY · 26S proteasome, s6 state · an experimental structure of the same protein · chain A against W, TM-score 0.69
  • 6FVT · 26S proteasome, s1 state · an experimental structure of the same protein · chain A against W, TM-score 0.69
  • 7QO3 · Structure of the 26S proteasome-UBP6 complex in the si state (core particle and lid) · an experimental structure of the same protein · chain A against W, TM-score 0.69
  • 7QO3 · Structure of the 26S proteasome-Ubp6 complex in the si state (Core Particle and Lid) · an experimental structure of the same protein · chain A against W, TM-score 0.69
  • 5MPC · 26S proteasome in presence of BeFx (s4) · an experimental structure of the same protein · chain A against W, TM-score 0.69
  • 5LN1 · Structure of ubiquitylated-RPN10 from yeast; · an experimental structure of the same protein · chain A against A, TM-score 0.69

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