MolNFT v1 · #385823 · protein
AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN7 (Q06103)
Q06103: “AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN7 (Q06103)”. 4 pockets (best druggability 0.64). MolNFT v1 #385823 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q06103
- Type
- protein
- Length
- 429 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x682b1Ade9797D7737EF045Ba7770A53e5CF3c3Bc
- Molecule
- 26S proteasome regulatory subunit RPN7
- UniProt
- Q06103
- Pockets
- 4 · best druggability 0.64
Structure
1 distinct chain · 70% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 26S proteasome regulatory subunit RPN7 | protein | 429 | 70% helix, 3% strand | Q06103 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 296 | 0.64 | 0.80 | 35 | empty |
| 2 | 252 | 0.61 | 0.80 | 27 | empty |
| 3 | 135 | 0.47 | 0.78 | 23 | empty |
| 4 | 131 | 0.46 | 0.77 | 24 | empty |
Compared structures
- 6FVU · 26S proteasome, s2 state · an experimental structure of the same protein · chain A against R, TM-score 0.89
- 6FVV · 26S proteasome, s3 state · an experimental structure of the same protein · chain A against R, TM-score 0.88
- 6FVT · 26S proteasome, s1 state · an experimental structure of the same protein · chain A against R, TM-score 0.88
- 7QO3 · Structure of the 26S proteasome-Ubp6 complex in the si state (Core Particle and Lid) · an experimental structure of the same protein · chain A against R, TM-score 0.88
- 7QO3 · Structure of the 26S proteasome-UBP6 complex in the si state (core particle and lid) · an experimental structure of the same protein · chain A against R, TM-score 0.88
- 6FVW · 26S proteasome, s4 state · an experimental structure of the same protein · chain A against R, TM-score 0.87
- 6J2X · Yeast proteasome in resting state (C1-a) · an experimental structure of the same protein · chain A against R, TM-score 0.85
- 3JCO · Structure of yeast 26S proteasome in M1 state derived from Titan dataset · an experimental structure of the same protein · chain A against R, TM-score 0.85
- 5MPE · 26S proteasome in presence of ATP (s2) · an experimental structure of the same protein · chain A against R, TM-score 0.85
- 5MPE · 26S proteasome in presence of ATP (S2) · an experimental structure of the same protein · chain A against R, TM-score 0.85
- 5MPB · 26S proteasome in presence of AMP-PNP (s3) · an experimental structure of the same protein · chain A against R, TM-score 0.85
- 5MPD · 26S proteasome in presence of ATP (S1) · an experimental structure of the same protein · chain A against R, TM-score 0.84
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q06103
- Elsewhere: UniProt Q06103 · AlphaFold DB Q06103
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.