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AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN7 (Q06103)

Analyse AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN7… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q06103
Type
protein
Length
429 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x682b1Ade9797D7737EF045Ba7770A53e5CF3c3Bc
Molecule
26S proteasome regulatory subunit RPN7
UniProt
Q06103
Pockets
4 · best druggability 0.64

Structure

1 distinct chain · 70% helix, 3% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A26S proteasome regulatory subunit RPN7protein42970% helix, 3% strandQ06103

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12960.640.8035empty
22520.610.8027empty
31350.470.7823empty
41310.460.7724empty

Compared structures

  • 6FVU · 26S proteasome, s2 state · an experimental structure of the same protein · chain A against R, TM-score 0.89
  • 7QO5 · 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state · an experimental structure of the same protein · chain A against R, TM-score 0.89
  • 6FVX · 26S proteasome, s5 state · an experimental structure of the same protein · chain A against R, TM-score 0.89
  • 6FVV · 26S proteasome, s3 state · an experimental structure of the same protein · chain A against R, TM-score 0.88
  • 6FVT · 26S proteasome, s1 state · an experimental structure of the same protein · chain A against R, TM-score 0.88
  • 7QO3 · Structure of the 26S proteasome-Ubp6 complex in the si state (Core Particle and Lid) · an experimental structure of the same protein · chain A against R, TM-score 0.88
  • 7QO3 · Structure of the 26S proteasome-UBP6 complex in the si state (core particle and lid) · an experimental structure of the same protein · chain A against R, TM-score 0.88
  • 6FVY · 26S proteasome, s6 state · an experimental structure of the same protein · chain A against R, TM-score 0.88
  • 6FVW · 26S proteasome, s4 state · an experimental structure of the same protein · chain A against R, TM-score 0.87
  • 6J2Q · Yeast proteasome in Ub-accepted state (C1-b) · an experimental structure of the same protein · chain A against R, TM-score 0.85
  • 6J2X · Yeast proteasome in resting state (C1-a) · an experimental structure of the same protein · chain A against R, TM-score 0.85
  • 3JCO · Structure of yeast 26S proteasome in M1 state derived from Titan dataset · an experimental structure of the same protein · chain A against R, TM-score 0.85

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