UniProt P32565
26S proteasome regulatory subunit RPN2 (P32565)
26S proteasome regulatory subunit RPN2 (UniProt P32565): 29 experimental structures and 1 predicted model on GenesisL1, 38 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P32565
- Protein
- 26S proteasome regulatory subunit RPN2
- Experimental structures
- 29
- Predicted models
- 1
- Pockets
- 38 · 10 records with a druggable one
Structures
30 records of P32565 in the MolNFT archive: 29 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JCO | Structure of yeast 26S proteasome in M1 state derived from Titan dataset | electron microscopy | N | — | — |
| 3JCP | Structure of yeast 26S proteasome in M2 state derived from Titan dataset | electron microscopy | N | — | — |
| 4ADY | Crystal structure of 26S proteasome subunit Rpn2 | x-ray diffraction | A, B | — | — |
| 4ADY | Crystal structure of 26S proteasome subunit RPN2 | x-ray diffraction | A, B | — | — |
| 4CR2 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | N | — | — |
| 4CR2 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | N | — | — |
| 4CR3 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | N | — | — |
| 4CR3 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | N | — | — |
| 4CR4 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | N | — | — |
| 4CR4 | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S… | electron microscopy | N | — | — |
| 5A5B | Structure of the 26S proteasome-Ubp6 complex | electron microscopy | N | — | — |
| 5A5B | Structure of the 26S proteasome-UBP6 complex | electron microscopy | N | — | — |
| 5MPB | 26S proteasome in presence of AMP-PNP (s3) | electron microscopy | N | — | 3 (best 0.83) |
| 5MPC | 26S proteasome in presence of BeFx (s4) | electron microscopy | N | — | — |
| 5MPD | 26S proteasome in presence of ATP (s1) | electron microscopy | N | — | 5 (best 0.81) |
| 5MPD | 26S proteasome in presence of ATP (S1) | electron microscopy | N | — | — |
| 5MPE | 26S proteasome in presence of ATP (s2) | electron microscopy | N | — | — |
| 5MPE | 26S proteasome in presence of ATP (S2) | electron microscopy | N | — | — |
| 5WVI | The resting state of yeast proteasome | electron microscopy | N | — | — |
| 6FVT | 26S proteasome, s1 state | electron microscopy | N | — | — |
| 6FVU | 26S proteasome, s2 state | electron microscopy | N | — | 2 (best 0.83) |
| 6FVV | 26S proteasome, s3 state | electron microscopy | N | — | 3 (best 0.84) |
| 6FVW | 26S proteasome, s4 state | electron microscopy | N | — | 2 (best 0.84) |
| 6J2C | Yeast proteasome in translocation competent state (C3-a) | electron microscopy | N | — | 2 (best 0.85) |
| 6J2X | Yeast proteasome in resting state (C1-a) | electron microscopy | N | — | — |
| 7QO3 | Structure of the 26S proteasome-Ubp6 complex in the si state (Core Particle and Lid) | electron microscopy | N | — | 4 (best 0.86) |
| 7QO3 | Structure of the 26S proteasome-UBP6 complex in the si state (core particle and lid) | electron microscopy | N | — | — |
| 7QO5 | 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state | electron microscopy | N | — | 3 (best 0.83) |
| 7QO6 | 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the s2 state | electron microscopy | N | — | 1 (best 0.86) |
| P32565 | AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN2 (P32565) | predicted | A | — | 13 (best 0.85) |
Experiment against prediction
- 4ADY chain B against the predicted model P32565: TM-score 0.99, RMSD 1.00 Å
- 4ADY chain B against the predicted model P32565: TM-score 0.99, RMSD 1.00 Å
- 4ADY chain A against the predicted model P32565: TM-score 0.96, RMSD 2.08 Å
- 4ADY chain A against the predicted model P32565: TM-score 0.96, RMSD 2.08 Å
- 4CR2 chain N against the predicted model P32565: TM-score 0.93, RMSD 2.84 Å
- 4CR2 chain N against the predicted model P32565: TM-score 0.93, RMSD 2.84 Å
- 4CR3 chain N against the predicted model P32565: TM-score 0.93, RMSD 2.84 Å
- 4CR3 chain N against the predicted model P32565: TM-score 0.93, RMSD 2.84 Å
- 5A5B chain N against the predicted model P32565: TM-score 0.93, RMSD 2.84 Å
- 5A5B chain N against the predicted model P32565: TM-score 0.93, RMSD 2.84 Å
Elsewhere
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