MolNFT v2 · #175721 · protein
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1
7B5L: “Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly…”. Electron microscopy at 3.8, 2 ligands (SY8, ZN). MolNFT v2 #175721 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7B5L
- Type
- protein
- Length
- 2,654 residues
- Chains
- 12
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.8
- Source
- Homo sapiens
- UniProt
- Q13616, Q9Y4X5, Q13309, P61024, P63208, P0CG48, Q15843, P62877, P68036, P24941, P20248, P46527
- Ligands
- SY8, ZN
Structure
electron microscopy · resolution 3.8 · 12 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C | — | protein | 706 | — | Q13616 |
| H | — | protein | 423 | — | Q9Y4X5 |
| T | — | protein | 321 | — | Q13309 |
| K | — | protein | 69 | — | P61024 |
| S | — | protein | 138 | — | P63208 |
| U | — | protein | 75 | — | P0CG48 |
| N | — | protein | 76 | — | Q15843 |
| R | — | protein | 81 | — | P62877 |
| D | — | protein | 151 | — | P68036 |
| L | — | protein | 284 | — | P24941 |
| Y | — | protein | 253 | — | P20248 |
| P | — | protein | 77 | — | P46527 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7B5L · Ubiquitin ligation to F-box protein substrates by scf-rbr E3-E3 super- assembly… · the same entry in another collection · chain Y against Y, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13616
- Every structure of UniProt Q9Y4X5
- Every structure of UniProt Q13309
- Every structure of UniProt P61024
- Every structure of UniProt P63208
- Every structure of UniProt P0CG48
- Every structure of UniProt Q15843
- Every structure of UniProt P62877
- Every structure of UniProt P68036
- Every structure of UniProt P24941
- Every structure of UniProt P20248
- Every structure of UniProt P46527
- Elsewhere: RCSB PDB 7B5L · PDBe 7B5L · UniProt Q13616 · UniProt Q9Y4X5 · UniProt Q13309 · UniProt P61024 · UniProt P63208 · UniProt P0CG48 · UniProt Q15843 · UniProt P62877 · UniProt P68036 · UniProt P24941 · UniProt P20248 · UniProt P46527
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